2055048-54-7
Chemical Structure
Azido-PEG5-Ala-Ala-Asn-PAB
- CAS No.: 2055048-54-7
- Formula:C30H47N7O12
- Molecular Weight:697.73
IUPAC Name: (20S,23S,26S)-1-azido-26-((4-(hydroxymethyl)phenyl)carbamoyl)-20,23-dimethyl-18,21,24-trioxo-3,6,9,12,15-pentaoxa-19,22,25-triazaoctacosan-28-oic acid
InChIKey: FYXWRYWMFYMQKH-HWBMXIPRSA-N
SMILES: O=C(O)C[C@@H](C(NC1=CC=C(CO)C=C1)=O)NC([C@H](C)NC([C@H](C)NC(CCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O)=O
Biological Activity: Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azido-PEG5-Ala-Ala-Asn-PAB | Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-Ala-Ala-Asn-PAB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords
