Citreoviridin
Based on 1 Customer Validation
Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells.
For research use only. We do not sell to patients.
- Purity: 98.39%
- CAS No.: 25425-12-1
- Formula: C23H30O6
- Molecular Weight:402.48
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
1.5 μM
Compound: Citreoviridin
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Antiproliferative activity against human A549 cells assessed as reduction in cell proliferation incubated for 48 hrs by xCELLigence RTCA system analysis
Antiproliferative activity against human A549 cells assessed as reduction in cell proliferation incubated for 48 hrs by xCELLigence RTCA system analysis
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[PMID: 32942072] |
| CL1-0 | IC50 |
1.5 μM
Compound: Citreoviridin
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Antiproliferative activity against human CL1-0 cells assessed as reduction in cell proliferation incubated for 48 hrs by xCELLigence RTCA system analysis
Antiproliferative activity against human CL1-0 cells assessed as reduction in cell proliferation incubated for 48 hrs by xCELLigence RTCA system analysis
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[PMID: 32942072] |
Chemical Information
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CAS No. 25425-12-1
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Appearance Solid
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Molecular Weight 402.48
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Formula C23H30O6
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Color Light yellow to yellow
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SMILES
CC(/C=C/C=C/C=C/C(O1)=C(C(OC)=CC1=O)C)=C\[C@]2([C@H](O)[C@]([C@H](O2)C)(O)C)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
Methanol : 10 mg/mL (24.85 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (479 KB)
- English - EN (479 KB)
- Français - FR (479 KB)
- Deutsch - DE (479 KB)
- Norwegian - NO (479 KB)
- Español - ES (479 KB)
- Swedish - SV (479 KB)
- Italian - IT (479 KB)
- Korean - KR (479 KB)
- Portuguese - PT (479 KB)
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Handling Instructions (2659 KB)
References
[1]. Datta SC, et al. Effect of citreoviridin, a mycotoxin from Penicillium citreoviride, on kinetic constants of acetylcholinesterase and ATPase in synaptosomes and microsomes from rat brain. Toxicon. 1981;19(4):555-62. [Content Brief]
[2]. Hou H, et al. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells. Environ Toxicol Pharmacol. 2014 Mar;37(2):828-36. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Methanol | 1 mM | 2.4846 mL | 12.4230 mL | 24.8460 mL | 62.1149 mL |
| 5 mM | 0.4969 mL | 2.4846 mL | 4.9692 mL | 12.4230 mL | |
| 10 mM | 0.2485 mL | 1.2423 mL | 2.4846 mL | 6.2115 mL | |
| 15 mM | 0.1656 mL | 0.8282 mL | 1.6564 mL | 4.1410 mL | |
| 20 mM | 0.1242 mL | 0.6211 mL | 1.2423 mL | 3.1057 mL |
Citreoviridin Related Classifications
HY-N6745 Related Classifications
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