Methyltetrazine-PEG8-N3
Methyltetrazine-PEG8-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Methyltetrazine-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C29H46N8O9
- Peso molecular:650.72
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Ver todos los productos específicos de isoformas PROTAC Linkers
More
Actividad biológica
Descripciòn
IC50 & Target
|
PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Peso molecular 650.72
-
Fòrmula C29H46N8O9
-
SMILES
CC1=NN=C(C2=CC=C(CNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)C=C2)N=N1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Methyltetrazine-PEG8-N3 Related Classifications
HY-133469 Related Classifications
Powered by Bioz