2112731-46-9
Chemical Structure
Methyltetrazine-amido-PEG7-azide
- CAS No.: 2112731-46-9
- Formula:C27H42N8O8
- Molecular Weight:606.67
IUPAC Name: 1-azido-N-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzyl)-3,6,9,12,15,18,21-heptaoxatetracosan-24-amide
InChIKey: PQDMYSBOSSHIPG-UHFFFAOYSA-N
SMILES: O=C(NCC1=CC=C(C2=NN=C(C)N=N2)C=C1)CCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
Biological Activity: Methyltetrazine-amido-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Methyltetrazine-amido-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Methyltetrazine-amido-PEG7-azide | Methyltetrazine-amido-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Methyltetrazine-amido-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords
