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Results for "

Obtained Inhibitors

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Aminopeptidase (1) Antibiotic (7) Apoptosis (2) Autophagy (1) Bacterial (9) Biochemical Assay Reagents (3) c-Myc (1) Calcium Channel (1) Chloride Channel (1) Cholinesterase (ChE) (2) COX (2) DNA/RNA Synthesis (1) Elastase (1) Fungal (5) Glucosidase (1) GSK-3 (1) HSV (1) Influenza Virus (1) NF-κB (2) NO Synthase (1) Orthopoxvirus (1) p38 MAPK (1) Phosphodiesterase (PDE) (1) PKC (1) Potassium Channel (1) Sodium Channel (2) β-catenin (1)
By Research Areas:	Cancer (11) Infection (14) Inflammation/Immunology (11) Metabolic Disease (2) Neurological Disease (7)

By Targets:

Akt (1)

Aminopeptidase (1)

Antibiotic (7)

Apoptosis (2)

Autophagy (1)

Bacterial (9)

Biochemical Assay Reagents (3)

c-Myc (1)

Calcium Channel (1)

Chloride Channel (1)

Cholinesterase (ChE) (2)

COX (2)

DNA/RNA Synthesis (1)

Elastase (1)

Fungal (5)

Glucosidase (1)

GSK-3 (1)

HSV (1)

Influenza Virus (1)

NF-κB (2)

NO Synthase (1)

Orthopoxvirus (1)

p38 MAPK (1)

Phosphodiesterase (PDE) (1)

PKC (1)

Potassium Channel (1)

Sodium Channel (2)

β-catenin (1)

By Research Areas:

Cancer (11)

Infection (14)

Inflammation/Immunology (11)

Metabolic Disease (2)

Neurological Disease (7)

Inhibitors & Agonists

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-103382

Arcyriaflavin A	Fungal	Infection
Arcyriaflavin A is a fungal metabolite obtained from the fungi, Nocardiopsis. Arcyriaflavin A is an inhibitor of CDK4 (IC₅₀ = 140 nM) and CaMKII (IC₅₀ = 25 nM) .

HY-N2211

Picfeltarraenin IB
Picfeltarraenin IB, a triterpenoid obtained from Picriafel-terrae Lour (P.fel-terrae), is an acetylcholinesterase (AChE) inhibitor. Picfeltarraenin IB can be used for the treatment of herpes infections, cancer and inflammation .

HY-119901

Eupatarone

Caleprunin B
Bacterial Infection

Eupatarone (Caleprunin B) is a bacterial inhibitor. Eupatarone can be obtained from Calea platylepis .

Eupatarone Caleprunin B	Bacterial	Infection
Eupatarone (Caleprunin B) is a bacterial inhibitor. Eupatarone can be obtained from Calea platylepis .

HY-121051

Aleurodiscal	Fungal Antibiotic	Infection
Aleurodiscal is an fungal inhibitor that can be obtained from cultures of Aleurodiscus mirabilis. Aleurodiscal can be used in the study of fungal infections .

HY-124481

Oleocanthal

COX Inflammation/Immunology

Oleocanthal is a COX-1/2 enzyme inhibitor and a nonsteroidal anti-inflammatory agent. Oleocanthal is obtained from virgin olive oil .

Oleocanthal	COX	Inflammation/Immunology
Oleocanthal is a COX-1/2 enzyme inhibitor and a nonsteroidal anti-inflammatory agent. Oleocanthal is obtained from virgin olive oil .

HY-N5076

Picfeltarraenin IV	Cholinesterase (ChE)	Infection Inflammation/Immunology Cancer
Picfeltarraenin IV, a triterpenoid obtained from Picriafel-terrae Lour (P.fel-terrae), is an acetylcholinesterase (AChE) inhibitor. Picfeltarraenin IV can be used for the treatment of herpes infections, cancer and inflammation .

HY-N1474

Picfeltarraenin IA
Picfeltarraenin IA, a triterpenoid obtained from Picriafel-terrae Lour (P.fel-terrae), is an acetylcholinesterase (AChE) inhibitor. Picfeltarraenin IA can be used for the treatment of herpes infections, cancer and inflammation .

HY-130294

Pyracrenic acid	Elastase	Inflammation/Immunology
Pyracrenic acid is an elastase inhibitor (IC₅₀ = 2.42 µM), can be obtained from the bark of Pyracantha crenulata. Pyracrenic acid has DPPH free radical scavenging activity and anti-inflammatory activity .

HY-P5855

μ-Conotoxin SxIIIC	Sodium Channel	Neurological Disease
μ-Conotoxin SxIIIC is an irreversible Na_V channel inhibitor that can be obtained from the Conus striolatus. μ-Conotoxin SxIIIC can be used in the study of neurological diseases such as chronic pain .

HY-125738

Obscurolide A1	Phosphodiesterase (PDE)	Neurological Disease Inflammation/Immunology
Obscurolide A1 is a Phosphodiesterase (PDE) inhibitor (IC₅₀=8 mM) that can be obtained from Streptomyces viridochromogenes culture. Obscurolide A1 has the potential to study neurological and inflammatory diseases .

HY-W009823

Phenyl benzoate	Chloride Channel	Others
Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid. Phenyl benzoate is a chloride transport blocker, inhibits Cl ^--dependent Glu accumulation into vesicles. Phenyl benzoate can be used as preservative in cosmetic products .

HY-N8760

Batatasin IV	Aminopeptidase	Inflammation/Immunology
Batatasin IV is an LTA4H inhibitor with anti-inflammatory activity. Batatasin IV is also a natural product that can be obtained from Dioscorea batatus. Batatasin IV can be used in research in the area of inflammation .

HY-N8475

6-Deoxyisojacareubin	PKC	Cancer
6-Deoxyisojacareubin is a PKC inhibitor that inhibits the proliferation of QGY-7703 cells in a concentration-dependent manner. 6-Deoxyisojacareubin is also a natural product that can be obtained from Garcinia nervosa. 6-Deoxyisojacareubin can be used in cancer research .

HY-N11912

Soladulcoside A	Biochemical Assay Reagents	Cancer
Soladulcoside A is a steroidal glycoside and antineoplastic agent that can be obtained from the whole plant of Solanum nigrum. Soladulcoside A can inhibit A549 cells and has the potential to study cancers such as non-small cell lung cancer (NSCLC) .

HY-P5020

Crotalicidin	Bacterial	Infection Cancer
Crotalicidin is an antimicrobial peptide and anti-tumor peptide that can effectively inhibit the activity of Gram-negative bacteria and tumor cells. Crotalicidin can be obtained from rattlesnake venom. Crotalicidin can be used in the study of microbial infections and cancer .

HY-111402

Pyridomycin Erizomycin; NSC 246134	Bacterial Antibiotic	Infection
Pyridomycin (Erizomycin) is a selective and low cytotoxic inhibitor of Mycobacterium tuberculosis that effectively targets InhA. Pyrdomycin is also an antibiotic that can be obtained from metabolites of Dactylosporangium fulvum. Pyrdomycin can be used in the study of bacterial infections such as tuberculosis .

HY-N9981

5β-Hydroxybufotalin	Biochemical Assay Reagents	Cancer
5β-Hydroxybufotalin (compound 6) is an anticancer agent that can effectively inhibit the growth activity of cancer cells. 5β-Hydroxybufotalin is also a natural product obtained from the chinese traditional drug Ch'an Su .

HY-125603

Termitomycamide B	Others	Neurological Disease
Termitomycamide B (compound 2) is a neuroprotective agent that can be obtained from Termitomyces titanicus. Termitomycamide B effectively inhibits endoplasmic reticulum stress-dependent cell death. Termitomycamide B can be used in the study of neurodegenerative diseases .

HY-N0072

Brazilin	Apoptosis Autophagy	Inflammation/Immunology Cancer
Brazilin is a red dye precursor obtained from the heartwood of several species of tropical hardwoods. Brazilin inhibits the cells proliferation, promotes apoptosis, and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities .

HY-N7263

Galanthamine N-Oxide	Cholinesterase (ChE)	Neurological Disease
Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC₅₀ of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes .

HY-N0253

Hederacoside C Kalopanaxsaponin B	Bacterial p38 MAPK NF-κB Apoptosis	Infection Inflammation/Immunology
Hederacoside C (Kalopanaxsaponin B) is an ingredient that can be obtained mainly from ivy leaves. Hederacoside C mediates inflammation by inhibiting activation of MAPK/NF-κB and its downstream signaling pathway. Hederacoside C has anti-inflammatory and antibacterial activity .

HY-N1969

3,3'-Di-O-methylellagic acid 3,8-Di-O-methylellagic acid
3,3'-Di-O-methylellagic acid obtained from Euphorbia adenochlora selectively inhibits the formation of acid-fastness in mycobacteria without retardation of their growth. 3,3'-di-O-methylellagic acid as a hepatoprotective compound is apparently due to its antioxidative effect .

HY-126771

Chrysomycin A Chr-A	Antibiotic Bacterial Akt GSK-3 β-catenin c-Myc	Infection Cancer
Chrysomycin A (Chr-A), an antibiotic, can be obtained from Streptomyces. Chrysomycin A exhibits antitumor and anti-tuberculous and MRSA activities. As for glioblastoma, Chrysomycin A inhibits the proliferation, migration, and invasion of cancer cells through the Akt/GSK-3β/β-catenin signaling pathway .

HY-P5863

Mambalgin-2 Mamb-2	Sodium Channel	Neurological Disease
Mambalgin-2 (Mamb-2) is an acid-sensitive ion channels (ASICs) inhibitor and a venom peptide. Mambalgin-2 can be obtained from the venom of the African black mamba. Mambalgin-2 can be used in the study of pain and neurological diseases .

HY-P5853

Aam-KTX	Potassium Channel	Inflammation/Immunology
Aam-KTX is a K_v channel inhibitor with IC₅₀ values of 1.1 nM and >750 nM for K_v1.3 and K_v1.1, respectively. Aam-KTX is a toxic peptide obtained from the venom of the scorpion Mesobuthus eupeus. Aam-KTX has potential in autoimmune diseases research .

HY-130430

Neplanocin A (-)-Neplanocin A	Antibiotic Orthopoxvirus	Infection Cancer
Neplanocin A ((-)-Neplanocin A) is an antitumor antibiotic with significant antitumor activity against murine L1210 leukemia. Neplanocin A is also an irreversible inhibitor of AdoHcy hydrolase (K_i=8.39 nM). Neplanocin A also has antiviral activity and is effective against vaccinia virus. Neplanocin A is obtained from Ampulariella regularis .

HY-100126

Tubercidin 4 Publications Verification 7-Deazaadenosine	Bacterial DNA/RNA Synthesis Influenza Virus Antibiotic	Infection
Tubercidin (7-Deazaadenosine) is an antibiotic obtained from Streptomyces tubercidicus. Tubercidin inhibits the growth of Streptococcus faecalis (8043) with an IC₅₀ of 0.02 μM . Tubercidin inhibits polymerases by incorporating DNA or RNA, thereby inhibiting DNA replication, RNA and protein synthesis . Tubercidin is a weak inhibitor of adenosine phosphorylase, and interferes with the phosphorylation of adenosine and AMP . Tubercidin has antiviral activity .

HY-P2699

ω-Grammotoxin SIA GrTx; ω-GsTx SIA	Calcium Channel	Neurological Disease
ω-Grammotoxin SIA (GrTx) is P/Q and N-type voltage-gated Calcium channels inhibitor. ω-Grammotoxin SIA is also a protein toxin that can be obtained from spider venom. ω-Grammotoxin SIA has the potential to study neurological diseases as well as cardiovascular diseases .

HY-126535

Magnoloside B	Glucosidase	Metabolic Disease Cancer
Magnoloside B is an α-glucosidase inhibitor (IC₅₀=0.69 mM), which can be obtained from Magnolia officinalis stem bark. Magnoloside B shows moderate inhibitory activity against MGC-803 and HepG2 cells. Magnoloside B has the potential to study cancer and diabetes .

HY-122076

A-26771B	Antibiotic Bacterial Fungal	Infection
A-26771B is an antibiotic can be obtained from Penicillium turbatum. A-26771B exhibits moderate antimicrobial activity against Gram-positive bacteria, mycoplasma, and fungi. A-26771B also inhibits potassium-dependent ATPase in rat liver mitochondria .

HY-N8519

Urdamycin B	Bacterial Fungal Antibiotic	Infection Cancer
Urdamycin B is an antibiotic that effectively inhibits fungi and bacteria. Urdamycin B also exhibits anti-proliferative activity against mouse leukemia cells L1210. Urdamycin B can be obtained from the metabolic products of Streptomyces fradiae. Urdamycin B can be used for research on cancer as well as bacterial and fungal infections .

HY-N7018

20-Hydroxyganoderic Acid G	Others	Inflammation/Immunology
20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC₅₀ of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the agent discovery of nerve inflammation diseases associated with microglia activated by LPS .

HY-N10177

Peniterphenyl A	HSV	Infection
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits HSV-1/2 virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-N8263

Nepetoidin B	Bacterial Fungal NF-κB	Infection Inflammation/Immunology
Nepetoidin B, an anti-inflammatory agent, inhibits inflammation by modulating the NF-κB and Nrf2/HO-1 signaling pathways. Nepetoidin B also has antifungal and antibacterial activity. Nepetoidin B is a natural product that can be obtained from Salvia plebeia R. Br. Nepetoidin B can be used in anti-inflammatory and anti-infectious research .

HY-N7907

Myricetin-3-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside	Others	Metabolic Disease
Myricetin-3-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside is a natural product that can be obtained from sphaerophysa salsula. Myricetin-3-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside inhibits triglyceride (TG) accumulation in 3T3-L1 adipocytes .

HY-N0396

Harpagoside 1 Publications Verification	COX NO Synthase	Inflammation/Immunology
Harpagoside can be obtained by Harpagophytum procumbens, which has anti-inflammatory, anti-cancer, protective activity, and efficacy. Harpagoside has an inhibitory effect on COX-1 and COX-2 active, and suppresses NO production. Harpagoside inhibits HepG2 cell lipid polysaccharide, which is a protein that is expressed horizontally and selectively, and has anti-inflammatory and latent pain effects. Harpagoside has the ability to protect the body, and has a degenerative effect on the β-oxidation (Aβ).

HY-N12079

(2,4-Dichloro-3,5-dimethoxyphenyl) methyl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside	Biochemical Assay Reagents	Cancer
(2,4-Dichloro-3,5-dimethoxyphenyl) methyl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside is an anticancer agent that inhibits the proliferation of lung cancer A549 cells (IC₅₀=29 μΜ). (2,4-Dichloro-3,5-dimethoxyphenyl) methyl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside can be obtained from Lilium regale and can be used in cancer research .

HY-N9199

6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid	Others	Others
6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid (Compound 14) is an osteoclast inhibitor with anti-osteoclastogenic activity. 6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid can be obtained from Eriobotrya japonica leaves. 6β,19-Dihydroxyurs-12-en-3-oxo-28-oic acid can be used in osteoporosis research .

Cat. No.	Product Name	Target	Research Area

HY-P5855

μ-Conotoxin SxIIIC	Sodium Channel	Neurological Disease
μ-Conotoxin SxIIIC is an irreversible Na_V channel inhibitor that can be obtained from the Conus striolatus. μ-Conotoxin SxIIIC can be used in the study of neurological diseases such as chronic pain .

HY-P5020

Crotalicidin	Bacterial	Infection Cancer
Crotalicidin is an antimicrobial peptide and anti-tumor peptide that can effectively inhibit the activity of Gram-negative bacteria and tumor cells. Crotalicidin can be obtained from rattlesnake venom. Crotalicidin can be used in the study of microbial infections and cancer .

HY-P5863

Mambalgin-2 Mamb-2	Sodium Channel	Neurological Disease
Mambalgin-2 (Mamb-2) is an acid-sensitive ion channels (ASICs) inhibitor and a venom peptide. Mambalgin-2 can be obtained from the venom of the African black mamba. Mambalgin-2 can be used in the study of pain and neurological diseases .

HY-P5853

Aam-KTX	Potassium Channel	Inflammation/Immunology
Aam-KTX is a K_v channel inhibitor with IC₅₀ values of 1.1 nM and >750 nM for K_v1.3 and K_v1.1, respectively. Aam-KTX is a toxic peptide obtained from the venom of the scorpion Mesobuthus eupeus. Aam-KTX has potential in autoimmune diseases research .

HY-P2699

ω-Grammotoxin SIA GrTx; ω-GsTx SIA	Calcium Channel	Neurological Disease
ω-Grammotoxin SIA (GrTx) is P/Q and N-type voltage-gated Calcium channels inhibitor. ω-Grammotoxin SIA is also a protein toxin that can be obtained from spider venom. ω-Grammotoxin SIA has the potential to study neurological diseases as well as cardiovascular diseases .

HY-P4873

Amylin (20-29) (human)	Peptides	Neurological Disease
Amylin (20-29) (human) is the fragment of human islet amyloid polypeptide (hIAPP) or Amylin. Amylin is a 37-residue hormone. Amylin (20-29) (human) is responsible for the amyloidogenic propensities of the full length protein. Amylin (20-29) (human) can be transformed into its corresponding peptoid and retropeptoid sequences, to obtain beta-sheet breaker peptides as amyloid inhibitors .

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