1. GPCR/G Protein
  2. Endothelin Receptor
  3. [Ala1,3,11,15]-Endothelin (53-63)

[Ala1,3,11,15]-Endothelin (53-63) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) has selectivity for ETB with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) can be used for the research of vasoconstriction

For research use only. We do not sell to patients.

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[Ala1,3,11,15]-Endothelin (53-63) Chemical Structure

[Ala1,3,11,15]-Endothelin (53-63) Chemical Structure

CAS No. : 121204-87-3

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Description

[Ala1,3,11,15]-Endothelin (53-63) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) has selectivity for ETB with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) can be used for the research of vasoconstriction[1]

IC50 & Target

IC50 for ETB: 0.61 nM (Bronchus); 0.61 nM (Lung); 0.33 nM (Cerebellum); 2200 nM (VSMC)[1]

In Vitro

[Ala1,3,11,15]-Endothelin (53-63) (0.1 μM) has selectivity for ETB with IC50 values of 0.61 nM, 0.61 nM, 0.33 nM, 2200 nM in Bronchus, Lung, Cerebellum and VSMC, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2367.67

Formula

C109H163N25O32S

CAS No.
Sequence Shortening

ASASSLMDKEAVYFAHLDIIW

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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[Ala1,3,11,15]-Endothelin (53-63) Related Classifications

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Help & FAQs
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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[Ala1,3,11,15]-Endothelin (53-63)
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