country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-130294

Copy Link Print Information

Pyracrenic acid

Pyracrenic acid is an elastase inhibitor (IC₅₀ = 2.42 µM), can be obtained from the bark of Pyracantha crenulata. Pyracrenic acid has DPPH free radical scavenging activity and anti-inflammatory activity.

For research use only. We do not sell to patients.

CAS No.: 80832-44-6
Formula: C₃₉H₅₄O₆
Molecular Weight:618.84

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Pyracrenic acid Chemical Structure

CAS No.: 80832-44-6

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	4.37 μM Compound: 5	Cytotoxicity against human A549 cells by SRB assay Cytotoxicity against human A549 cells by SRB assay	[PMID: 20176479]
A549	IC₅₀	9.9 μM Compound: 19	Cytotoxicity against human A549 cells assessed as inhibition of cell growth by SRB assay Cytotoxicity against human A549 cells assessed as inhibition of cell growth by SRB assay	[PMID: 28358502]
HCT-15	IC₅₀	>10 μM Compound: 19	Cytotoxicity against human HCT15 cells assessed as inhibition of cell growth by SRB assay Cytotoxicity against human HCT15 cells assessed as inhibition of cell growth by SRB assay	[PMID: 28358502]
HCT-15	IC₅₀	5.83 μM Compound: 5	Cytotoxicity against human HCT15 cells by SRB assay Cytotoxicity against human HCT15 cells by SRB assay	[PMID: 20176479]
SK-MEL-2	IC₅₀	>10 μM Compound: 19	Cytotoxicity against human SK-MEL-2 cells assessed as inhibition of cell growth by SRB assay Cytotoxicity against human SK-MEL-2 cells assessed as inhibition of cell growth by SRB assay	[PMID: 28358502]
SK-MEL-2	IC₅₀	9.72 μM Compound: 5	Cytotoxicity against human SK-MEL-2 cells by SRB assay Cytotoxicity against human SK-MEL-2 cells by SRB assay	[PMID: 20176479]
SK-MEL-28	IC₅₀	81.7 μM Compound: 124	Cytotoxicity against human SK-MEL-28 cells assessed as growth inhibition Cytotoxicity against human SK-MEL-28 cells assessed as growth inhibition	[PMID: 25599949]
SK-OV-3	IC₅₀	>10 μM Compound: 19	Cytotoxicity against human SKOV3 cells assessed as inhibition of cell growth by SRB assay Cytotoxicity against human SKOV3 cells assessed as inhibition of cell growth by SRB assay	[PMID: 28358502]
SK-OV-3	IC₅₀	7.04 μM Compound: 5	Cytotoxicity against human SKOV3 cells by SRB assay Cytotoxicity against human SKOV3 cells by SRB assay	[PMID: 20176479]
Vero	CC₅₀	6.9 μM Compound: betulinic acid 3beta-caffeate	Cytotoxicity against African green monkey Vero cells after 6 to 7 days by MTS assay Cytotoxicity against African green monkey Vero cells after 6 to 7 days by MTS assay	[PMID: 22439591]

In Vitro

Pyracrenic acid exhibits very strong elastase inhibition activity with an IC₅₀ value of 1.5 µg/mL (2.42 µM)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 80832-44-6
Molecular Weight 618.84
Formula C₃₉H₅₄O₆
SMILES

CC1(C)[C@@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)CC[C@]3(C)[C@@]4([H])CC[C@]5([H])[C@@]6([H])[C@H](C(C)=C)CC[C@@](C(O)=O)6CC[C@](C)5[C@@](C)4CC[C@@]13[H]
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Otsuka H, et al. Studies on anti-inflammatory agents. V. A new anti-inflammatory constituent of Pyracantha crenulata roem. Chem Pharm Bull (Tokyo). 1981 Nov;29(11):3099-104. [Content Brief]

[2]. Kim J H, et al. Compounds with elastase inhibition and free radical scavenging activities from Callistemon lanceolatus. J Med Plants Res. 2009, 3(11): 914-920.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote