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Apraglutide (Synonyms: FE 203799)

Cat. No.: HY-P1714 Purity: 98.45%
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Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Apraglutide Chemical Structure

Apraglutide Chemical Structure

CAS No. : 1295353-98-8

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5 mg USD 450 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum[1].

In Vivo

Apraglutide (FE 203799; 5 mg/kg/dose, subcutaneously, twice on days 0 and 4 postsurgery) treated piglets are healthy, have significant lower fecal fat and energy losses and exhibite intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth on day 7[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: NewbornDuroc piglets, 2–5 days old and weighing between 2-2.6 kg[1].
Dosage: 5 mg/kg/dose.
Administration: Subcutaneously, twice on days 0 and 4 postsurgery.
Result: On day 7, treated piglets were healthy, had significant lower fecal fat and energy losses and exhibited intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth.
Clinical Trial
Molecular Weight

3765.25

Formula

C₁₇₂H₂₆₃N₄₃O₅₂

CAS No.
Sequence Shortening

HGDGSFSDEX FTILDLLAAR DFINWLIQTK ITD-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
-20°C 1 year
In solvent -80°C 6 months
-20°C 1 month
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Product Name:
Apraglutide
Cat. No.:
HY-P1714
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