Azido-PEG5-Ala-Ala-Asn-PAB
Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- CAS No.: 2055048-54-7
- Formula: C30H47N7O12
- Molecular Weight:697.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2055048-54-7
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Molecular Weight 697.73
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Formula C30H47N7O12
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SMILES
O=C(O)C[C@@H](C(NC1=CC=C(CO)C=C1)=O)NC([C@H](C)NC([C@H](C)NC(CCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)