Phospholipid-PEG20000-Biotin
Phospholipid-PEG20000-Biotin is a phospholipid PEG derivative that has a biotin and a phospholipid bridged by a linear PEG linker. Phospholipid-PEG20000-Biotin can interact with avidinylated antibodies. Phospholipid-PEG20000-Biotin can be used to modify liposome and cells surface, and pancreatic islets for cell transplantation.
For research use only. We do not sell to patients.
- Molecular Weight:20000 (Average)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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Molecular Weight 20000 (Average)
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SMILES
O=C(NCCOCCOCCC(NCCOP(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)CCCC1SC[C@]([C@]1([H])N2)([H])NC2=O.[MW 20000]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Human Islet Cell Culture
The method of preserving islets in vitro, with purified reduced immunogenicity. The steps are islet isolation, islet cell purification, in vitro determination of islet function and islet cell culture.
Purity & Documentation
References
[1]. Chen Y, et al. A rapid and efficient technique for liposomal and nonliposomal drug pharmacokinetics studies using magnetic nanoprobes and its application to leakage kinetics of liposomes. J Chromatogr A. 2018 Dec 14;1580:2-11. [Content Brief]
[2]. Hodenius M, et al. Biotinylated Stealth magnetoliposomes. Chem Phys Lipids. 2002 Dec;120(1-2):75-85. [Content Brief]
[3]. Teramura Y, et al. Influence of molecular weight of PEG chain on interaction between streptavidin and biotin-PEG-conjugated phospholipids studied with QCM-D. Acta Biomater. 2016 Jan;30:135-143. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)