Sarafotoxin S6c
Based on 1 Customer Validation
Sarafotoxin S6c (SRTX-c) is a potent endothelin-B receptor agonist. Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels.
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- Reinheit: 98.19%
- CAS. Nr.: 121695-87-2
- Formel: C103H147N27O37S5
- Molecular Weight:2515.75
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Speicherung:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
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Biologische Aktivität
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Chemical Information
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Help & FAQs
![[Ala1,3,11,15]-Endothelin (53-63)](https://file.medchemexpress.com/product_pic/hy-p1019.gif)
Biologische Aktivität
Beschreibung
IC50 & Target
Endothelin-B receptor[1]
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Wister rats, exposed to 10% O2 [chronic hypoxic (CH) rats] or room air (control rats) for 2 weeks[1]
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Dosage:1 pM-1 mM
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Administration:
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Result:Chronic hypoxia had effect on the sensitivity of the main pulmonary arteries to SCS6c, and small vasoconstrictor responses to were evident.
Caused vasoconstriction with a maximum response 30% of that to ET-1 in both endothelium-intact and endothelium-denuded vessels.
Chemical Information
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CAS. Nr. 121695-87-2
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Appearance Solid
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Molecular Weight 2515.75
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Formel C103H147N27O37S5
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Color White to off-white
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Synonyms
SRTX-c
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Sequence Shortening
CTCNDMTDEECLNFCHQDVIW (Disulfide bridge: Cys1-Cys15; Cys3-Cys11)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Reinheit & Dokumentation
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Data Sheet (261 KB)
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SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Sarafotoxin S6c Related Classifications
HY-102029 Related Classifications
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