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nitrogen-containing

" in MedChemExpress (MCE) Product Catalog:

61

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2

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11

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4

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11

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6

Isotope-Labeled Compounds

2

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126854
    N-Acetyllactosamine

    N-Acetyl-D-lactosamine

    		 Endogenous Metabolite Galectin Cardiovascular Disease
    N-Acetyllactosamine (N-Acetyl-D-lactosamine), a nitrogen-containing disaccharide, is a galectin-3 inhibitor, which is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects .
    N-Acetyllactosamine
  • HY-W013040
    Pyrazine

    1,4-Diazine

    		 Drug Intermediate Cardiovascular Disease Infection Inflammation/Immunology Cancer
    Pyrazine (1,4-Diazine) is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities .
    Pyrazine
  • HY-B0012
    Pamidronic acid
    1 Publications Verification

    		 RANKL/RANK Toll-like Receptor (TLR) Wnt β-catenin Metabolic Disease Inflammation/Immunology Cancer
    Pamidronic acid, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronic acid significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of OPG in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronic acid can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma .
    Pamidronic acid
  • HY-40351
    4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

    		Drug Intermediate Others
    4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a nitrogen-containing heterocyclic organic synthesis intermediate that can be used for the synthesis of JAK and PKB/Akt inhibitors .
    4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
  • HY-W034566
    Hexacyclen

    Hexaaza-18-crown-6; 1,4,7,10,13,16-Hexaazacyclooctadecane

    		 Biochemical Assay Reagents Others
    Hexacyclen is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. It is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions. Inhibitors of certain diseases such as cancer. In biochemistry, Hexacyclen is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Due to its large size and complex structure, Hexacyclen is not widely used in daily products or applications .
    Hexacyclen
  • HY-B0012A
    Pamidronate disodium
    1 Publications Verification

    CGP 23339A

    		 RANKL/RANK Toll-like Receptor (TLR) Wnt β-catenin Metabolic Disease Inflammation/Immunology Cancer
    Pamidronate disodium (CGP 23339A), the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma .
    Pamidronate disodium
  • HY-B0730
    Pamidronate disodium pentahydrate
    1 Publications Verification

    		 RANKL/RANK Toll-like Receptor (TLR) Wnt β-catenin Metabolic Disease Inflammation/Immunology Cancer
    Pamidronate disodium pentahydrate, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium pentahydrate significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium pentahydrate can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma .
    Pamidronate disodium pentahydrate
  • HY-D0006
    Bathophenanthroline

    		Fluorescent Dye Others
    Bathophenanthroline is a nitrogen-containing organic ligand that can form stable complexes with transition metal ions such as Ru 2+. In proteomics, Bathophenanthroline is often used for in-gel protein staining. The negatively charged sulfonic acid groups of Bathophenanthroline interact electrostatically with the positively charged amino acid residues of proteins, thereby achieving specific binding to proteins and enhancing the fluorescent signal of detection. Bathophenanthroline can be used for protein separation and detection in SDS-PAGE gels in the field of proteomics, as well as other fluorescence studies[1]. Ex/Em=532 nm/610 nm[1].
    Bathophenanthroline
  • HY-Y0519
    Pyrimidine

    		Endogenous Metabolite Neurological Disease Cancer
    Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .
    Pyrimidine
  • HY-W002457
    3-Nitropyrazole

    		Biochemical Assay Reagents Drug Intermediate Others
    3-Nitropyrazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 3-Nitropyrazole is also a nitrogen-containing heterocyclic compound, which can be used in the synthesis of other active compounds .
    3-Nitropyrazole
  • HY-W002016
    Phthalazine

    		Reactive Oxygen Species (ROS) Cancer
    Phthalazine is a substrate for human aldehyde oxidase 1, which can lead to the production of ROS and subsequent enzyme inactivation. Phthalazine is a nitrogen-containing organic heterocyclic compound. Phthalazine exhibits antitumor activity in blood cancer, breast cancer, colon cancer, lung cancer and renal cancer .
    Phthalazine
  • HY-159051
    Dragendorff reagent

    		Biochemical Assay Reagents Others
    Dragendorff reagent is used for detecting alkaloids and other nitrogen-containing compounds. Dragendorff reagent is a solution of potassium bismuth iodide composing of Basic bismuth nitrate (Bi(NO3)3), Tartaric acid (HY-N2436), and Potassium iodide (KI). When contact with alkaloids, Dragendorff reagent produces an orange or orange red precipitate .
    Dragendorff reagent
  • HY-W010628
    Azetidine hydrochloride

    Trimethyleneimine hydrochloride

    		 Biochemical Assay Reagents Drug Intermediate Others
    Azetidine (Trimethyleneimine) hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Azetidine hydrochloride is also a nitrogen-containing heterocyclic compound, which can be used in the synthesis of other active compounds .
    Azetidine hydrochloride
  • HY-P4545
    Abz-Gly-p-nitro-Phe-Pro-OH

    		Angiotensin Receptor Others
    Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .
    Abz-Gly-p-nitro-Phe-Pro-OH
  • HY-30012
    5-Bromo-7-azaindole

    		Biochemical Assay Reagents Drug Intermediate Others
    5-Bromo-7-azaindole is an important intermediate. 5-Bromo-7-azaindole can be used for the synthesis of other nitrogen-containing heterocyclic compounds .
    5-Bromo-7-azaindole
  • HY-W002458
    4-Nitropyrazole

    		Drug Intermediate Others
    4-Nitropyrazole is a five-membered nitrogen-containing heterocyclic compound that can be used as a drug intermediate. 4-Nitropyrazole can be synthesized into antibiotics/antifungal/antiviral agents containing pyrazole rings. 4-Nitropyrazole is synthesized through C-H activation reactions to produce LRRK2 inhibitors, which are used in the research of Parkinson's disease .
    4-Nitropyrazole
  • HY-Y0141
    3-Amino-6-chloropyridazine

    		Drug Intermediate Others
    3-Amino-6-chloropyridazine is a nitrogen-containing heterocyclic organic compound belonging to the pyridazine derivatives. 3-Amino-6-chloropyridazine has the basicity of amino groups and the nucleophilic substitution activity of chlorine atoms. 3-Amino-6-chloropyridazine can serve as an important intermediate for synthesizing some active compounds .
    3-Amino-6-chloropyridazine
  • HY-P4561
    H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH

    		Cathepsin Others
    H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
    H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH
  • HY-P4725
    Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2

    		Fluorescent Dye Others
    Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay .
    Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2
  • HY-B0515A
    Ibandronic acid

    		Others Cancer
    Ibandronic acid is a highly effective nitrogen-containing bisphosphonate that can be used for osteoporosis.
    Ibandronic acid
  • HY-W024652
    4,5-Dimethylimidazole

    		Drug Intermediate Others
    4,5-Dimethylimidazole is a nitrogen-containing heterocyclic compound and is a synthetic intermediate .
    4,5-Dimethylimidazole
  • HY-W015947
    1,2-Dimethylimidazole

    		Drug Intermediate Others
    1,2-Dimethylimidazole is a pharmaceutical raw material and intermediate containing nitrogen-containing group .
    1,2-Dimethylimidazole
  • HY-W010540
    4,5-Dimethylthiazole

    		Drug Intermediate Others
    4,5-Dimethylthiazole is a nitrogen-containing heterocyclic compound. 4,5-Dimethylthiazole can be used in the synthesis of other active compounds .
    4,5-Dimethylthiazole
  • HY-W015966
    3-Methylpyrrole

    		Drug Derivative Metabolic Disease
    3-Methylpyrrole is a pyrrole-type nitrogen-containing heterocyclic aromatic compound. 3-Methylpyrrole can be used as a negative control tool for hexosamine detection .
    3-Methylpyrrole
  • HY-Y0689
    Thiocarbonyldiimidazole

    		MOFs Others
    Thiocarbonyldiimidazole is a synthetic chemical reagent that serves as a nitrogen-containing MOF ligand for synthetic applications. Thiocarbonyldiimidazole enables the preparation of thiocarbonyl imidazolides from alcohols, and is used in the Barton-McCombie deoxygenation reaction and natural product synthesis .
    Thiocarbonyldiimidazole
  • HY-Y0519R
    Pyrimidine (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease
    Pyrimidine (Standard) is the analytical standard of Pyrimidine. This product is intended for research and analytical applications. Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .
    Pyrimidine (Standard)
  • HY-W013040S
    Pyrazine-d4

    1,4-Diazine-d4

    		 Endogenous Metabolite Others
    Pyrazine-d4 is the deuterium labeled Pyrazine . Pyrazine is an aromatic nitrogen-containing heterocyclic compound with two nitrogen atoms, and is well known for its electron-deficient property. Pyrazine serves as a key pharmacophore in a variety of drugs, and also acts as the core skeleton of derivatives with anticancer, antimycobacterial, antithrombotic and anti-inflammatory activities.
    Pyrazine-d4
  • HY-19773
    β-Lactamase-IN-1

    		Beta-lactamase Bacterial Infection
    β-Lactamase-IN-1 is an inhibitor of β-Lactamase extracted from patent WO2016027249A1, page 77. β-Lactamase-IN-1 can be used to prepare of tricyclic nitrogen containing compound. β-Lactamase-IN-1 can be used for the research of neisseria gonorrhea infection .
    β-Lactamase-IN-1
  • HY-133644
    Tribromoacetonitrile

    		Drug Derivative Others
    Tribromoacetonitrile is a nitrogen-containing disinfection byproduct .
    Tribromoacetonitrile
  • HY-59024
    δ-Carboline

    		Drug Intermediate Infection Cancer
    δ-Carboline is a nitrogen-containing heterocyclic compound, and its derivatives all exhibit anti-cancer and antibacterial activities .
    δ-Carboline
  • HY-W018561
    Bis(4-octylphenyl)amine

    p,p'-Dioctyldiphenylamine; 4,4'-Dioctyldiphenylamine; DODPA

    		 Biochemical Assay Reagents Reactive Oxygen Species (ROS) Others
    Bis(4-octylphenyl)amine is an nitrogen-containing anthropogenic organic contaminant. Bis(4-octylphenyl)amine can be used as a high-temperature antioxidant additive in lubricants .
    Bis(4-octylphenyl)amine
  • HY-32828
    3-Amino-5-bromo-2-chloropyridine

    		Biochemical Assay Reagents Drug Intermediate Others
    3-Amino-5-bromo-2-chloropyridine is a nitrogen-containing heterocyclic organic compound. 3-Amino-5-bromo-2-chloropyridine is an important intermediate, which can be used for the synthesis of other active compounds .
    3-Amino-5-bromo-2-chloropyridine
  • HY-177079S
    Dazodeunetant

    		Neurokinin Receptor Neurological Disease
    Dazodeunetant (Example 56) is a nitrogen-containing fused ring derivative. Dazodeunetant is an inhibitor of neurokinin (NK). Dazodeunetant has an IC50 0f 75.99 nM against NK3R in HEK293-NK3 (IP1). Dazodeunetant can be studied in research for menopausal hot flashes .
    Dazodeunetant
  • HY-121348
    Ficellomycin

    U-47929

    		 Antibiotic Bacterial DNA/RNA Synthesis Infection
    Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases .
    Ficellomycin
  • HY-W779244
    1H-Pyrazole-3,4,5-d3

    		Isotope-Labeled Compounds Biochemical Assay Reagents Drug Intermediate Infection
    1H-Pyrazole-3,4,5-d3 is the deuterium labeled 1H-pyrazole (HY-76228). 1H-pyrazole is a nitrogen-containing heterocyclic compound composed of a five-membered ring and two nitrogen atoms. 1H-pyrazole is an intermediate in organic synthesis. 1H-pyrazole coordinates with metal ions. 1H-pyrazole derivatives have antibacterial, anti-inflammatory, anti-malarial, and anti-leishmanial activities .
    1H-Pyrazole-3,4,5-d3
  • HY-144366
    P-gp inhibitor 3

    		P-glycoprotein Cancer
    P-gp inhibitor 3 is an effective P-glycoprotein (P-gp) inhibitor. P-gp inhibitor 3 inhibits the efflux function of P-gp by activating P-gp ATPase. P-gp inhibitor 3 has relatively stronger multidrug resistance (MDR) reversal ability and enhances the anti-tumor activity of Paclitaxel .
    P-gp inhibitor 3
  • HY-133643
    Bromodichloroacetonitrile

    		Biochemical Assay Reagents Others
    Bromodichloroacetonitrile is a nitrogen-containing disinfection byproduct .
    Bromodichloroacetonitrile
  • HY-143583
    ATX inhibitor 10

    		Phosphodiesterase (PDE) Neurological Disease Cancer
    ATX inhibitor 10 is a potent inhibitor of ATX. ATX inhibitor 10 is s nitrogen-containing heterocyclic compound. ATX plays a role in causing pathological conditions including fibrosis, arthritis, neurodegeneration, neuropathic pain, and cancer. ATX inhibitor 10 has the potential for the research of ATX related diseases (extracted from patent WO2021115375A1, compound 35) .
    ATX inhibitor 10
  • HY-N14679
    Pinselin

    		Antibiotic Fungal Infection
    Pinselin is a nitrogen-containing heterocyclic antibiotic. Pinselin has anti-yeast activity .
    Pinselin
  • HY-U00393
    Arrhythmic-Targeting Compound 1

    		Others Cardiovascular Disease
    Arrhythmic-Targeting Compound 1 is used for the research of arrhythmic disease, with nitrogen-containing spirocycles.
    Arrhythmic-Targeting Compound 1
  • HY-N14587
    Oxypyrrolnitrin

    		Antibiotic Bacterial Infection
    Oxypyrrolnitrin is a nitrogen-containing heterocyclic antibiotic. Oxypyrrolnitrin has anti-Gram-positive bacteria, negative bacteria, mycobacterium and fungal effects .
    Oxypyrrolnitrin
  • HY-B0515AS1
    Ibandronic acid-d3

    		Apoptosis Isotope-Labeled Compounds Cancer
    Ibandronic acid-d3 is the deuterium labeled Ibandronic acid. Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
    Ibandronic acid-d3
  • HY-B0515AS
    Ibandronic Acid-d3 sodium salt

    		Apoptosis Isotope-Labeled Compounds Cancer
    Ibandronic Acid-d3 (sodium) is the deuterium labeled Ibandronic acid. Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis[1][2].
    Ibandronic Acid-d3 sodium salt
  • HY-108685S
    Alendronate-d4 sodium

    Alendronic acid-d4 monosodium salt

    		 Isotope-Labeled Compounds Metabolic Disease Cancer
    Alendronate-d4 (sodium) (Alendronic acid-d4 (monosodium salt)) is deuterium labeled Alendronate sodium. Alendronate sodium is an orally active nitrogen-containing bisphosphonate. Alendronate sodium potently inhibits bone resorption. Alendronate sodium is used for the research of postmenopausal osteoporosis .
    Alendronate-d4 sodium
  • HY-D2989
    BG-NH2-Ac-N3

    SNAP-NH2-Ac-N3

    		 Biochemical Assay Reagents Others
    BG-NH2-Ac-N3 (SNAP-NH2-Ac-N3) is a nitrogen-containing SNAP tag with a nitro group. BG-NH2-Ac-N3 can be used for click chemistry labeling .
    BG-NH2-Ac-N3
  • HY-W034576
    Hexacyclen hexahydrochloride

    Hexaaza-18-crown-6 hexahydrochloride; 1,4,7,10,13,16-Hexaazacyclooctadecane hexahydrochloride

    		 Biochemical Assay Reagents Cancer
    Hexacyclen (Cycloalkene) is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. Hexacyclen is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions, and is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Hexacyclen also acts as an inhibitor of cancer .
    Hexacyclen hexahydrochloride
  • HY-W002016R
    Phthalazine (Standard)

    		Reference Standards Reactive Oxygen Species (ROS) Cancer
    Phthalazine (Standard) is the analytical standard of Phthalazine. This product is intended for research and analytical applications. Phthalazine is a substrate for human aldehyde oxidase 1, which can lead to the production of ROS and subsequent enzyme inactivation. Phthalazine is a nitrogen-containing organic heterocyclic compound. Phthalazine exhibits antitumor activity in blood cancer, breast cancer, colon cancer, lung cancer and renal cancer .
    Phthalazine (Standard)
  • HY-135593
    LY88074 analog 1

    		Others Endocrinology
    LY88074 analog 1 is a benzothiophene compound with nitrogen-containing non-basic side chains, Compound 26, extracted from patent EP0747380A1. LY88074 analog 1 is an agent for alleviating the symptoms of post-menopausal symptoms, such as osteoporosis, cardiovascular related pathological conditions, and estrogen-dependent cancer. LY88074 analog 1 can be used alone or in combination with estrogen or progestin .
    LY88074 analog 1
  • HY-126854R
    N-Acetyllactosamine (Standard)

    N-Acetyl-D-lactosamine (Standard)

    		 Reference Standards Endogenous Metabolite Galectin Others
    N-Acetyllactosamine (Standard) is the analytical standard of N-Acetyllactosamine. This product is intended for research and analytical applications. N-Acetyllactosamine (N-Acetyl-D-lactosamine), a nitrogen-containing disaccharide, is a galectin-3 inhibitor, which is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects[1][2][3][4].
    N-Acetyllactosamine (Standard)
  • HY-W034566A
    Hexacyclen trisulfate

    Hexaaza-18-crown-6 trisulfate; 1,4,7,10,13,16-Hexaazacyclooctadecane trisulfate

    		 Biochemical Assay Reagents Others
    Hexacyclen, also known as cycloalkene, is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. It is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions. Inhibitors of certain diseases such as cancer. In biochemistry, Hexacyclen is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Due to its large size and complex structure, Hexacyclen is not widely used in daily products or applications.
    Hexacyclen trisulfate

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