Pamidronic acid sodium

Pamidronic acid sodium, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronic acid sodium significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronic acid sodium can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma.

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  • CAS. Nr.: 89131-02-2
  • Formel: C3H10NNaO7P2
  • Molecular Weight:257.05
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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