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Cat. No.: HY-N8475

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6-Deoxyisojacareubin

6-Deoxyisojacareubin is a PKC inhibitor that inhibits the proliferation of QGY-7703 cells in a concentration-dependent manner. 6-Deoxyisojacareubin is also a natural product that can be obtained from Garcinia nervosa. 6-Deoxyisojacareubin can be used in cancer research.

For research use only. We do not sell to patients.

CAS No.: 26486-92-0
Formula: C₁₈H₁₄O₅
Molecular Weight:310.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

6-Deoxyisojacareubin Chemical Structure

CAS No.: 26486-92-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All PKC Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
SH-SY5Y	EC₅₀	5.1 μM Compound: 19	Neuroprotective activity against 6-hydroxydopamine-induced human SH-SY5Y cell death after 24 hrs by MTT assay Neuroprotective activity against 6-hydroxydopamine-induced human SH-SY5Y cell death after 24 hrs by MTT assay	[PMID: 25051453]

Chemical Information

CAS No. 26486-92-0
Molecular Weight 310.30
Formula C₁₈H₁₄O₅
SMILES

O=C1C2=C(OC3=C1C=CC=C3O)C(C=CC(C)(C)O4)=C4C=C2O
Structure Classification
- Flavonoids
- Other Flavonoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dai M, Yuan X, Zhu ZJ, Shan L, Liu RH, Sun QY, Zhang WD. Efficient total synthesis and biological activities of 6-deoxyisojacareubin. Arch Pharm (Weinheim). 2013 Apr;346(4):314-20. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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6-Deoxyisojacareubin

All PKC Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

6-Deoxyisojacareubin Related Classifications

HY-N8475 Related Classifications