Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively.
For research use only. We do not sell to patients.
- Formula: C31H49N7O11
- Molecular Weight:695.76
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
More
Biological Activity
Description
IC50 & Target
SUB1 protease[1]
Chemical Information
-
Molecular Weight 695.76
-
Formula C31H49N7O11
-
Sequence
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2
-
Sequence Shortening
Ac-{Cpg}-TA-{Ala(CO)}-D-{Cpg}-NH2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)