2245150-18-7
Chemical Structure
Methyltetrazine-PEG4-amine hydrochloride
- CAS No.: 2245150-18-7
- Formula:C17H26ClN5O4
- Molecular Weight:399.87
IUPAC Name: 2-(2-(2-(2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethan-1-amine hydrochloride
InChIKey: CXFRTHCHQZRAFJ-UHFFFAOYSA-N
SMILES: NCCOCCOCCOCCOC1=CC=C(C=C1)C2=NN=C(C)N=N2.Cl
Biological Activity: Methyltetrazine-PEG4-amine hydrochloride is a linker for antibody-drug conjugates and a click chemistry reagent that can be used for the synthesis of ADCs. Methyltetrazine-PEG4-amine hydrochloride can be used to synthesize click-active albumin-binding radioligands as well as VLA-4-targeted radiopharmaceutical precursors. Methyltetrazine-PEG4-amine hydrochloride is applicable to research related to prostate cancer[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Methyltetrazine-PEG4-amine hydrochloride | 99.50% | Methyltetrazine-PEG4-amine hydrochloride is a linker for antibody-drug conjugates and a click chemistry reagent that can be used for the synthesis of ADCs. Methyltetrazine-PEG4-amine hydrochloride can be used to synthesize click-active albumin-binding radioligands as well as VLA-4-targeted radiopharmaceutical precursors. Methyltetrazine-PEG4-amine hydrochloride is applicable to research related to prostate cancer. | ||||||||||||||||||||
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References
- [1]. He X, et al. Affinity-Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics. Advanced healthcare materials. 2026 Aug;15(29):e71385.
- [2]. Li, Longbo, et al. Effect of Click Chemistry Linkages on the Biological Behavior of Albumin-Binding 177Lu-DOTAGA-pIBA-LLP2A Analogues Targeting Melanoma. Bioconjugate Chemistry 36.9 (2025): 2002-2012.
- [3]. Muraki M, et al. Site-specific chemical conjugation of human Fas ligand extracellular domain using trans-cyclooctene - methyltetrazine reactions. BMC biotechnology. 2017 Jul 03;17(1):56. [Content Brief]
