Methyltetrazine-PEG4-SS-PEG4-methyltetrazine
Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyltetrazine-PEG4-SS-PEG4-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
For research use only. We do not sell to patients.
- Formula: C48H70N12O12S2
- Molecular Weight:1071.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Disulfide Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1071.27
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Formula C48H70N12O12S2
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SMILES
O=C(CCOCCOCCOCCOCCNC(CCSSCCC(NCCOCCOCCOCCOCCC(NCC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O)=O)=O)NCC3=CC=C(C4=NN=C(C)N=N4)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Methyltetrazine-PEG4-SS-PEG4-methyltetrazine Related Classifications
HY-130943 Related Classifications
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