Sclerotiorin
Sclerotiorin is a reversible and uncompetitive inhibitor against soybean lipoxygenase-1 (LOX-1) (IC50: 4.2 μM). Sclerotiorin also shows antioxidant activity by scavenging free radical (ED50: 0.12 μM), and nonenzymatic lipid peroxidation inhibition activity. Sclerotiorin has antifungal activity, and also inhibits platelet aggregation. Sclerotiorin can be purified from the fermented broth of Penicillium frequentans.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 549-23-5
- 分子式: C21H23ClO5
- 分子量:390.86
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
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Help & FAQs
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ViridicatolQuinolone Alkaloid
生物活性
製品説明
体外実験
Sclerotiorin (10 μM) slows Aβ42 fibrillogenesis in vitro, detected with 6E10 antibody[2].
Sclerotiorin shows narrow spectrum activity against Gram positive bacteria, with MIC range of 128-1028 μg/mL[3].
Sclerotiorin inhibits cholesteryl ester transfer protein (CETP) activity in vitro (IC50: 19.4 μM)[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 549-23-5
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分子量 390.86
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分子式 C21H23ClO5
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SMILES
O=C1[C@](C)(OC(C)=O)C(C2=COC(/C=C/C(C)=C/[C@@H](C)CC)=CC2=C1Cl)=O
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Structure Classification
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Initial Source
Penicillium multicolor
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Sclerotiorin 関連分類
HY-116866 関連分類
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