1. Alkaloid
  2. Penitrem A

Penitrem A 

Cat. No.: HY-N6776
Handling Instructions

Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals.

For research use only. We do not sell to patients.

Penitrem A Chemical Structure

Penitrem A Chemical Structure

CAS No. : 12627-35-9

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Description

Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals[1][2].

IC50 & Target

BK channel[1]

Molecular Weight

634.20

Formula

C₃₇H₄₄ClNO₆

CAS No.

12627-35-9

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Penitrem A
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