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Cat. No.: HY-N17409

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Eupatobenzofuran

Eupatobenzofuran is a dihydrobenzofuran derivative that can be found in the aerial part of Eupatorium cannabinum subsp. asiaticum. Eupatobenzofuran inhibits fMLP/CB-induced elastase release by human neutrophils with an IC₅₀ value of 11.3 μM.

For research use only. We do not sell to patients.

CAS No.: 1275622-19-9
Formula: C₁₅H₁₈O₄
Molecular Weight:262.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Eupatobenzofuran Chemical Structure

CAS No.: 1275622-19-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
Neutrophil	IC₅₀	11.3 μM Compound: 3, Eupatobenzofuran	Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/cytochalasin B-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate after 5 mins Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/cytochalasin B-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate after 5 mins	[PMID: 21391659]

In Vitro

Eupatobenzofuran (5 min pre-incubation before fMLP/CB activation) inhibits fMLP/CB-induced elastase release in human neutrophils with an IC₅₀ of 11.3 μM and inhibits superoxide anion generation by 37.1 % at 10 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1275622-19-9
Molecular Weight 262.30
Formula C₁₅H₁₈O₄
SMILES

C[C@]1(C2=CC=C(C)C=C2O[C@H]1OC(/C(C)=C\C)=O)O
Structure Classification
- Phenylpropanoids
- Simple Phenylpropanols
Initial Source
- Plants
- Compositae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chen JJ, et al. Thymol, benzofuranoid, and phenylpropanoid derivatives: anti-inflammatory constituents from Eupatorium cannabinum. J Nat Prod. 2011;74(5):1021-1027. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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