1. Apoptosis
  2. Apoptosis
  3. Chaetoglobosin A

Chaetoglobosin A 

Cat. No.: HY-N6744
Handling Instructions

Chaetoglobosin A, the active principle within the extract of Penicillium aquamarinium, is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration.

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Chaetoglobosin A Chemical Structure

Chaetoglobosin A Chemical Structure

CAS No. : 50335-03-0

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Description

Chaetoglobosin A, the active principle within the extract of Penicillium aquamarinium, is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration[1].

IC50 & Target

Filamentous actin[1]

Molecular Weight

528.64

Formula

C₃₂H₃₆N₂O₅

CAS No.

50335-03-0

SMILES

O=C(/C=C/C1=O)[[email protected]](O)/C(C)=C/[[email protected]@H](C)C/C=C/[[email protected]]2([H])[[email protected]]31C(N[[email protected]@H](CC4=CNC5=C4C=CC=C5)[[email protected]]3([H])[[email protected]](C)[[email protected]]6(C)[[email protected]@]2([H])O6)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Chaetoglobosin A
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