MC-Ala-Ala-PAB
Based on 1 Customer Validation
MC-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 97.32%
- CAS No.: 1949793-44-5
- Formula: C23H30N4O6
- Molecular Weight:458.51
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1949793-44-5
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Appearance Solid
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Molecular Weight 458.51
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Formula C23H30N4O6
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Color Light yellow to yellow
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SMILES
OCC(C=C1)=CC=C1NC([C@H](C)NC([C@H](C)NC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 20.59 mg/mL (44.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.1810 mL | 10.9049 mL | 21.8098 mL | 54.5244 mL |
| 5 mM | 0.4362 mL | 2.1810 mL | 4.3620 mL | 10.9049 mL | |
| 10 mM | 0.2181 mL | 1.0905 mL | 2.1810 mL | 5.4524 mL | |
| 15 mM | 0.1454 mL | 0.7270 mL | 1.4540 mL | 3.6350 mL | |
| 20 mM | 0.1090 mL | 0.5452 mL | 1.0905 mL | 2.7262 mL | |
| 25 mM | 0.0872 mL | 0.4362 mL | 0.8724 mL | 2.1810 mL | |
| 30 mM | 0.0727 mL | 0.3635 mL | 0.7270 mL | 1.8175 mL | |
| 40 mM | 0.0545 mL | 0.2726 mL | 0.5452 mL | 1.3631 mL |
MC-Ala-Ala-PAB Related Classifications
HY-148464 Related Classifications
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