Andrastin A
Andrastin A meroterpenoid compound, is a farnesyltransferase inhibitor. Andrastin A inhibits the efflux of anticancer compounds from multidrug-resistant cancer cells. Andrastin A can be isolated from Penicillium species.
For research use only. We do not sell to patients.
- CAS No.: 174232-42-9
- Formula: C28H38O7
- Molecular Weight:486.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 174232-42-9
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Molecular Weight 486.60
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Formula C28H38O7
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SMILES
CC1=C[C@@]2([C@](C)(CC[C@@]3(C(C)([C@H](CC[C@]32C=O)OC(C)=O)C)[H])[C@@](C(OC)=O)([C@@]1(C4=O)C)C(C4C)=O)[H]
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Structure Classification
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Initial Source
Penicillium sp. FO-3929
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Nielsen KF, et al. Andrastins A-D, Penicillium roqueforti Metabolites consistently produced in blue-mold-ripened cheese. J Agric Food Chem. 2005 Apr 20;53(8):2908-13. [Content Brief]
[2]. Rojas-Aedo JF, et al. The Biosynthetic Gene Cluster for Andrastin A in Penicillium roqueforti. Front Microbiol. 2017 May 5;8:813. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)