Fmoc-Ala-Ala-Asn(Trt)-OH
Based on 1 Customer Validation
Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 99.80%
- CAS No.: 1951424-92-2
- Formula: C44H42N4O7
- Molecular Weight:738.83
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Storage:
Stored under nitrogen, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1951424-92-2
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Appearance Solid
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Molecular Weight 738.83
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Formula C44H42N4O7
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Color White to off-white
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SMILES
OC([C@@H](NC([C@@H](NC([C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C)=O)C)=O)CC(NC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Stored under nitrogen, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (169.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.3535 mL | 6.7675 mL | 13.5349 mL | 33.8373 mL |
| 5 mM | 0.2707 mL | 1.3535 mL | 2.7070 mL | 6.7675 mL | |
| 10 mM | 0.1353 mL | 0.6767 mL | 1.3535 mL | 3.3837 mL | |
| 15 mM | 0.0902 mL | 0.4512 mL | 0.9023 mL | 2.2558 mL | |
| 20 mM | 0.0677 mL | 0.3384 mL | 0.6767 mL | 1.6919 mL | |
| 25 mM | 0.0541 mL | 0.2707 mL | 0.5414 mL | 1.3535 mL | |
| 30 mM | 0.0451 mL | 0.2256 mL | 0.4512 mL | 1.1279 mL | |
| 40 mM | 0.0338 mL | 0.1692 mL | 0.3384 mL | 0.8459 mL | |
| 50 mM | 0.0271 mL | 0.1353 mL | 0.2707 mL | 0.6767 mL | |
| 60 mM | 0.0226 mL | 0.1128 mL | 0.2256 mL | 0.5640 mL | |
| 80 mM | 0.0169 mL | 0.0846 mL | 0.1692 mL | 0.4230 mL | |
| 100 mM | 0.0135 mL | 0.0677 mL | 0.1353 mL | 0.3384 mL |
Fmoc-Ala-Ala-Asn(Trt)-OH Related Classifications
HY-130933 Related Classifications
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