Methyltetrazine-amido-PEG7-azide
Methyltetrazine-amido-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Methyltetrazine-amido-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- No. CAS: 2112731-46-9
- Fòrmula: C27H42N8O8
- Peso molecular:606.67
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Ver todos los productos específicos de isoformas PROTAC Linkers
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Actividad biológica
Descripciòn
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2112731-46-9
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Peso molecular 606.67
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Fòrmula C27H42N8O8
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SMILES
O=C(NCC1=CC=C(C2=NN=C(C)N=N2)C=C1)CCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Methyltetrazine-amido-PEG7-azide Related Classifications
HY-141277 Related Classifications
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