Methyltetrazine-SS-NHS
Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyltetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
For research use only. We do not sell to patients.
- CAS No.: 2740453-91-0
- Formula: C20H22N6O5S2
- Molecular Weight:490.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Disulfide Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2740453-91-0
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Molecular Weight 490.56
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Formula C20H22N6O5S2
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SMILES
CC1=NN=C(C2=CC=C(CNC(CCSSCCC(ON3C(CCC3=O)=O)=O)=O)C=C2)N=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)