Glucocorticoid receptor agonist-4 Ala-Ala-Mal 

Glucocorticoid receptor agonist-4 Ala-Ala-Mal (Compound Preparation 9) is an anti-human TNFα antibody-glucocorticoid receptor agonist (GC) conjugate. Glucocorticoid receptor agonist-4 Ala-Ala-Mal can be used in the study of autoimmune and inflammatory diseases^[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

910.98

C₄₉H₅₅FN₄O₁₂

3014393-37-1

OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@@H](C6=C(C(OCC7=CC(NC([C@H](C)NC([C@H](C)NC(CCN8C(C=CC8=O)=O)=O)=O)=O)=CC=C7)=CC=C6C)F)O2)C)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Grace CHAO, et al. Human tumor necrosis factor alpha antibody glucocorticoid conjugates. Patent WO2023220549A1.