2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. Benzomalvin A

Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively.

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Benzomalvin A Chemical Structure

Benzomalvin A Chemical Structure

CAS No. : 157047-96-6

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Description

Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively[1].

Molecular Weight

381.43

Formula

C24H19N3O2
CAS No.
SMILES

O=C1N2C(C(N(C(C3=C2C=CC=C3)=O)C)CC4=CC=CC=C4)=NC5=CC=CC=C51
Structure Classification
Initial Source

Penicillium sp
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Benzomalvin A Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Benzomalvin A157047-96-6Neurokinin ReceptorNK receptorTachykinin receptorneurokinin receptorPenicillium spsubstance Pguinea pigrathumanInhibitorinhibitorinhibit

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