Diazido-methyltetrazine tri-arm
Diazido-methyltetrazine tri-arm is an ADC linker that can be used to synthesize antibody-drug conjugates (ADCs). Diazido-methyltetrazine tri-arm can be applied to the research of refractory breast cancer.
For research use only. We do not sell to patients.
- CAS No.: 2861998-18-5
- Formula: C29H43N15O4
- Molecular Weight:665.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
The antibody-linker conjugate forms via microbial transglutaminase-mediated transpeptidation between Diazido-methyltetrazine tri-arm and the N297A anti-HER2 monoclonal antibody[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2861998-18-5
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Molecular Weight 665.75
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Formula C29H43N15O4
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SMILES
CC(N=N1)=NN=C1C(C=C2)=CC=C2CC(N[C@@H](CCCCN)C(N[C@@H](CCCCNC(CCN=[N+]=[N-])=O)C(NCCCN=[N+]=[N-])=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)