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Cat. No.: HY-129407

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AAF-CMK TFA

(Synonyms: Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase inhibitor II)

AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.

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CAS No.: 184901-82-4
Formule: C₁₈H₂₃ClF₃N₃O₅
Masse moléculaire:453.84

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

AAF-CMK TFA Chemical Structure

CAS No.: 184901-82-4

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Description

Chemical Information

CAS No. 184901-82-4
Masse moléculaire 453.84
Formule C₁₈H₂₃ClF₃N₃O₅
SMILES

C[C@@H](C(N)=O)N(C([C@H](C)N)=O)[C@@H](CC1=CC=CC=C1)C(CCl)=O.O=C(O)C(F)(F)F
Synonyms

Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase inhibitor II
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Macpherson, et al. Supramolecular structure of tripeptidyl peptidase II from human erythrocytes as studied by electron microscopy, and its correlation to enzyme activity. Biochem. J. 248(1), 259-263 (1987).

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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AAF-CMK TFA

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AAF-CMK TFA Related Classifications

HY-129407 Related Classifications