Amino-PEG4-bis-PEG3-methyltetrazine
Amino-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
For research use only. We do not sell to patients.
- Formula: C58H90N14O17
- Molecular Weight:1255.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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Cleavable Linker |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1255.42
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Formula C58H90N14O17
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SMILES
NCCOCCOCCOCCOCCC(NC(COCCC(NCCOCCOCCOCCNC(CC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O)=O)COCCC(NCCOCCOCCOCCNC(CC3=CC=C(C4=NN=C(C)N=N4)C=C3)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)