Methyltetrazine-PEG4-amine hydrochloride
Based on 1 Customer Validation
Methyltetrazine-PEG4-amine hydrochloride is a linker for antibody-drug conjugates and a click chemistry reagent that can be used for the synthesis of ADCs. Methyltetrazine-PEG4-amine hydrochloride can be used to synthesize click-active albumin-binding radioligands as well as VLA-4-targeted radiopharmaceutical precursors. Methyltetrazine-PEG4-amine hydrochloride is applicable to research related to prostate cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.50%
- CAS. Nr.: 2245150-18-7
- Formel: C17H26ClN5O4
- Molecular Weight:399.87
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Speicherung:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
In Vitro
Methyltetrazine-PEG4-amine hydrochloride is a bifunctional linker commonly used in bioorthogonal labeling and antibody-drug conjugates (ADCs). Methyltetrazine-PEG4-amine hydrochloride consists of four functional moieties: the methyltetrazine group with catalyst-free ultrafast click chemistry activity, PEG4 which enhances water solubility and flexibility while reducing steric hindrance, an amine group with amide coupling activity, and hydrochloride which improves the storage and transportation stability of the overall reagent[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2245150-18-7
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Appearance Solid
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Molecular Weight 399.87
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Formel C17H26ClN5O4
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Color Purplish red to red
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SMILES
NCCOCCOCCOCCOC1=CC=C(C=C1)C2=NN=C(C)N=N2.Cl
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (250.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5008 mL | 12.5041 mL | 25.0081 mL | 62.5203 mL |
| 5 mM | 0.5002 mL | 2.5008 mL | 5.0016 mL | 12.5041 mL | |
| 10 mM | 0.2501 mL | 1.2504 mL | 2.5008 mL | 6.2520 mL | |
| 15 mM | 0.1667 mL | 0.8336 mL | 1.6672 mL | 4.1680 mL | |
| 20 mM | 0.1250 mL | 0.6252 mL | 1.2504 mL | 3.1260 mL | |
| 25 mM | 0.1000 mL | 0.5002 mL | 1.0003 mL | 2.5008 mL | |
| 30 mM | 0.0834 mL | 0.4168 mL | 0.8336 mL | 2.0840 mL | |
| 40 mM | 0.0625 mL | 0.3126 mL | 0.6252 mL | 1.5630 mL | |
| 50 mM | 0.0500 mL | 0.2501 mL | 0.5002 mL | 1.2504 mL | |
| 60 mM | 0.0417 mL | 0.2084 mL | 0.4168 mL | 1.0420 mL | |
| 80 mM | 0.0313 mL | 0.1563 mL | 0.3126 mL | 0.7815 mL | |
| 100 mM | 0.0250 mL | 0.1250 mL | 0.2501 mL | 0.6252 mL |
Methyltetrazine-PEG4-amine hydrochloride Related Classifications
HY-141261A Related Classifications
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