94 Results for "

methyltetrazine

" in MedChemExpress (MCE) Product Catalog:
Products (94)

94 Results for "methyltetrazine" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-135140
CAS No.: 1345955-28-3
Purity:  98.02%
Research Areas:  

Others

Methyltetrazine-amine, a tetrazine compound, is used for the site-specific dual functionalization of the resulting bioconjugates .
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1
1 Cited Publications
Cat. No.: HY-A0248A
CAS No.: 4135-11-9
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
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1
1 Cited Publications
Cat. No.: HY-135140A
CAS No.: 1596117-29-1
Purity:  99.74%
Research Areas:  

Others

Methyltetrazine-Amine hydrochloride is a tetrazine compound. Methyltetrazine-Amine hydrochloride can be used for the site-specific dual functionalization of the resulting bioconjugates. Methyltetrazine-Amine hydrochloride can be added during protein precipitation in experiments using trans-cyclooctene .
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1
1 Cited Publications
Cat. No.: HY-P1108
CAS No.: 681260-70-8
Target:  

CRFR

Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
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1
1 Cited Publications
Cat. No.: HY-P1108A
Target:  

CRFR

Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC50=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .
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Cat. No.: HY-134124
CAS No.: 92614-59-0
Purity:  95.8%
Research Areas:  

Metabolic Disease

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
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Cat. No.: HY-141269
CAS No.: 1802907-92-1
Purity:  ≥97.0%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-141263
CAS No.: 1380500-88-8
Purity:  98.61%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Methyltetrazine-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-130283
CAS No.: 1644644-96-1
Purity:  98.61%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Cat. No.: HY-P10272
CAS No.: 1628323-80-7
Synonyms: PTG-300
Target:  

Ferroportin

Research Areas:  

Others

Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .
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Cat. No.: HY-141264
CAS No.: 1802907-91-0
Purity:  99.29%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Methyltetrazine-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-140313
CAS No.: 1802238-48-7
Purity:  95.22%
Target:  

ADC Linkers

Research Areas:  

Cancer

Methyltetrazine-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Methyltetrazine-DBCO also contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Cat. No.: HY-136104
Purity:  97.97%
Target:  

ADC Linkers

Research Areas:  

Cancer

Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Cat. No.: HY-141278
CAS No.: 1802908-02-6
Purity:  98.61%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Cat. No.: HY-151776
CAS No.: 2183473-57-4
Purity:  97.36%
Synonyms: TZ-Cy3
Cy3 methyltetrazine (TZ-Cy3) is a click chemistry reagent with methyltetrazine building blocks that is highly reactive towards cyclooctene. Cy3 methyltetrazine is also a tetrazine-modified fluorescent probe that can be used to analyze protein phosphorylation in solution and living cells .
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Cat. No.: HY-140940
CAS No.: 1835759-81-3
Purity:  98.12%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Cat. No.: HY-141284
CAS No.: 2353409-82-0
Target:  

ADC Linkers

Research Areas:  

Cancer

Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Gly-Gly-Gly-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Cat. No.: HY-159794
CAS No.: 2861998-16-3
Target:  

ADC Linkers

Research Areas:  

Cancer

Azido-methyltetrazine di-arm linker is a multivalent ADC linker for the synthesis of antibody-drug conjugates (ADCs) .
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Cat. No.: HY-141261A
CAS No.: 2245150-18-7
Research Areas:  

Others

Methyltetrazine-PEG4-amine hydrochloride is a PEG derivative containing a free amine and a methyltetrazine group. Methyltetrazine-PEG4-amine hydrochloride is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .
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Cat. No.: HY-160776
CAS No.: 2861998-18-5
Target:  

ADC Linkers

Research Areas:  

Cancer

Diazido-methyltetrazine tri-arm is an ADC linker that can be used to synthesize antibody-drug conjugates (ADCs). Diazido-methyltetrazine tri-arm can be applied to the research of refractory breast cancer .
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