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Results for "

Eupatorium chinense</i> L,

" in MedChemExpress (MCE) Product Catalog:

67

Inhibitors & Agonists

1

Peptides

68

Natural
Products

Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-125665
    Pheophorbide A

    		Apoptosis Cardiovascular Disease Cancer
    Pheophorbide A is an intermediate product in the chlorophyll degradation pathway. Pheophorbide A can be used as a photosensitizer. Pheophorbide A is a lymphatic vascular activator. Pheophorbide A has antitumor activity. Pheophorbide A can be used for human lymphatic vascular insufficiencies research .
    Pheophorbide A
  • HY-N0246
    Saikosaponin A
    5 Publications Verification

    		 LXR Bacterial Inflammation/Immunology Cancer
    Saikosaponin A is the main active ingredient in Bupleurum chinense, which can regulate lipid metabolism and promote cholesterol efflux in early atherosclerosis. In addition, Saikosaponin A may also serve as a potential peroxisome proliferator-activated receptor γ (PPAR-γ) agonist, significantly promoting the expression of PPAR-γ. Saikosaponin A can be used in the study of hyperlipidemic pancreatitis .
    Saikosaponin A
  • HY-N0753
    Eupalinolide B

    		Apoptosis Autophagy Reactive Oxygen Species (ROS) GSK-3 β-catenin MAP3K JNK NF-κB p38 MAPK Neurological Disease Inflammation/Immunology Cancer
    Eupalinolide B is a germ sesquiterpene. Eupalinolide B can be isolated from Eupatorium lindleyanum. Eupalinolide B induces Apoptosis, elevates ROS, promotes Autophagy. regulates GSK-3β/β-catenin, targets UBE2D3 and TAK1, activates ROS-ER-JNK, inhibits NF-κB and MAPKs. Eupalinolide B has anticancer activity against pancreatic cancer and liver cancer. Eupalinolide B relieves rheumatoid arthritis, acute lung injury, periodontitis, depression .
    Eupalinolide B
  • HY-N2572
    Eupafolin

    Nepetin; 6-Methoxyluteolin

    		 Interleukin Related Neurological Disease Inflammation/Immunology Cancer
    Eupafolin (Nepetin) (6-Methoxyluteolin) is a natural flavonoid isolated from Eupatorium ballotaefolium HBK with potent anti-inflammatory activities. Eupafolin inhibits IL-6, IL-8 and MCP-1 secretion with IC50 values of 4.43 μM, 3.42 μM and 4.17 μM, respectively in ARPE-19 cells .
    Eupafolin
  • HY-N2392
    Kukoamine A
    1 Publications Verification

    		 Parasite Lipoxygenase Opioid Receptor Apoptosis Autophagy Reactive Oxygen Species (ROS) Interleukin Related TNF Receptor PGE synthase COX Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Kukoamine A, a spermine alkaloid, is an orally active and brain-penetrant component found in the root barks of Lycium chinense (L. chinense) Miller. Kukoamine A inhibits purified Crithidia fasciculata trypanothione reductase and soybean lipoxygenase, activates μ-opioid receptor. Kukoamine A can inhibt cancer cell proliferation, migration and invasion, cause G0/G1 phase cell cycle arrest and induce apoptosis. Kukoamine A exerts neuroprotective effect and can induce autophagy . Kukoamine A inhibits LPS (HY-D1056)-induced NO, ROS, PGE2, TNF-α, IL-1β, IL-6 production and COX-2 activity. Kukoamine A reverses palmitic acid-induced insulin resistance, lipid accumulation, and oxidative stress via downregulation of Srebp-1c. Kukoamine A can be used for the research of cancer, infection, inflammation, metabolic and neurological disease, such as glioblastoma and Parkinson's disease .
    Kukoamine A
  • HY-N0208
    Kaempferol-3-O-glucorhamnoside

    		p38 MAPK NF-κB Inflammation/Immunology
    Kaempferol-3-O-glucorhamnoside, a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPK and NF-κB pathways in vitro and in vivo .
    Kaempferol-3-O-glucorhamnoside
  • HY-N4314
    Scutellarein tetramethyl ether
    4 Publications Verification

    4',5,6,7-Tetramethoxyflavone

    		 Bacterial COX NO Synthase NF-κB Infection Inflammation/Immunology Cancer
    Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive compound extracted from Eupatorium odoratum. Scutellarein tetramethyl ether exhibits anti-inflammatory, antibacterial, pro-coagulant, and anti-tumor activities. Scutellarein tetramethyl ether exerts its anti-inflammatory effects by modulating the NF-κB pathway and regulates bacterial resistance through the inhibition of efflux pumps. Additionally, Scutellarein tetramethyl ether accelerates coagulation time via the endogenous coagulation pathway. Studies have shown that Scutellarein tetramethyl ether can effectively inhibit the growth of the liver cancer cell line HepG2 (IC50= 20.08 μg/mL) .
    Scutellarein tetramethyl ether
  • HY-N2138
    Buddlejasaponin IVb

    		Others Inflammation/Immunology
    Buddlejasaponin IVb (Compound 2), a triterpene saponin isolated from Clinopodium chinense (Benth.) O. Kuntze, Compound 2 has hemostasis efficacy, shortens thrombin time (TT) by 20.6 % .
    Buddlejasaponin IVb
  • HY-N10886
    Eupatolitin

    Eupatoletin

    		 Others Others
    Eupatoletin is a flavonol compound isolated from Eupatorium ligustrinum D.C. .
    Eupatolitin
  • HY-N5117
    Kaempferol 3-sophoroside-7-glucoside

    		Others Metabolic Disease
    Kaempferol 3-sophoroside-7-glucoside is a bioactive component in roasted Lycium chinense leaves with anti-obesity activity .
    Kaempferol 3-sophoroside-7-glucoside
  • HY-N4237
    Saikogenin D
    1 Publications Verification

    		 Prostaglandin Receptor Potassium Channel Inflammation/Immunology
    Saikogenin D is isolated from?Bupleurum chinense, has anti-inflammatory effects. Saikogenin D activates epoxygenases that converts arachidonic acid to epoxyeicosanoids and dihydroxyeicosatrienoic acids, and the metabolites secondarily inhibit prostaglandin E2 (PGE2) production. Saikogenin D results in an elevation of [Ca 2+]i due to Ca 2+ release from intracellular stores .
    Saikogenin D
  • HY-N2240
    Eupalinolide K

    		STAT Cancer
    Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) .
    Eupalinolide K
  • HY-N10925
    9-Hydroxythymol

    		Others Others
    9-Hydroxythymol is a thymol derivative. 9-Hydroxythymol can be isolated from Eupatorium fortunei .
    9-Hydroxythymol
  • HY-N10073
    Eupahualin C

    		Others Cancer
    Eupahualin C is a sesquiterpene lactone that can be isolated from Eupatorium hualienense. Eupahualin C shows cytotoxicity to K562 and U2OS cancer cells .
    Eupahualin C
  • HY-N7903
    Complanatoside B

    		Others Inflammation/Immunology
    Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects .
    Complanatoside B
  • HY-N6955
    Eupalinilide B

    		Others Cancer
    Eupalinilide B is a guaiane type sesquiterpene lactone that can be found in Eupatorium lindleyanum. Eupalinilide B shows potent cytotoxicity against P-388 and A-549 tumor cell lines .
    Eupalinilide B
  • HY-N16513
    Muurol-4-ene-3,8-dione

    		Others Metabolic Disease
    Muurol-4-ene-3,8-dione (Compound 2), a sesquiterpene, is one of the main hepatotoxic components in Eupatorium adenophorum. Muurol-4-ene-3,8-dione has an inhibitory effect on the growth of both the normal human hepatocyte cell L02 and the human hepatocellular carcinoma cell HepG2 with IC50 values of 87.52 and 104.48 μM .
    Muurol-4-ene-3,8-dione
  • HY-125545
    Cynanester A

    		Others Others
    Cynanester A is a active product that can be isolated from Cynanchum chinense R. Br. .
    Cynanester A
  • HY-N3838
    Epitulipinolide diepoxide

    		Others Cancer
    Epitulipinolide diepoxide (compound 9) is a natural compound isolated from the herbs of Liriodendron chinense (Hemsl.) Sarg. Epitulipinolide diepoxide displays cytoxicity in A375 cells, with the IC50 of 52.03 μM .
    Epitulipinolide diepoxide
  • HY-N9402
    Prosaikogenin A

    		Others Cardiovascular Disease
    Prosaikogenin A is a triterpene saponin isolated from Clinopodium chinense. Prosaikogenin A has significant promoting effects on platelet aggregation with an EC50 value of 12.2 μM .
    Prosaikogenin A
  • HY-N9172
    Eupaglehnin C

    		Others Cancer
    Eupaglehnin C is a germacrane-type sesquiterpenoi. Eupaglehnin C can be isolated from the MeOH extract of Eupatorium glehni (Compositae). Eupaglehnin C has cytotoxic activity against HeLa-S3 cancer cell lines .
    Eupaglehnin C
  • HY-N2802
    Euptox A

    9-Oxo-10,11-dehydroageraphorone

    		 Apoptosis Caspase Parasite Infection Cancer
    Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells .
    Euptox A
  • HY-N16623
    Erythro-guaiacylglycerol β-threo-syringylglycerol ether

    		Others Others
    Erythro-guaiacylglycerol β-threo-syringylglycerol ether (Compound 17) is a phenylpropanoid. Erythro-guaiacylglycerol β-threo-syringylglycerol ether can be isolated from the whole plants of T. chinense. Erythro-guaiacylglycerol β-threo-syringylglycerol ether exhibits moderate antioxidant activity .
    Erythro-guaiacylglycerol β-threo-syringylglycerol ether
  • HY-N0246R
    Saikosaponin A (Standard)

    		Reference Standards LXR Bacterial Metabolic Disease Inflammation/Immunology
    Saikosaponin A (Standard) is the analytical standard of Saikosaponin A. This product is intended for research and analytical applications. Saikosaponin A is the main active ingredient in Bupleurum chinense, which can regulate lipid metabolism and promote cholesterol efflux in early atherosclerosis. In addition, Saikosaponin A may also act as a potential peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist, significantly promoting the expression of PPAR-γ. Saikosaponin A can be used in the study of hyperlipidemic pancreatitis .
    Saikosaponin A (Standard)
  • HY-107257
    Eupalinilide C

    		Others Others
    Eupalinilide C is a nature product that could be isolated from Eupatorium lindleyanum .
    Eupalinilide C
  • HY-107256
    Eupalinilide D

    		Others Others
    Eupalinilide D is a natural product that can be isolated from Eupatorium lindleyanum .
    Eupalinilide D
  • HY-N12499
    Eupalitin

    		Others Others
    Eupalitin, flavonol, is an active natural product. Eupalitin can be isolated from Eupatorium ligustrinum D.C .
    Eupalitin
  • HY-N1751
    (Rac)-Phytene-1,2-diol

    		Others Infection
    7,11,15-Trimethyl-3-methylidenehexadecane-1,2-diol is a terpenoid that can be isolated from Eupatorium fortunei. 7,11,15-Trimethyl-3-methylidenehexadecane-1,2-diol is used in dropsy, chill, and fever research .
    (Rac)-Phytene-1,2-diol
  • HY-N8394
    Eupatolide

    		Others Cancer
    Eupatolide is an antitumor agent that can be isolated from Eupatorium formosanum. Eupatolide has cytotoxic activity and inhibits human epidermoid carcinoma of larynx cell growth in vitro .
    Eupatolide
  • HY-N3084
    Phellochin

    		Others Others
    Phellochin is a Triterpenoids product that can be isolated from the barks of Phellodendron chinense .
    Phellochin
  • HY-N2956
    Bourjotinolone A

    		Others Others
    Bourjotinolone A is a Triterpenoids product that can be isolated from the barks of Phellodendron chinense Schneid. .
    Bourjotinolone A
  • HY-124916
    Lycopsamine

    		Others Cancer
    Lycopsamine, a pyrrolizidine alkaloid, is a potential antitumor agent isolated from Eupatorium maculatum L. .
    Lycopsamine
  • HY-N9486
    2-Hydroxyeupatolide

    		Others Others
    2-Hydroxyeupatolide is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium lindleyanum .
    2-Hydroxyeupatolide
  • HY-N12590
    6′′-O-Acetylsaikosaponin b2

    		Others Others
    6′′-O-Acetylsaikosaponin b2 (compound 11) is a natural saikosaponin found in Bupleurum chinense .
    6′′-O-Acetylsaikosaponin b2
  • HY-N2648
    5,5'-Dimethoxylariciresinol

    		Others Others
    5,5'-Dimethoxylariciresinol is a Lignans product that can be isolated from the barks of Phellodendron chinense Schneid. .
    5,5'-Dimethoxylariciresinol
  • HY-N8828
    6''-O-Acetylsaikosaponin D

    		Others Others
    6''-O-Acetylsaikosaponin D is a Triterpenoids product that can be isolated from the herbs of Bupleurum chinense DC. .
    6''-O-Acetylsaikosaponin D
  • HY-N8293
    Eupalinolide I

    		Others Cancer
    Eupalinolide I inhibits the viability of breast cancer cells. Eupalinolide I can be isolated from Eupatorium lindleyanum .
    Eupalinolide I
  • HY-N7613
    6''-O-Acetylsaikosaponin A

    		Others Others
    6''-O-Acetylsaikosaponin A, an acetyl saikosaponin isolated from the roots of Bupleurum chinense, shows some osteoclast-inhibiting activities .
    6''-O-Acetylsaikosaponin A
  • HY-124916R
    Lycopsamine (Standard)

    		Reference Standards Others Cancer
    Lycopsamine (Standard) is the analytical standard of Lycopsamine. This product is intended for research and analytical applications. Lycopsamine, a pyrrolizidine alkaloid, is a potential antitumor agent isolated from Eupatorium maculatum L. .
    Lycopsamine (Standard)
  • HY-N2572R
    Eupafolin (Standard)

    Nepetin (Standard); 6-Methoxyluteolin (Standard)

    		 Reference Standards Interleukin Related Inflammation/Immunology
    Eupafolin (Standard) is the analytical standard of Eupafolin. This product is intended for research and analytical applications. Eupafolin (6-Methoxyluteolin) is a natural flavonoid isolated from Eupatorium ballotaefolium HBK with potent anti-inflammatory activities. Eupafolin inhibits IL-6, IL-8 and MCP-1 secretion with IC50 values of 4.43 μM, 3.42 μM and 4.17 μM, respectively in ARPE-19 cells .
    Eupafolin (Standard)
  • HY-N11507
    Tibesaikosaponin V

    TKV

    		 PPAR Metabolic Disease
    Tibesaikosaponin V (TKV) is a triterpene diglycoside, which can be isolated from the methanol extract of the roots of Bupleurum chinense DC.. Tibesaikosaponin V inhibits lipid accumulation and triacylglycerol content occurred without cytotoxicity to adipocytes. Tibesaikosaponin V suppresses the mRNA expression of nuclear transcription factors, such as peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα). Tibesaikosaponin V inhibits 3T3-L1 preadipocyte differentiation. Tibesaikosaponin V can be used fro research of obesity and its associated metabolic disorders .
    Tibesaikosaponin V
  • HY-N4314R
    Scutellarein tetramethyl ether (Standard)

    4',5,6,7-Tetramethoxyflavone (Standard)

    		 Reference Standards Bacterial COX NO Synthase NF-κB Infection Inflammation/Immunology Cancer
    Scutellarein tetramethyl ether (Standard) is the analytical standard of Scutellarein tetramethyl ether. This product is intended for research and analytical applications. Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive compound extracted from Eupatorium odoratum. Scutellarein tetramethyl ether exhibits anti-inflammatory, antibacterial, pro-coagulant, and anti-tumor activities. Scutellarein tetramethyl ether exerts its anti-inflammatory effects by modulating the NF-κB pathway and regulates bacterial resistance through the inhibition of efflux pumps. Additionally, Scutellarein tetramethyl ether accelerates coagulation time via the endogenous coagulation pathway. Studies have shown that Scutellarein tetramethyl ether can effectively inhibit the growth of the liver cancer cell line HepG2 (IC50= 20.08 μg/mL) .
    Scutellarein tetramethyl ether (Standard)
  • HY-N17497
    6′-O-Galloylsalicin

    		Others Others
    6′-O-Galloylsalicin is a phenolic glycoside found in the dried leaves of Alangium chinense .
    6′-O-Galloylsalicin
  • HY-N9260
    4E-Deacetylchromolaenide 4'-O-acetate

    		Others Inflammation/Immunology
    4E-Deacetylchromolaenide 4'-O-acetate (Compound 11) is a sesquiterpenoid that can be isolated fromEupatorium chinense L. .
    4E-Deacetylchromolaenide 4'-O-acetate
  • HY-N18188
    6'-O-trans-Caffeoylallicin

    		Others Others
    6'-O-trans-Caffeoylallicin (compound 1) is a phenolic glycoside found in the leaves of Alangium chinense .
    6'-O-trans-Caffeoylallicin
  • HY-N17449
    4’,6’-Di-O-galloylsalicin

    		Drug Derivative Others
    4’,6’-Di-O-galloylsalicin is a phenolic glycoside that can be found in the dried leaves of Alangium chinense .
    4’,6’-Di-O-galloylsalicin
  • HY-N9162
    2α-Hydroxyeupatolide 8-O-angelate

    		Others Others
    2α-Hydroxyeupatolide 8-O-angelate is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium chinense var. tozanense. .
    2α-Hydroxyeupatolide 8-O-angelate
  • HY-N1810
    Ditigloylteloidine

    3α,6β-Ditigloyloxytropan-7β-ol

    		 Others Others
    Ditigloylteloidine (3α,6β-Ditigloyloxytropan-7β-ol) is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium chinense var. tozanense. .
    Ditigloylteloidine
  • HY-N17408
    (E)-2-(2-Hydroxy-4-methylpheny1)-prop-l-en-1-yl acetate

    		Others Others
    (E)-2-(2-Hydroxy-4-methylphenyl)-prop-1-en-1-yl acetate is a natural product. (E)-2-(2-Hydroxy-4-methylphenyl)-prop-1-en-1-yl acetate can be isolated in the aerial parts of Eupatorium fortunei .
    (E)-2-(2-Hydroxy-4-methylpheny1)-prop-l-en-1-yl acetate
  • HY-N17409
    Eupatobenzofuran

    		Drug Derivative Others
    Eupatobenzofuran is a dihydrobenzofuran derivative that can be found in the aerial part of Eupatorium cannabinum subsp. asiaticum. Eupatobenzofuran inhibits fMLP/CB-induced elastase release by human neutrophils with an IC50 value of 11.3 μM .
    Eupatobenzofuran

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