[Ala1,3,11,15]-Endothelin (53-63)
[Ala1,3,11,15]-Endothelin (53-63) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) has selectivity for ETB with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) can be used for the research of vasoconstriction
For research use only. We do not sell to patients.
- CAS No.: 121204-87-3
- Formula: C109H163N25O32S
- Molecular Weight:2367.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
![[Ala1,3,11,15]-Endothelin (53-63) Chemical Structure](https://file.medchemexpress.com/product_pic/hy-p1019.gif "Click to View [Ala1,3,11,15]-Endothelin (53-63) Chemical Structure")
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50 for ETB: 0.61 nM (Bronchus); 0.61 nM (Lung); 0.33 nM (Cerebellum); 2200 nM (VSMC)[1]
[Ala1,3,11,15]-Endothelin (53-63) (0.1 μM) has selectivity for ETB with IC50 values of 0.61 nM, 0.61 nM, 0.33 nM, 2200 nM in Bronchus, Lung, Cerebellum and VSMC, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 121204-87-3
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Molecular Weight 2367.67
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Formula C109H163N25O32S
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Sequence Shortening
ASASSLMDKEAVYFAHLDIIW
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
[Ala1,3,11,15]-Endothelin (53-63) Related Classifications
HY-P1019 Related Classifications
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