Viridicatumtoxin
Viridicatumtoxin is a new mycotoxin extracted from Penicillium viridicatum with a LD50 of 122.4 mg/kg in rats.
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- CAS No.: 39277-41-3
- 화학식: C30H31NO10
- 분자량:565.57
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:ICR mice, Sprague-Dawley rats and mature Wistar rats (4/5 weeks; 16-20 g/140-150 g)[2]
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Dosage:60-400 mg/kg
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Administration:i.p., p.o., s.c.
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Result:Orally with viridicatumtoxin had no signs of toxicity. As the dosage increasing (i.p. and p.o.), hepatocytes started to have pathological changes and deaths occurred in both mice and rats. Mice and rats which given the viridicatumtoxin by s.c. had no signs of toxicity and none died, but coagulation necrosis was present at the injection site.
Chemical Information
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CAS No. 39277-41-3
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분자량 565.57
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화학식 C30H31NO10
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SMILES
O=C(C(C([C@@]12O)=O)=C(O)C[C@@]1(O)[C@H](O)C(C3=C[C@]4(C5=C3C(C(O)C=C5OC)=C6O)C(C)=CCCC4(C)C)=C6C2=O)N
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Structure Classification
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Initial Source
Penicillium viridicatum Westling
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Hutchison RD, et al. Viridicatumtoxin, a new mycotoxin from Penicillium viridicatum Westling. Toxicol Appl Pharmacol. 1973;24(3):507-509. [Content Brief]
[2]. Bendele AM, Carlton WW, Nelson GE, Peterson RE, Grove MD. Viridicatumtoxin mycotoxicosis in mice and rats. Toxicol Lett. 1984;22(3):287-291. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)