Ibandronic acid

Cat. No.: HY-B0515A: Data Sheet Handling Instructions
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Ibandronic acid is a highly effective nitrogen-containing bisphosphonate that can be used for osteoporosis.

For research use only. We do not sell to patients.

Ibandronic acid Chemical Structure

CAS No. : 114084-78-5

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This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of Ibandronic acid:

Ibandronate Sodium Monohydrate Ibandronate Sodium

Other Forms of Ibandronic acid:

1 Publications Citing Use of MCE Ibandronic acid

•Int J Parasitol Drugs Drug Resist. 2025 Aug 6:29:100607. [Abstract]

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Biological Activity
Purity & Documentation
References
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Description

Ibandronic acid is a highly effective nitrogen-containing bisphosphonate that can be used for osteoporosis.

Cellular Effect

Cell Line	Type	Value	Description	References
HFF	IC₅₀	54.92 μM Compound: 30	In vitro inhibitory concentration against the growth of Toxoplasma gondii in human foreskin fibroblast monolayer cells (HFF cells) In vitro inhibitory concentration against the growth of Toxoplasma gondii in human foreskin fibroblast monolayer cells (HFF cells)	[PMID: 15857119]
T-cell	EC₅₀	1 μM Compound: Ibandronate	Effective concentration to activate gammadelta T cells Effective concentration to activate gammadelta T cells	[PMID: 12383012]
T-cell	IC₅₀	31 μM Compound: 26	Inhibitory activity, for stimulation of TNF-alpha release in gamma-delta T cells, using a constrained maximum TNF-alpha release of 2700 pg/mL Inhibitory activity, for stimulation of TNF-alpha release in gamma-delta T cells, using a constrained maximum TNF-alpha release of 2700 pg/mL	[PMID: 14711309]
T-cell	IC₅₀	31 μM Compound: 26	Inhibitory activity, for stimulation of TNF-alpha release in gamma-delta T cells, using individual observed maximum TNF-alpha release Inhibitory activity, for stimulation of TNF-alpha release in gamma-delta T cells, using individual observed maximum TNF-alpha release	[PMID: 14711309]

Clinical Trial

Molecular Weight

319.23

Formula

C₉H₂₃NO₇P₂

CAS No.

114084-78-5

SMILES

OC(P(O)(O)=O)(P(O)(O)=O)CCN(C)CCCCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Morgan, C., S. Jeremiah, and J. Wagstaff, Metronomic administration of ibandronate and its anti-angiogenic effects in vitro. Microvasc Res, 2009. 78(3): p. 453-8. [Content Brief]

[2]. Epplen, R., et al., Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines. Acta Oncol, 2011. 50(1): p. 127-33. [Content Brief]

[3]. Chesnut, I.C., et al., Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis. J Bone Miner Res, 2004. 19(8): p. 1241-9. [Content Brief]

[4]. Bauss, F., et al., Effects of treatment with ibandronate on bone mass, architecture, biomechanical properties, and bone concentration of ibandronate in ovariectomized aged rats. J Rheumatol, 2002. 29(10): p. 2200-8. [Content Brief]

Ibandronic acid Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ibandronic acid114084-78-5OthersInhibitorinhibitorinhibit

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