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Cat. No.: HY-N12590

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6′′-O-Acetylsaikosaponin b2

6′′-O-Acetylsaikosaponin b2 (compound 11) is a natural saikosaponin found in Bupleurum chinense.

For research use only. We do not sell to patients.

CAS No.: 104121-82-6
Formula: C₄₄H₇₀O₁₄
Molecular Weight:823.02

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

6′′-O-Acetylsaikosaponin b2 Chemical Structure

CAS No.: 104121-82-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

6′′-O-Acetylsaikosaponin b2 (compound 11) is a natural saikosaponin found in Bupleurum chinense^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	69.32 μM Compound: 10	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 26883148]
Bcap37	IC₅₀	>80 μM Compound: 10	Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay	[PMID: 26883148]
Hep 3B2	IC₅₀	>80 μM Compound: 10	Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay	[PMID: 26883148]
HepG2	IC₅₀	21.84 μM Compound: 10	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 26883148]
MCF7	IC₅₀	46.53 μM Compound: 10	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 26883148]

Chemical Information

CAS No. 104121-82-6
Molecular Weight 823.02
Formula C₄₄H₇₀O₁₄
SMILES

C[C@]12C(C=C[C@@]3([H])[C@]2(CC[C@]4([H])[C@@]3(CC[C@@H]([C@@]4(C)CO)O[C@H]5[C@@H]([C@H]([C@H]([C@H](O5)C)O)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)COC(C)=O)O)C)C)=C7[C@@]([C@@H](C1)O)(CCC(C)(C7)C)CO
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
- Plants
- Umbelliferae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jin-Qian Yu, et al. Osteoclast-inhibiting saikosaponin derivatives from Bupleurum chinense. Fitoterapia. 2013 Mar:85:101-8. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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