Eupatobenzofuran
Eupatobenzofuran is a dihydrobenzofuran derivative that can be found in the aerial part of Eupatorium cannabinum subsp. asiaticum. Eupatobenzofuran inhibits fMLP/CB-induced elastase release by human neutrophils with an IC50 value of 11.3 μM.
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- CAS No.: 1275622-19-9
- 화학식: C15H18O4
- 분자량:262.30
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Neutrophil | IC50 |
11.3 μM
Compound: 3, Eupatobenzofuran
|
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/cytochalasin B-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate after 5 mins
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/cytochalasin B-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate after 5 mins
|
[PMID: 21391659] |
In Vitro
Eupatobenzofuran (5 min pre-incubation before fMLP/CB activation) inhibits fMLP/CB-induced elastase release in human neutrophils with an IC50 of 11.3 μM and inhibits superoxide anion generation by 37.1 % at 10 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1275622-19-9
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분자량 262.30
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화학식 C15H18O4
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SMILES
C[C@]1(C2=CC=C(C)C=C2O[C@H]1OC(/C(C)=C\C)=O)O
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Structure Classification
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)