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Results for "

ala-ala-

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (20) Amino Acid Derivatives (8) Aminopeptidase (1) Apoptosis (4) Autophagy (3) Bacterial (1) Biochemical Assay Reagents (1) Carnosine-cleaving Enzyme (1) Caspase (2) Dopamine Receptor (1) Drug-Linker Conjugates for ADC (7) Elastase (5) Endogenous Metabolite (10) Fluorescent Dye (7) Glucocorticoid Receptor (5) Interleukin Related (1) Isotope-Labeled Compounds (3) Kinesin (1) Liposome (1) Mitophagy (3) Parasite (2) PKC (1) Prolyl Endopeptidase (PREP) (1) Proteasome (3) Reactive Oxygen Species (ROS) (3) Reference Standards (3) Ser/Thr Protease (2) TNF Receptor (2) Topoisomerase (1) TRP Channel (1)
By Research Areas:	Cancer (30) Cardiovascular Disease (3) Endocrinology (1) Infection (3) Inflammation/Immunology (12) Metabolic Disease (4) Neurological Disease (3)
Click Chemistry:	ADC Synthesis (1) Azide (2)

Inhibitors & Agonists

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Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1247

Protoporphyrin IX Maximum Cited Publications 22 Publications Verification PPIX	Endogenous Metabolite	Others
Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-N0305

5-Aminolevulinic acid hydrochloride 15+ Cited Publications 5-ala hydrochloride; δ-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid hydrochloride	Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) hydrochloride is an orally active heme precursor. 5-Aminolevulinic acid hydrochloride promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid hydrochloride enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid hydrochloride selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid hydrochloride can be applied to the research of septic shock, melanoma, and cancer radiotherapy .

HY-136626

*Z-Ala-Ala-Asn-AMC* 3 Publications Verification Cbz-ala-ala-Asn-AMC	Fluorescent Dye	Cancer
Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC .

HY-W000450

5-Aminolevulinic acid 15+ Cited Publications 5-ala; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid	Reactive Oxygen Species (ROS)	Cardiovascular Disease Cancer
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) is an orally active heme precursor. 5-Aminolevulinic acid promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid can be applied to the research of septic shock, melanoma, and cancer radiotherapy .

HY-148462

*Fmoc-Ala-Ala-PAB*	ADC Linker	Cancer
Fmoc-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-148464

*MC-Ala-Ala-PAB*	ADC Linker	Cancer
MC-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W048825

*Fmoc-Ala-Ala-OH*	Amino Acid Derivatives	Others
Fmoc-Ala-Ala-OH is a self-assembling fluorenylmethoxycarbonyl dipeptide, a small amphiphilic building block composed of a dipeptide linked to a fluorenylmethoxycarbonyl (Fmoc) group. Under conditions of pH < 4, Fmoc-Ala-Ala-OH spontaneously assembles to form a nanofiber network, constructing a hydrogel scaffold with a water content exceeding 99% (w/w). The fibers have a diameter of approximately 22 nm, matching the size of extracellular matrix (ECM) components. Fmoc-Ala-Ala-OH supports cell adhesion, proliferation, and maintains of cell phenotype. Fmoc-Ala-Ala-OH's function is to mimic the ECM, providing a 3D growth microenvironment for cells, and Fmoc-Ala-Ala-OH is primarily used in tissue engineering and 3D cell culture, particularly suitable for in vitro culture studies of cells such as chondrocytes[1] .

HY-P2685

*MeOSuc-Ala-Ala-Pro-Val-pNA*	Fluorescent Dye	Others
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .

HY-W010162

*H-Ala-Ala-OH* L-alanyl-L-alanine; ala-ala	Amino Acid Derivatives	Others
H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) is a nonpolar dipeptide that is absorbed by human intestinal Caco-2 cells. The transport of alanine (Ala), like proton/amino acid symport, can lead to cytoplasmic acidification .

HY-P10004

*Z-Ala-Ala-Asp-CMK* 2 Publications Verification Z-AAD-CMK	Caspase Apoptosis Reactive Oxygen Species (ROS) Interleukin Related	Inflammation/Immunology Cancer
Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor. By binding to the active site of granzyme B, Z-Ala-Ala-Asp-CMK blocks its proteolytic function. Z-Ala-Ala-Asp-CMK has anti-inflammatory activity and can be used in the research of inflammatory diseases and cancer .

HY-153345

*Glucocorticoid receptor agonist-1 phosphate(2,6-difluoro) Ala-Ala-Br*	Drug-Linker Conjugates for ADC Glucocorticoid Receptor	Inflammation/Immunology
Glucocorticoid receptor agonist-1 phosphate(2,6-difluoro) Ala-Ala-Br is an Drug-linker conjugates for ADC that can be used as a reaction reagent for the synthesis of anti-CD40 antibody agent conjugates (ADCs) .

HY-152121

*Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal*	Glucocorticoid Receptor Drug-Linker Conjugates for ADC	Infection Inflammation/Immunology
Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal is a glucocorticoid receptor agonist. Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal can be used in anti-CD40 antibody agent conjugate (ADC). Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal can be used for the research of inflammation and immune regulation .

HY-137882

*Glucocorticoid receptor agonist-1 Ala-Ala-Mal*	Drug-Linker Conjugates for ADC Glucocorticoid Receptor	Inflammation/Immunology
Glucocorticoid receptor agonist-1 Ala-Ala-Mal (compound 88) is a glucocorticosteroid, and an agonist of glucocorticoid receptor. Glucocorticoid receptor agonist-1 Ala-Ala-Mal can be conjugated with Adalimumab (HY-P9908) to prepare an ADC .

HY-148436

*Glucocorticoid receptor agonist-2 Ala-Ala-Mal*	Drug-Linker Conjugates for ADC	Inflammation/Immunology
Glucocorticoid receptor agonist-2 Ala-Ala-Mal (compound 79) can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference for ABBV-3373 .

HY-133803

*Z-Ala-Ala-OH*	Amino Acid Derivatives	Others
Z-Ala-Ala-OH is an N-benzyloxycarbonyl (Z) dipeptide containing small nonpolar amino acids. Z-Ala-Ala-OH is used for enzymatic peptide synthesis .

HY-W039756

*Boc-Ala-Ala-OH* NSC 334362	Amino Acid Derivatives	Others
Boc-Ala-Ala-OH (NSC 334362) is an Alanine derivative. Boc-Ala-Ala-OH is used in the preparation of anti-bacterial agent .

HY-P4453

*Boc-Ala-Ala-Asp-pNA*	Caspase	Cancer
Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .

HY-B1247R

Protoporphyrin IX (Standard) PPIX (Standard)	Reference Standards Endogenous Metabolite	Others
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-P5994

MeOSuc-AAPF-CMK MeOSuc-ala-ala-Pro-Phe-CH₂Cl	Ser/Thr Protease	Others
MeOSuc-AAPF-CMK (MeOSuc-Ala-Ala-Pro-Phe-CH Cl) is a potent proteinase K inhibitor .

HY-P3106

*(Z-Ala-Ala-Ala-Ala)2Rh110* (Z-ala-ala-ala-ala)2Rhodamine110; bis-CBZ-L-alanyl-L-arginine amide Rhodamine 110	Fluorescent Dye	Others
(Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.

HY-P3558

Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met	Amino Acid Derivatives	Others
Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met

HY-137337

*Suc-Ala-Ala-Phe-AMC*	Fluorescent Dye	Others
Suc-Ala-Ala-Phe-AMC is a fluorogenic chymotrypsin substrate, can be hydrolyzed by endopeptidase. Suc-Ala-Ala-Phe-AMC has been used in both in vivo assays of the acrosome reaction and in vitro enzyme assays .

HY-129360

Ala-Ala-Asn-PAB	ADC Linker	Cancer
Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs) .

HY-P4582

*Suc-Phe-Ala-Ala-Phe-pNA* Suc-FAAF-pNA	Ser/Thr Protease	Others
Suc-Phe-Ala-Ala-Phe-pNA (Suc-FAAF-pNA) is a chromogenic polypeptide substrate that can be used for the quantitative activity assay of intracellular subtilisin (ISP) and neutral metalloprotease (NPS) derived from Saccharomonospora canescens. Suc-Phe-Ala-Ala-Phe-pNA is hydrolyzed by the catalytic triad of mature proteases to release the chromophore pNA. Suc-Phe-Ala-Ala-Phe-pNA is applicable to enzymological studies .

HY-P2648

*Suc-Ala-Ala-Pro-Leu-pNA* N-Succinyl-AAPL-p-nitroanilide	Aminopeptidase	Endocrinology
Suc-Ala-Ala-Pro-Leu-pNA (N-Succinyl-AAPL-p-nitroanilide) is a tripeptidyl p-nitroanilide substrate that can be catalytically hydrolyzed by acyl amidase-like leucine aminopeptidase in seminal plasma. Amastatin (HY-129298) and Actinonin (HY-113952) exert potent inhibitory effects on this hydrolytic activity. Suc-Ala-Ala-Pro-Leu-pNA can be used for the research of diseases such as azoospermia .

HY-133100

5-ALA benzyl ester hydrochloride Benzyl-ala hydrochloride	Endogenous Metabolite	Cancer
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines .

HY-N0305S

5-Aminolevulinic acid-15N hydrochloride 5-ala-15N hydrochloride; δ-Aminolevulinic acid-15N hydrochloride; 5-Amino-4-oxopentanoic acid-15N hydrochloride	Isotope-Labeled Compounds Autophagy Mitophagy Endogenous Metabolite Apoptosis	Metabolic Disease Cancer
5-Aminolevulinic acid- ¹⁵N (hydrochloride) is the ¹⁵N-labeled 5-Aminolevulinic acid (hydrochloride). 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.

HY-148463

*MP-Ala-Ala-PAB*	ADC Linker	Cancer
MP-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W749251

5-Aminolevulinic acid-13C2,15N hydrochloride 5-ala-13C2,15N hydrochloride; δ-Aminolevulinic acid-13C2,15N hydrochloride; 5-Amino-4-oxopentanoic acid-13C2,15N hydrochloride	Endogenous Metabolite Isotope-Labeled Compounds	Others
5-Aminolevulinic acid- ¹³C₂, ¹⁵N (5-ALA- ¹³C₂, ¹⁵N; δ-Aminolevulinic acid- ¹³C₂, ¹⁵N) is ¹³C- and ¹⁵N-labeled 5-Aminolevulinic acid (HY-W000450) .

HY-P4126

*Suc-Ala-Ala-Pro-Val-AMC*	Elastase	Others
Suc-Ala-Ala-Pro-Val-AMC is a fluorescent substrate for elastase. Suc-Ala-Ala-Pro-Val-AMC can be hydrolyzed by these elastases to release the fluorescent substance 7-amino-4-methylcoumarin. Suc-Ala-Ala-Pro-Val-AMC is used for in vitro elastase activity assays and can also be applied in studies related to chronic wounds .

HY-129361

*Fmoc-Ala-Ala-Asn-PABC-PNP*	ADC Linker	Cancer
Fmoc-Ala-Ala-Asn-PABC-PNP is a peptide cleavable ADC linker .

HY-P4580

*Suc-Ala-Ala-Pro-Phe-SBzl*	Proteasome	Others
Suc-Ala-Ala-Pro-Phe-SBzl can be used as the substrate of rat intestinal mast cell protease (RMCP I), rat skeletal muscle mast cell protease (RMCP II) and Chymotrypsin (HY-108910). Suc-Ala-Ala-Pro-Phe-SBzl can be hydrolyzed by glycine (R208G) .

HY-178145

*Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan (compound 12) is a Drug-Linker Conjugate for ADC. Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan contains the ADC linker (Mc-Lys(PEG12)-Cap-Ala-Ala-PABC) (HY-178146) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan can be used for the development of ADC targeting HER2-positive breast cancer .

HY-B1247A

Protoporphyrin IX disodium Maximum Cited Publications 22 Publications Verification PPIX disodium	Endogenous Metabolite	Cancer
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX disodium also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX disodium is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX disodium causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX disodium is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-W010162R

*H-Ala-Ala-OH (Standard)* L-alanyl-L-alanine (Standard); ala-ala (Standard)	Amino Acid Derivatives Reference Standards	Others
H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) (Standard) is the analytical standard of H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala). This product is intended for research and analytical applications. H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) is a nonpolar dipeptide that is absorbed by human intestinal Caco-2 cells. The transport of alanine (Ala), like proton/amino acid symport, can lead to cytoplasmic acidification .

HY-P3741

[Ala9,10, Lys11,12] Glycogen Synthase (1-12)	PKC	Neurological Disease
[Ala9,10, Lys11,12] Glycogen Synthase (1-12) is a selective substrate for phosphorylation by protein kinase C (PKC). [Ala9,10, Lys11,12] Glycogen Synthase (1-12) can be used to determine the activity of protein kinase C .

HY-139245

*MC-Ala-Ala-Asn-PAB*	ADC Linker	Cancer
MC-Ala-Ala-Asn-PAB is a linker extracted from patent CN104147612A, page 14. MC-Ala-Ala-Asn-PAB can be used to synthesis the tumor microenvironment specific activated micromolecular targeted conjugate .

HY-137164

Ala-Ala-Phe-AMC	Endogenous Metabolite	Others
Ala-Ala-Phe-AMC serves as a fluorogenic substrate that exhibits positively charged properties, making it suitable for assessing proteolytic activity.

HY-139856

*Mal-Ala-Ala-PAB-PNP*	ADC Linker	Cancer
Mal-Ala-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-136705

*MeO-Suc-Ala-Ala-Pro-Ala-CMK* MSACK	Elastase	Inflammation/Immunology
MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE), with an IC₅₀ of 20.3 μM. MeO-Suc-Ala-Ala-Pro-Ala-CMK can inhibit the hydrolysis of substrates such as elastin in lung tissue by HNE. MeO-Suc-Ala-Ala-Pro-Ala-CMK can be used in the research of related diseases such as chronic obstructive pulmonary disease (COPD) .

HY-160180

*Glucocorticoid receptor agonist-4 Ala-Ala-Mal*	TNF Receptor Glucocorticoid Receptor Drug-Linker Conjugates for ADC	Inflammation/Immunology
Glucocorticoid receptor agonist-4 Ala-Ala-Mal (Compound Preparation 9) is an anti-human TNFα antibody-glucocorticoid receptor agonist (GC) conjugate. Glucocorticoid receptor agonist-4 Ala-Ala-Mal can be used in the study of autoimmune and inflammatory diseases .

HY-130933

*Fmoc-Ala-Ala-Asn(Trt)-OH*	ADC Linker	Cancer
Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-157338

*NHS-Ala-Ala-Asn-active metabolite*	ADC Linker Kinesin	Cancer
NHS-Ala-Ala-Asn-active metabolite is a cleavable antibody-drug conjugate (ADC) linker for synthesis of kinesin spindle protein (KSP)inhibitor .

HY-P3648

Ala-Ala-Pro-Val-chloromethylketone AAPV-CMK	Elastase	Inflammation/Immunology
Ala-Ala-Pro-Val-chloromethylketone is an irreversible human neutrophil elastase (NE) inhibitor for use in the study of chronic inflammatory airway diseases .

HY-178146

*Mc-Lys(PEG12)-Cap-Ala-Ala-PABC*	ADC Linker	Cancer
Mc-Lys(PEG12)-Cap-Ala-Ala-PABC is a linker of MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (HY-178146) .

HY-P4353

*D-{Ala-Ala-Ala}*	Bacterial	Others
D-{Ala-Ala-Ala} is a tripeptide. D-{Ala-Ala-Ala} binds to ristocetin to detect bacteria at low concentrations .

HY-W013460

*Ala-Ala-Ala*	Amino Acid Derivatives	Others
Ala-Ala-Ala is an alanine derivative .

HY-P4350

*Suc-Ala-Ala-Ala-AMC*	Elastase	Others
Suc-Ala-Ala-Ala-AMC is a peptide substrate of elastase or elastase-like .

HY-N0305S3

5-Aminolevulinic acid-13C-1 hydrochloride 5-ala-13C-1 hydrochloride; δ-Aminolevulinic acid-13C-1 hydrochloride; 5-Amino-4-oxopentanoic acid-13C-1 hydrochloride	Apoptosis Autophagy Mitophagy Endogenous Metabolite	Metabolic Disease
5-Aminolevulinic acid- ¹³C-1 (5-ALA- ¹³C-1) hydrochloride is the ¹³C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .

HY-160714

*Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH*	ADC Linker	Cancer
Fmoc-Ala-Ala-Ala-amide-C-O-C-COOH (Compound IM-3) is a cleavable ADC linker .

Cat. No.	Product Name	Type

HY-W010162

*H-Ala-Ala-OH* L-alanyl-L-alanine; ala-ala	Biochemical Assay Reagents
H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) is a nonpolar dipeptide that is absorbed by human intestinal Caco-2 cells. The transport of alanine (Ala), like proton/amino acid symport, can lead to cytoplasmic acidification .

HY-W010162R

H-Ala-Ala-OH (Standard)

L-alanyl-L-alanine (Standard); ala-ala (Standard)

Biochemical Assay Reagents

H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) (Standard) is the analytical standard of H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala). This product is intended for research and analytical applications. H-Ala-Ala-OH (L-Alanyl-L-alanine; Ala-Ala) is a nonpolar dipeptide that is absorbed by human intestinal Caco-2 cells. The transport of alanine (Ala), like proton/amino acid symport, can lead to cytoplasmic acidification .

HY-137164

Ala-Ala-Phe-AMC	Biochemical Assay Reagents
Ala-Ala-Phe-AMC serves as a fluorogenic substrate that exhibits positively charged properties, making it suitable for assessing proteolytic activity.

Cat. No.	Product Name	Target	Research Area

HY-P2573

Suc-AAPF-pNA 2 Publications Verification Suc-ala-ala-Pro-Phe-pNA	Peptides	Others
Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the K_m of 1.7 mM. Cleavage of Suc-AAPF-pNA releases 4-nitroaniline, which is yellow in colour and can be measured spectrophotometrically. Suc-AAPF-pNA can be used for the measurement of free and membrane-bound cathepsin G in human neutrophils .

HY-136626

*Z-Ala-Ala-Asn-AMC* 3 Publications Verification Cbz-ala-ala-Asn-AMC	Fluorescent Dye	Cancer
Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC .

HY-W048825

*Fmoc-Ala-Ala-OH*	Amino Acid Derivatives	Others
Fmoc-Ala-Ala-OH is a self-assembling fluorenylmethoxycarbonyl dipeptide, a small amphiphilic building block composed of a dipeptide linked to a fluorenylmethoxycarbonyl (Fmoc) group. Under conditions of pH < 4, Fmoc-Ala-Ala-OH spontaneously assembles to form a nanofiber network, constructing a hydrogel scaffold with a water content exceeding 99% (w/w). The fibers have a diameter of approximately 22 nm, matching the size of extracellular matrix (ECM) components. Fmoc-Ala-Ala-OH supports cell adhesion, proliferation, and maintains of cell phenotype. Fmoc-Ala-Ala-OH's function is to mimic the ECM, providing a 3D growth microenvironment for cells, and Fmoc-Ala-Ala-OH is primarily used in tissue engineering and 3D cell culture, particularly suitable for in vitro culture studies of cells such as chondrocytes[1] .

HY-P2685

*MeOSuc-Ala-Ala-Pro-Val-pNA*	Fluorescent Dye	Others
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .

HY-P10004

*Z-Ala-Ala-Asp-CMK* 2 Publications Verification Z-AAD-CMK	Caspase Apoptosis Reactive Oxygen Species (ROS) Interleukin Related	Inflammation/Immunology Cancer
Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor. By binding to the active site of granzyme B, Z-Ala-Ala-Asp-CMK blocks its proteolytic function. Z-Ala-Ala-Asp-CMK has anti-inflammatory activity and can be used in the research of inflammatory diseases and cancer .

HY-W039756

*Boc-Ala-Ala-OH* NSC 334362	Amino Acid Derivatives	Others
Boc-Ala-Ala-OH (NSC 334362) is an Alanine derivative. Boc-Ala-Ala-OH is used in the preparation of anti-bacterial agent .

HY-P4621

L-Alanyl-L-alanyl-L-glutamine H-ala-ala-Gln-OH; ala-ala-Gln	Peptides	Others
Ala-Ala-Gln is a peptide. Ala-Ala-Gln can be used for various biochemical studies .

HY-137811

Suc-AAPF-AMC 2 Publications Verification Suc-ala-ala-Pro-Phe-AMC	Peptides	Others
Suc-AAPF-AMC is an α-chymotrypsin fluorogenic substrate for the quantitative determination of chymotrypsin activity .

HY-P4453

*Boc-Ala-Ala-Asp-pNA*	Caspase	Cancer
Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .

HY-P5994

MeOSuc-AAPF-CMK MeOSuc-ala-ala-Pro-Phe-CH₂Cl	Ser/Thr Protease	Others
MeOSuc-AAPF-CMK (MeOSuc-Ala-Ala-Pro-Phe-CH Cl) is a potent proteinase K inhibitor .

HY-P3106

*(Z-Ala-Ala-Ala-Ala)2Rh110* (Z-ala-ala-ala-ala)2Rhodamine110; bis-CBZ-L-alanyl-L-arginine amide Rhodamine 110	Fluorescent Dye	Others
(Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.

HY-P3558

Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met	Amino Acid Derivatives	Others
Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Met

HY-137337

*Suc-Ala-Ala-Phe-AMC*	Fluorescent Dye	Others
Suc-Ala-Ala-Phe-AMC is a fluorogenic chymotrypsin substrate, can be hydrolyzed by endopeptidase. Suc-Ala-Ala-Phe-AMC has been used in both in vivo assays of the acrosome reaction and in vitro enzyme assays .

HY-P4582

*Suc-Phe-Ala-Ala-Phe-pNA* Suc-FAAF-pNA	Ser/Thr Protease	Others
Suc-Phe-Ala-Ala-Phe-pNA (Suc-FAAF-pNA) is a chromogenic polypeptide substrate that can be used for the quantitative activity assay of intracellular subtilisin (ISP) and neutral metalloprotease (NPS) derived from Saccharomonospora canescens. Suc-Phe-Ala-Ala-Phe-pNA is hydrolyzed by the catalytic triad of mature proteases to release the chromophore pNA. Suc-Phe-Ala-Ala-Phe-pNA is applicable to enzymological studies .

HY-P2648

*Suc-Ala-Ala-Pro-Leu-pNA* N-Succinyl-AAPL-p-nitroanilide	Aminopeptidase	Endocrinology
Suc-Ala-Ala-Pro-Leu-pNA (N-Succinyl-AAPL-p-nitroanilide) is a tripeptidyl p-nitroanilide substrate that can be catalytically hydrolyzed by acyl amidase-like leucine aminopeptidase in seminal plasma. Amastatin (HY-129298) and Actinonin (HY-113952) exert potent inhibitory effects on this hydrolytic activity. Suc-Ala-Ala-Pro-Leu-pNA can be used for the research of diseases such as azoospermia .

HY-P4126

*Suc-Ala-Ala-Pro-Val-AMC*	Elastase	Others
Suc-Ala-Ala-Pro-Val-AMC is a fluorescent substrate for elastase. Suc-Ala-Ala-Pro-Val-AMC can be hydrolyzed by these elastases to release the fluorescent substance 7-amino-4-methylcoumarin. Suc-Ala-Ala-Pro-Val-AMC is used for in vitro elastase activity assays and can also be applied in studies related to chronic wounds .

HY-P4580

*Suc-Ala-Ala-Pro-Phe-SBzl*	Proteasome	Others
Suc-Ala-Ala-Pro-Phe-SBzl can be used as the substrate of rat intestinal mast cell protease (RMCP I), rat skeletal muscle mast cell protease (RMCP II) and Chymotrypsin (HY-108910). Suc-Ala-Ala-Pro-Phe-SBzl can be hydrolyzed by glycine (R208G) .

HY-P4357

*D-{Ala-Ala-Ala-Ala-Ala}*	Peptides	Inflammation/Immunology
D-{Ala-Ala-Ala-Ala-Ala} is a pentapeptide and can be used as an inhibitor of the immunological reactions .

HY-P4525

*Ala-Ala-Ala-Ala*	Peptides	Others
Ala-Ala-Ala-Ala is a poly-L-alanine (PLA) sequences. PLA is a kind of key element of the crystalline domains of spider dragline and wild silkworm silks .

HY-P3741

[Ala9,10, Lys11,12] Glycogen Synthase (1-12)	PKC	Neurological Disease
[Ala9,10, Lys11,12] Glycogen Synthase (1-12) is a selective substrate for phosphorylation by protein kinase C (PKC). [Ala9,10, Lys11,12] Glycogen Synthase (1-12) can be used to determine the activity of protein kinase C .

HY-P3938

*Suc-Ala-Ala-Pro-Gly-pNA*	Peptides	Others
Suc-Ala-Ala-Pro-Gly-Pna is a peptide. Suc-Ala-Ala-Pro-Gly-pNA can be used for the research of various biochemical .

HY-P3648

Ala-Ala-Pro-Val-chloromethylketone AAPV-CMK	Elastase	Inflammation/Immunology
Ala-Ala-Pro-Val-chloromethylketone is an irreversible human neutrophil elastase (NE) inhibitor for use in the study of chronic inflammatory airway diseases .

HY-P4239

H-AAAAAA-OH	Peptides	Others
Ala-Ala-Ala-Ala-Ala-Ala is a hexapeptide composed of six alanine amino acid residues .

HY-P4353

*D-{Ala-Ala-Ala}*	Bacterial	Others
D-{Ala-Ala-Ala} is a tripeptide. D-{Ala-Ala-Ala} binds to ristocetin to detect bacteria at low concentrations .

HY-W013460

*Ala-Ala-Ala*	Amino Acid Derivatives	Others
Ala-Ala-Ala is an alanine derivative .

HY-P4350

*Suc-Ala-Ala-Ala-AMC*	Elastase	Others
Suc-Ala-Ala-Ala-AMC is a peptide substrate of elastase or elastase-like .

HY-P3559

Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Leu	Peptides	Others
Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Leu is a β-lipotropin peptide. Ala-Ala-Ala-Tyr-Gly-Gly-Phe-Leu is a polypeptide of 8 amino acids .

HY-P4527

Ala-Ala-βNA	Prolyl Endopeptidase (PREP)	Others
Ala-Ala-βNA is a dipeptidyl-fl-naphthylamide (βNA). Ala-Ala-βNA is readily hydrolyzed, with optimum hydrolysis pH of 8.5-9.0 .

HY-137164A

Ala-Ala-Phe-AMC TFA	Fluorescent Dye	Others
Ala-Ala-Phe-AMC TFA is the TFA salt form for Ala-Ala-Phe-AMC. Ala-Ala-Phe-AMC TFA is a fluorogenic substrate, which is used to for tripeptidyl peptidase II (TPPII) activity determination .

HY-P4526

Ala-Ala-OMe	Peptides	Others
Ala-Ala-OMe is adipeptide derivative.

HY-P4461

Ala-Ala-Pro-pNA	Peptides	Others
Ala-Ala-Pro-pNA is a tripeptide, including chromophoric amino acids Pro-pNA. Ala-Ala-Pro-pNA is targeted by tripeptidyl aminopeptidase (SM-TAP) .

HY-P4706

*Boc-Ala-Ala-pNA*	Amino Acid Derivatives	Others
Boc-Ala-Ala-pNA is a serine peptidase

HY-P1444

Acein	Dopamine Receptor	Neurological Disease
Acein is a novel nonapeptide, H-Pro-Pro-Thr-Thr-Thr-Lys-Phe-Ala-Ala-OH. Acein can promote the release of dopamine. Acein targets angiotensin converting enzyme (ACE I). Angiotensin converting enzyme (ACE I) can be used in nervous system related research .

HY-129028

*H-Ala-Ala-Tyr-OH*	Peptides	Others
H-Ala-Ala-Tyr-OH can be synthesized mutant peptides .

HY-129028A

*H-Ala-Ala-Tyr-OH TFA*	Peptides	Others
H-Ala-Ala-Tyr-OH TFA can be synthesized mutant peptides .

HY-P4346

*MeOSuc-Ala-Ala-Pro-Met-AMC*	Elastase	Others
MeOSuc-Ala-Ala-Pro-Met-AMC is a peptide substrate of elastases and chymotrypsin-like serine peptidases .

HY-P5337

*Myristoyl tetrapeptide Ala-Ala-Pro-Val*	Peptides	Others
Myristoyl tetrapeptide Ala-Ala-Pro-Val is a biological active peptide. (stimulates the expression of ECM proteins and inhibits the expression of metalloproteinases (MMPs))

HY-148031

*MC-Ala-Ala-Asn-PAB-PNP*	ADC Linker	Others
MC-Ala-Ala-Asn-PAB-PNP is a peptide, can be used to synthesize specifically activated micromolecular target coupling body .

HY-P4355

D-Ala-Ala	Peptides	Others
D-Ala-Ala is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5993

*MeOSuc-Ala-Ala-Pro-Val-4-MNA*	Fluorescent Dye	Others
MeOSuc-Ala-Ala-Pro-Val-4-MNA is a elastase fluorogenic substrate that can be detected at 425 nm (with excitation at 340 nm) .

HY-P5996

*MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2*	Fluorescent Dye	Others
MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2 is a protein tyrosine phosphatase fluorogenic substrate that can be detected at 393 nm (with excitation at 325 nm) .

HY-P10215

*Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2*	Parasite	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .

HY-P10213

CbZ-Ala-Ala-Ala-Ala	Peptides	Others
CbZ-Ala-Ala-Ala-Ala is a modified peptide .

HY-P3939

*Suc-Ala-Ala-Pro-Trp-pNA*	Peptides	Others
Suc-Ala-Ala-Pro-Trp-Pna is a peptide. Suc-Ala-Ala-Pro-Trp-pNA can be used for the research of various biochemical.

HY-16707

CH 5450 Z-Ile-Glu-Pro-Phe-Ome	Proteasome	Inflammation/Immunology
CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC₅₀ value of 49 µM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC₅₀ value of 4.8 µM .

HY-P3423

NH2-KAA-COOH	Peptides	Cancer
NH2-KAA-COOH is a oligopeptide compoused of Lys-Ala-Ala.

HY-P3614

[Ala3,11,18, Nle7] Endothelin-1, human	Peptides	Others
[Ala3,11,18, Nle7] Endothelin-1, human is a synthetic peptide.

HY-P11735

Suc-AAPP-pNA	Peptides	Others
Suc-AAPP-pNA is a protease substrate. (Sequence: Suc-Ala-Ala-Pro-Pro-pNA) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1247

Protoporphyrin IX Maximum Cited Publications 22 Publications Verification PPIX	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-N0305

5-Aminolevulinic acid hydrochloride 15+ Cited Publications 5-ala hydrochloride; δ-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid hydrochloride	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Cancer	Reactive Oxygen Species (ROS)
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) hydrochloride is an orally active heme precursor. 5-Aminolevulinic acid hydrochloride promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid hydrochloride enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid hydrochloride selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid hydrochloride can be applied to the research of septic shock, melanoma, and cancer radiotherapy .

HY-W000450

5-Aminolevulinic acid 15+ Cited Publications 5-ala; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid	Cardiovascular Disease Structural Classification Classification of Application Fields Amino acids Endogenous metabolite Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Disease Research Fields Source Classification Cancer	Reactive Oxygen Species (ROS)
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) is an orally active heme precursor. 5-Aminolevulinic acid promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid can be applied to the research of septic shock, melanoma, and cancer radiotherapy .

HY-B1247R

Protoporphyrin IX (Standard) PPIX (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

HY-133100

5-ALA benzyl ester hydrochloride Benzyl-ala hydrochloride	Alkaloids Classification of Application Fields Other Alkaloids Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines .

HY-W014394R

Vanillyl butyl ether (Standard)	Structural Classification Monophenols other families Phenols Plants Source Classification	TRP Channel Reference Standards Parasite
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .

Cat. No.	Product Name	Chemical Structure

HY-N0305S

5-Aminolevulinic acid-15N hydrochloride
5-Aminolevulinic acid- ¹⁵N (hydrochloride) is the ¹⁵N-labeled 5-Aminolevulinic acid (hydrochloride). 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.

HY-W749251

5-Aminolevulinic acid-13C2,15N hydrochloride
5-Aminolevulinic acid- ¹³C₂, ¹⁵N (5-ALA- ¹³C₂, ¹⁵N; δ-Aminolevulinic acid- ¹³C₂, ¹⁵N) is ¹³C- and ¹⁵N-labeled 5-Aminolevulinic acid (HY-W000450) .

HY-N0305S3

5-Aminolevulinic acid-13C-1 hydrochloride
5-Aminolevulinic acid- ¹³C-1 (5-ALA- ¹³C-1) hydrochloride is the ¹³C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .

HY-W000450S

5-Aminolevulinic acid-13C
5-Aminolevulinic acid- ¹³C is the ¹³C-labeled 5-Aminolevulinic acid. 5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis.

HY-N0305S2

5-Aminolevulinic acid-13C hydrochloride
5-Aminolevulinic acid- ¹³C (hydrochloride) is the ¹³C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .

Cat. No.	Product Name		Classification

HY-141152

*Azido-PEG4-Ala-Ala-Asn(Trt)-PAB*		Azide
Azido-PEG4-Ala-Ala-Asn(Trt)-PAB is a cleavable ADC linker.

HY-141150

*Azido-PEG5-Ala-Ala-Asn-PAB*		ADC Synthesis Azide
Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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