[Ala1,3,11,15]-Endothelin (53-63) TFA
Based on 1 Customer Validation
[Ala1,3,11,15]-Endothelin (53-63) (TFA) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) (TFA) has selectivity for ETB with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) (TFA) can be used for the research of vasoconstriction.
For research use only. We do not sell to patients.
- Purity: 98.18%
- Formula: C111H164F3N25O34S
- Molecular Weight:2481.70
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
![[Ala1,3,11,15]-Endothelin (53-63) TFA Chemical Structure](https://file.medchemexpress.com/product_pic/hy-p1019a.gif "Click to View [Ala1,3,11,15]-Endothelin (53-63) TFA Chemical Structure")
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ETB |
[Ala1,3,11,15]-Endothelin (53-63) (TFA) (0.1 μM) has selectivity for ETB with IC50 values of 0.61 nM, 0.61 nM, 0.33 nM, 2200 nM in Bronchus, Lung, Cerebellum and VSMC, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 2481.70
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Formula C111H164F3N25O34S
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Color White to off-white
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Sequence
Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp
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Sequence Shortening
ASASSLMDKEAVYFAHLDIIW
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (20.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.4029 mL | 2.0147 mL | 4.0295 mL | 10.0737 mL |
| 5 mM | 0.0806 mL | 0.4029 mL | 0.8059 mL | 2.0147 mL | |
| 10 mM | 0.0403 mL | 0.2015 mL | 0.4029 mL | 1.0074 mL | |
| 15 mM | 0.0269 mL | 0.1343 mL | 0.2686 mL | 0.6716 mL | |
| 20 mM | 0.0201 mL | 0.1007 mL | 0.2015 mL | 0.5037 mL |
[Ala1,3,11,15]-Endothelin (53-63) TFA Related Classifications
HY-P1019A Related Classifications
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