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Cat. No.: HY-N8287

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Oxaline

Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase.

For research use only. We do not sell to patients.

CAS No.: 55623-37-5
Formula: C₂₄H₂₅N₅O₄
Molecular Weight:447.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

Oxaline Chemical Structure

CAS No.: 55623-37-5

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Biological Activity

Description

Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase^[1]^[2].

Chemical Information

CAS No. 55623-37-5
Molecular Weight 447.49
Formula C₂₄H₂₅N₅O₄
SMILES

O=C1N[C@@]23N(OC)C4=C(C=CC=C4)[C@]2(C(C)(C)C=C)C=C(OC)C(N3/C1=C/C5=CN=CN5)=O
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
- Microorganisms
Penicillium oxalicum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nagel D W, et al. X-Ray structure of oxaline: a novel alkaloid from Penicillium oxalicum. Journal of the Chemical Society. Chemical Communications. 1974 (24): 1021-1022.

[2]. Koizumi Y, et al. Oxaline, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of tubulin polymerization. Biochim Biophys Acta. 2004 Jul 23;1693(1):47-55. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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