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Results for "

Penicillium

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (10) Apoptosis (6) Autophagy (2) Bacterial (10) Bcl-2 Family (1) c-Met/HGFR (1) Calcium Channel (1) Caspase (1) Cholinesterase (ChE) (1) Cytochrome P450 (1) Endogenous Metabolite (8) ERK (1) Farnesyl Transferase (1) Fungal (10) HSV (1) Influenza Virus (1) Interleukin Related (1) Isotope-Labeled Compounds (1) Lipoxygenase (1) MEK (1) Microtubule/Tubulin (1) Na+/K+ ATPase (1) Neurokinin Receptor (1) Opioid Receptor (1) P-glycoprotein (1) Parasite (3) Potassium Channel (3) Reactive Oxygen Species (1) SOD (1) Tyrosinase (1)
By Research Areas:	Cancer (15) Cardiovascular Disease (1) Endocrinology (1) Infection (28) Inflammation/Immunology (2) Neurological Disease (5)

By Targets:

Antibiotic (10)

Apoptosis (6)

Autophagy (2)

Bacterial (10)

Bcl-2 Family (1)

c-Met/HGFR (1)

Calcium Channel (1)

Caspase (1)

Cholinesterase (ChE) (1)

Cytochrome P450 (1)

Endogenous Metabolite (8)

ERK (1)

Farnesyl Transferase (1)

Fungal (10)

HSV (1)

Influenza Virus (1)

Interleukin Related (1)

Isotope-Labeled Compounds (1)

Lipoxygenase (1)

MEK (1)

Microtubule/Tubulin (1)

Na+/K+ ATPase (1)

Neurokinin Receptor (1)

Opioid Receptor (1)

P-glycoprotein (1)

Parasite (3)

Potassium Channel (3)

Reactive Oxygen Species (1)

SOD (1)

Tyrosinase (1)

By Research Areas:

Cancer (15)

Cardiovascular Disease (1)

Endocrinology (1)

Infection (28)

Inflammation/Immunology (2)

Neurological Disease (5)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N12184

Peniciside

Others Others

Peniciside is a triterpenoid glycoside derived from the fungus Penicillium sp.169 .
HY-129591

Paraherquamide A

PNU-97333
Others Others

Paraherquamide A (PNU-97333) is a toxic metabolite that can be isolated from Penicillium paraherquei .
HY-126697

Eremofortin A

Endogenous Metabolite Others

Eremofortin A is a metabolism that can be isolated from a culture of Penicillium roqueforti .
HY-126484

Eremofortin B

Others Others

Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT) .
HY-116479

Citromycetin

Others Others

Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .
HY-N12266

12-Hydroxyalbrassitriol

Others Others

12-Hydroxyalbrassitriol is a drimane sesquiterpenoid that can be isolated from Penicillium sp .

Peniciside	Others	Others
Peniciside is a triterpenoid glycoside derived from the fungus Penicillium sp.169 .

Paraherquamide A PNU-97333	Others	Others
Paraherquamide A (PNU-97333) is a toxic metabolite that can be isolated from Penicillium paraherquei .

Eremofortin A	Endogenous Metabolite	Others
Eremofortin A is a metabolism that can be isolated from a culture of Penicillium roqueforti .

Eremofortin B	Others	Others
Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT) .

Citromycetin	Others	Others
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

12-Hydroxyalbrassitriol	Others	Others
12-Hydroxyalbrassitriol is a drimane sesquiterpenoid that can be isolated from Penicillium sp .

HY-129279

Andrastin A	Farnesyl Transferase	Cancer
Andrastin A meroterpenoid compound, is a farnesyltransferase inhibitor. Andrastin A inhibits the efflux of anticancer compounds from multidrug-resistant cancer cells. Andrastin A can be isolated from Penicillium species .

HY-N7480A

Quinolactacin A1	Cholinesterase (ChE)	Neurological Disease
Quinolactacin A1 is a potent acetylcholinesterase (AChE) inhibitor from solid state fermentation of Penicillium citrinum 90648. Quinolactacin A1 can be used for the research of Alzheimer disease .

HY-126604

Pyranonigrin A	Others	Infection
Pyranonigrin A is isolated and identified from Penicillium brocae MA-231. Pyranonigrin A shows potent activity against a broad spectrum of human-, aqua-, and plant-pathogens .

HY-129806

Rugulosin (+)-Rugulosin	Bacterial Fungal	Infection
Rugulosin is a crystalline colouring matter of Penicillium rugulosum Thom. Rugulosin shows markedly specific antibacterial activity and moderately antifungal activity .

HY-N8287

Oxaline	Microtubule/Tubulin	Cancer
Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase .

HY-N12337

Asperazine (+)-Asperazine	Others	Cancer
Asperazine (Compound 5) is an alkaloid derived from the fungus Penicillium oxalicum. Asperazine shows only moderate activity against HepG2 and CaSki cell lines (IC₅₀>50 μM) .

HY-122076

A-26771B	Antibiotic Bacterial Fungal	Infection
A-26771B is an antibiotic can be obtained from Penicillium turbatum. A-26771B exhibits moderate antimicrobial activity against Gram-positive bacteria, mycoplasma, and fungi. A-26771B also inhibits potassium-dependent ATPase in rat liver mitochondria .

HY-N6748

Roquefortine C	P-glycoprotein Cytochrome P450 Bacterial Endogenous Metabolite	Infection Cancer
Roquefortine C, a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins. Roquefortine C has bacteriostatic activities against Gram-positive bacteria .

HY-W099579

Kojic acid dipalmitate Kojic dipalmitate	Tyrosinase	Endocrinology
Kojic acid dipalmitate (Kojic dipalmitate) is a derivative of Kojic acid (HY-W050154), a fungal metabolite that can be produced by species of Aspergillus, Acetobacter and Penicillium. Kojic acid dipalmitate is a slow and reversible competitive inhibitor of tyrosinase. Kojic acid dipalmitate can be used for skin‐lightening agent research .

HY-N12165

1,3,5,6-Tetrahydroxy-8-methylxanthone	Others	Others
1,3,5,6-Tetrahydroxy-8-methylxanthone (compound 8) is a dimeric 1,4-benzoquinone derivative isolated from the marine-derived fungus Penicillium genus .

HY-118463

Benzomalvin A	Neurokinin Receptor	Neurological Disease
Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with K_i values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively .

HY-N10177

Peniterphenyl A	HSV	Infection
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits HSV-1/2 virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-P5591

PAF26

Fungal Infection

PAF26 is an antimicrobial peptide against phytopathogenic fungi Penicillium digitatum, Penicillium italicum and Botrytis cinerea .
HY-N10215

Canadensolide

Fungal Endogenous Metabolite Infection

Canadensolide is an antifungal metabolite of Penicillium canadense.
HY-N8548

Fellutanine A

Endogenous Metabolite Infection

Fellutanine A, a diketopiperazine alkaloid, is a fungal metabolite from cultures of Penicillium fellutanum .
HY-125298

Cycloaspeptide A

Parasite Infection

Cycloaspeptide A, isolated from the endophytic fungus Penicillium janczewskii, has antiparasitic activity .
HY-129208

Viridicatumtoxin

Antibiotic Fungal Infection

Viridicatumtoxin is a new mycotoxin extracted from Penicillium viridicatum with a LD₅₀ of 122.4 mg/kg in rats.

PAF26	Fungal	Infection
PAF26 is an antimicrobial peptide against phytopathogenic fungi Penicillium digitatum, Penicillium italicum and Botrytis cinerea .

Canadensolide	Fungal Endogenous Metabolite	Infection
Canadensolide is an antifungal metabolite of Penicillium canadense.

Fellutanine A	Endogenous Metabolite	Infection
Fellutanine A, a diketopiperazine alkaloid, is a fungal metabolite from cultures of Penicillium fellutanum .

Cycloaspeptide A	Parasite	Infection
Cycloaspeptide A, isolated from the endophytic fungus Penicillium janczewskii, has antiparasitic activity .

Viridicatumtoxin	Antibiotic Fungal	Infection
Viridicatumtoxin is a new mycotoxin extracted from Penicillium viridicatum with a LD₅₀ of 122.4 mg/kg in rats.

HY-120154

Palitantin (±)-Palitantin	Parasite Endogenous Metabolite	Infection
Palitantin ((±)-Palitantin), a metabolite of Penicillium frequentans on Leishmania brasiliensis, has antiprotozoal effect against Leishmania brasiliensis .

HY-N10220

Paraherquamide E	Endogenous Metabolite Parasite	Infection
Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects .

HY-125546

Erythromycin C

Antibiotic Infection

Erythromycin C is an antibiotic. Erythromycin C could be isolated from the fermentation process of the penicillium Streptomyces erythreus .
HY-123474

PF-1163B

Fungal Antibiotic Infection

PF-1163B is an antifungal antibiotic .

Erythromycin C	Antibiotic	Infection
Erythromycin C is an antibiotic. Erythromycin C could be isolated from the fermentation process of the penicillium Streptomyces erythreus .

PF-1163B	Fungal Antibiotic	Infection
PF-1163B is an antifungal antibiotic .

HY-E70111

Endo-1,5-α-arabinanase Endo-1,5-arabinanase	Others	Others
Endo-1,5-α-arabinanase (Endo-1,5-arabinanase) belongs to CAZy family 43 of the glycoside hydrolase (GH). Endo-1,5-α-arabinanase mainly shorts arabinooligosaccharides and arabinose from debranched arabinan .

HY-125060

Viridicatin	Antibiotic Endogenous Metabolite	Infection
Viridicatin is a fungal metabolite from Penicillium species. Viridicatin shows slight in vitro antibiotic activity against Mycobacterium tuberculosis .

HY-129384

Rubratoxin B

Others Cancer

Rubratoxin B is a hepatotoxic mycotoxin that can be found in Penicillium rubrum Stoll. Rubratoxin B shows antitumor activity .

Rubratoxin B	Others	Cancer
Rubratoxin B is a hepatotoxic mycotoxin that can be found in Penicillium rubrum Stoll. Rubratoxin B shows antitumor activity .

HY-122404

Xantocillin Xanthocillin X	MEK ERK Autophagy	Cancer
Xantocillin (Xanthocillin X) is a marine agent extracted from Penicillium commune, induces autophagy through inhibition of the MEK/ERK pathway .

HY-124301

Penicolinate A	Bacterial	Infection
Penicolinate A is a picolinic acid derivative. Penicolinate A is isolated from endophytic Penicillium sp. BCC16054. Penicolinate A exhibits antimalarial and antitubercular activities .

HY-N10442

Herqueilenone A

Others Others

Herqueilenone A is a benzoquinone-chromanon that can be found in the Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729[1].

Herqueilenone A	Others	Others
Herqueilenone A is a benzoquinone-chromanon that can be found in the Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729[1].

HY-126983

6',7'-Epoxybergamottin Epoxybergamottin	Others	Others
6',7'-Epoxybergamottin is a metabolism of Penicillium digitatum. 6',7'-Epoxybergamottin can be used in study the cytochrome P450 3A4 inhibitory activity .

HY-N8498

GKK1032B	Apoptosis	Cancer
GKK1032B is an alkaloid compound that can be found in endophytic fungus Penicillium sp. GKK1032B can induce the apoptosis of human osteosarcoma MG63 cells through caspase pathway activation .

HY-116474

Viridicatol	Fungal	Infection
Viridicatol, a quinolinone alkaloid, is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum. Viridicatol has strong antifungal activity against Staphylococcus aureus with MIC value of 15.6 μg/mL .

HY-75564

Cyclo(Ala-Gly)	Endogenous Metabolite	Cancer
Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC₅₀ values range from 9.5 to 18.1 μM .

HY-N6688

Verruculogen	Potassium Channel Bacterial Antibiotic	Infection
Verruculogen is a toxin produced mainly by Penicillium and Aspergillus spp. and causes severe tremors in affected animals. Verruculogen inhibits Ca ²⁺-activated K ⁺ channels. Verruculogen is an M phase inhibitor of the mammalian cell cycle .

HY-N6777

Penicillic acid 1 Publications Verification	Caspase Bacterial Apoptosis Antibiotic	Infection Cancer
Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro. Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 .

HY-N6744

Chaetoglobosin A	Apoptosis	Infection Cancer
Chaetoglobosin A, the active principle within the extract of Penicillium aquamarinium, is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration .

HY-P4107

Bilaid C	Opioid Receptor	Neurological Disease
Bilaid C, a tetrapeptide, can be isolated from the Australian estuarine isolate of Penicillium sp. MST-MF667. Bilaid C is also a potent and selective μ-Opioid Receptor (MOPr) agonist (K_i=210 nM, hMOPr) .

HY-N6779

Patulin 3 Publications Verification Terinin	Bacterial Apoptosis Autophagy Antibiotic	Infection
Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage .

HY-117517

NG-012	Others	Cancer
NG-012, potentiator of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542. NG-012 potentiates the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12) .

HY-N6797

Meleagrin	Bacterial c-Met/HGFR Antibiotic	Infection Cancer
Meleagrin is a roquefortine C-derived alkaloid produced by fungi of the genus Penicillium and has antimicrobial and anti-proliferative activities. Meleagrin is a class of FabI inhibitor. Meleagrin is a lead c-Met inhibitory entity useful for the control of c-Met-dependent metastatic and invasive breast malignancies .

HY-N6027

Cyclosporin C	Fungal Bacterial	Infection
Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. Cyclosporin C is active against isolates of B. cinerea, A. niger, and Alternaria, Mucor, and Penicillium species (MICs=0.1-5 μg/ml).

HY-N6776

Penitrem A	Potassium Channel	Neurological Disease Cancer
Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals .

HY-N6745

Citreoviridin	Na+/K+ ATPase Apoptosis	Infection Cardiovascular Disease
Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na ⁺/K ⁺-ATPase whereas in microsomes, both Na ⁺/K ⁺-ATPase and Mg ²⁺-ATPase activities are significantly stimulated in a dose-dependent manner . Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells .

HY-N6778

Paxilline 5 Publications Verification	Potassium Channel Calcium Channel	Neurological Disease
Paxilline is an indole alkaloid mycotoxin from Penicillium paxilli, acts as a potent BK channels inhibitor by an almost exclusively closed-channel block mechanism. Paxilline also inhibits the sarco/endoplasmic reticulum Ca ²⁺ ATPase (SERCA) with IC₅₀s between 5 μM and 50 μM for differing isoforms. Paxilline possesses significant anticonvulsant activity .

HY-N6779S

Patulin-13C7 Terinin-¹³C₇	Isotope-Labeled Compounds	Infection
Patulin- ¹³C₇ (Terinin- ¹³C₇) is the ¹³C labeled Patulin (HY-N6779) . Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, is suspected to be clastogenic, mutagenic, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage .

HY-116866

Sclerotiorin	Lipoxygenase Fungal	Infection Inflammation/Immunology
Sclerotiorin is a reversible and uncompetitive inhibitor against soybean lipoxygenase-1 (LOX-1) (IC₅₀: 4.2 μM). Sclerotiorin also shows antioxidant activity by scavenging free radical (ED₅₀: 0.12 μM), and nonenzymatic lipid peroxidation inhibition activity. Sclerotiorin has antifungal activity, and also inhibits platelet aggregation. Sclerotiorin can be purified from the fermented broth of Penicillium frequentans .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N12184

Peniciside	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Others
Peniciside is a triterpenoid glycoside derived from the fungus Penicillium sp.169 .

HY-126697

Eremofortin A	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Eremofortin A is a metabolism that can be isolated from a culture of Penicillium roqueforti .

HY-126484

Eremofortin B	Structural Classification Natural Products Microorganisms Source classification	Others
Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT) .

HY-116479

Citromycetin	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Marine natural products Other Diseases Phenols Polyphenols Disease Research Fields Marine microorganism	Others
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

HY-N12266

12-Hydroxyalbrassitriol	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	Others
12-Hydroxyalbrassitriol is a drimane sesquiterpenoid that can be isolated from Penicillium sp .