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  5. 6''-O-Acetylsaikosaponin A

6''-O-Acetylsaikosaponin A, an acetyl saikosaponin isolated from the roots of Bupleurum chinense, shows some osteoclast-inhibiting activities.

For research use only. We do not sell to patients.

6''-O-Acetylsaikosaponin A Chemical Structure

6''-O-Acetylsaikosaponin A Chemical Structure

CAS No. : 64340-46-1

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Based on 1 publication(s) in Google Scholar

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Description

6''-O-Acetylsaikosaponin A, an acetyl saikosaponin isolated from the roots of Bupleurum chinense, shows some osteoclast-inhibiting activities[1].

In Vitro

The major bioactive compounds isolated from R. bupleuri are saikosaponins, which have been proved to possess significant biological activities, including anti-hepatitis, anti-inflammatory, anti-tumor and immunoregulatory effects[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

823.02

Formula

C44H70O14

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]1(C[C@@H]2O)[C@]3(C=C[C@@]4([H])[C@]1(CC[C@]([C@@](C)5CO)([H])[C@@]4(CC[C@@H]5O[C@H](O[C@@H]6C)[C@@H]([C@H]([C@H]6O)O[C@@H]([C@@H]([C@H]7O)O)O[C@@H]([C@H]7O)COC(C)=O)O)C)C)[C@@](CC8(C)C)([H])[C@@]2(CC8)CO3

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (121.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2150 mL 6.0752 mL 12.1504 mL
5 mM 0.2430 mL 1.2150 mL 2.4301 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2150 mL 6.0752 mL 12.1504 mL 30.3759 mL
5 mM 0.2430 mL 1.2150 mL 2.4301 mL 6.0752 mL
10 mM 0.1215 mL 0.6075 mL 1.2150 mL 3.0376 mL
15 mM 0.0810 mL 0.4050 mL 0.8100 mL 2.0251 mL
20 mM 0.0608 mL 0.3038 mL 0.6075 mL 1.5188 mL
25 mM 0.0486 mL 0.2430 mL 0.4860 mL 1.2150 mL
30 mM 0.0405 mL 0.2025 mL 0.4050 mL 1.0125 mL
40 mM 0.0304 mL 0.1519 mL 0.3038 mL 0.7594 mL
50 mM 0.0243 mL 0.1215 mL 0.2430 mL 0.6075 mL
60 mM 0.0203 mL 0.1013 mL 0.2025 mL 0.5063 mL
80 mM 0.0152 mL 0.0759 mL 0.1519 mL 0.3797 mL
100 mM 0.0122 mL 0.0608 mL 0.1215 mL 0.3038 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
6''-O-Acetylsaikosaponin A
Cat. No.:
HY-N7613
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