Glucocorticoid receptor agonist-3 Ala-Ala-Mal
Based on 1 Customer Validation
Glucocorticoid receptor agonist-3 Ala-Ala-Mal (Compound Preparation 8) is an anti-human TNFα antibody-glucocorticoid receptor agonist (GC) conjugate. Glucocorticoid receptor agonist-3 Ala-Ala-Mal can be used in the study of autoimmune and inflammatory diseases.
For research use only. We do not sell to patients.
- Purity: 99.70%
- CAS No.: 3014393-35-9
- Formula: C49H55FN4O12
- Molecular Weight:910.98
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3014393-35-9
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Appearance Solid
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Molecular Weight 910.98
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Formula C49H55FN4O12
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Color White to off-white
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SMILES
OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@H](C6=C(C(OCC7=CC(NC([C@H](C)NC([C@H](C)NC(CCN8C(C=CC8=O)=O)=O)=O)=O)=CC=C7)=CC=C6C)F)O2)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (109.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0977 mL | 5.4886 mL | 10.9772 mL | 27.4430 mL |
| 5 mM | 0.2195 mL | 1.0977 mL | 2.1954 mL | 5.4886 mL | |
| 10 mM | 0.1098 mL | 0.5489 mL | 1.0977 mL | 2.7443 mL | |
| 15 mM | 0.0732 mL | 0.3659 mL | 0.7318 mL | 1.8295 mL | |
| 20 mM | 0.0549 mL | 0.2744 mL | 0.5489 mL | 1.3721 mL | |
| 25 mM | 0.0439 mL | 0.2195 mL | 0.4391 mL | 1.0977 mL | |
| 30 mM | 0.0366 mL | 0.1830 mL | 0.3659 mL | 0.9148 mL | |
| 40 mM | 0.0274 mL | 0.1372 mL | 0.2744 mL | 0.6861 mL | |
| 50 mM | 0.0220 mL | 0.1098 mL | 0.2195 mL | 0.5489 mL | |
| 60 mM | 0.0183 mL | 0.0915 mL | 0.1830 mL | 0.4574 mL | |
| 80 mM | 0.0137 mL | 0.0686 mL | 0.1372 mL | 0.3430 mL | |
| 100 mM | 0.0110 mL | 0.0549 mL | 0.1098 mL | 0.2744 mL |
Glucocorticoid receptor agonist-3 Ala-Ala-Mal Related Classifications
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