Cbz-Ala-Ala-Asn TFA
Based on 1 Customer Validation
Cbz-Ala-Ala-Asn TFA is a peptide that designed based on the sequence of the substrate of legumain. Legumain is a cysteine protease. Cbz-Ala-Ala-Asn TFA can be applied as a scaffold for drug delivery.
For research use only. We do not sell to patients.
- Purity: 99.54%
- Formula: C20H25F3N4O9
- Molecular Weight:522.43
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 522.43
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Formula C20H25F3N4O9
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Color White to off-white
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SMILES
NC(C[C@@H](C(O)=O)NC([C@H](C)NC([C@H](C)NC(OCC1=CC=CC=C1)=O)=O)=O)=O.O=C(O)C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : 18 mg/mL (34.45 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Shan L. Cy5-labeled aza-peptidyl Pro-Asn epoxide. 2010 May 12 [updated 2010 Jun 3]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. [Content Brief]
[2]. Poreba M. Recent advances in the development of legumain-selective chemical probes and peptide prodrugs. Biol Chem. 2019 Nov 26;400(12):1529-1550. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.9141 mL | 9.5707 mL | 19.1413 mL | 47.8533 mL |
| 5 mM | 0.3828 mL | 1.9141 mL | 3.8283 mL | 9.5707 mL | |
| 10 mM | 0.1914 mL | 0.9571 mL | 1.9141 mL | 4.7853 mL | |
| 15 mM | 0.1276 mL | 0.6380 mL | 1.2761 mL | 3.1902 mL | |
| 20 mM | 0.0957 mL | 0.4785 mL | 0.9571 mL | 2.3927 mL | |
| 25 mM | 0.0766 mL | 0.3828 mL | 0.7657 mL | 1.9141 mL | |
| 30 mM | 0.0638 mL | 0.3190 mL | 0.6380 mL | 1.5951 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.