Glucocorticoid receptor agonist-3 Ala-Ala-Mal

Name: Glucocorticoid receptor agonist-3 Ala-Ala-Mal
Brand: MedChemExpress
SKU: HY-160178
Rating: 4.5 (0 reviews)

製品番号: HY-160178 純度: 99.72%: Data Sheet SDS COA 取扱説明書
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Glucocorticoid receptor agonist-3 Ala-Ala-Mal (Compound Preparation 8) is an anti-human TNFα antibody-glucocorticoid receptor agonist (GC) conjugate. Glucocorticoid receptor agonist-3 Ala-Ala-Mal can be used in the study of autoimmune and inflammatory diseases.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Glucocorticoid receptor agonist-3 Ala-Ala-Mal 構造式

CAS 番号 : 3014393-35-9

容量	価格（税別）	在庫状況	数量
1 mg	$430	在庫あり	Estimated Time of Arrival: December 31
5 mg	$1075	在庫あり	Estimated Time of Arrival: December 31
10 mg	$1720	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of Glucocorticoid receptor agonist-3 Ala-Ala-Mal:

Glucocorticoid receptor agonist-4 Ala-Ala-Mal お問い合わせ

TNF Receptor アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

TNFRSF1A/CD120a TNFRSF3/CD18 TNFRSF4 TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF7/CD27 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF10B/DR5/CD262 TNFRSF12A/TWEAK TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

Drug-Linker Conjugates for ADC アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents Dual payloads

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

体外実験

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

910.98

分子式

C₄₉H₅₅FN₄O₁₂

CAS 番号

3014393-35-9

Appearance

Solid

Color

White to off-white

SMILES

OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@H](C6=C(C(OCC7=CC(NC([C@H](C)NC([C@H](C)NC(CCN8C(C=CC8=O)=O)=O)=O)=O)=CC=C7)=CC=C6C)F)O2)C)=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (109.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0977 mL	5.4886 mL	10.9772 mL
5 mM	0.2195 mL	1.0977 mL	2.1954 mL
10 mM	0.1098 mL	0.5489 mL	1.0977 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.72%

Select Batch:

データシート (271 KB) SDS (252 KB)

COA (250 KB) HNMR (175 KB) RP-HPLC (229 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Grace CHAO, et al. Human tumor necrosis factor alpha antibody glucocorticoid conjugates. Patent WO2023220549A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0977 mL	5.4886 mL	10.9772 mL	27.4430 mL
	5 mM	0.2195 mL	1.0977 mL	2.1954 mL	5.4886 mL
	10 mM	0.1098 mL	0.5489 mL	1.0977 mL	2.7443 mL
	15 mM	0.0732 mL	0.3659 mL	0.7318 mL	1.8295 mL
	20 mM	0.0549 mL	0.2744 mL	0.5489 mL	1.3721 mL
	25 mM	0.0439 mL	0.2195 mL	0.4391 mL	1.0977 mL
	30 mM	0.0366 mL	0.1830 mL	0.3659 mL	0.9148 mL
	40 mM	0.0274 mL	0.1372 mL	0.2744 mL	0.6861 mL
	50 mM	0.0220 mL	0.1098 mL	0.2195 mL	0.5489 mL
	60 mM	0.0183 mL	0.0915 mL	0.1830 mL	0.4574 mL
	80 mM	0.0137 mL	0.0686 mL	0.1372 mL	0.3430 mL
	100 mM	0.0110 mL	0.0549 mL	0.1098 mL	0.2744 mL