1. Membrane Transporter/Ion Channel Apoptosis
  2. Na+/K+ ATPase Apoptosis
  3. Citreoviridin

Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells.

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Citreoviridin Chemical Structure

Citreoviridin Chemical Structure

CAS No. : 25425-12-1

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Description

Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner[1]. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells[2].

IC50 & Target

Na+/K+-ATPase[1]
Apoptosis[2]

Molecular Weight

402.48

Formula

C23H30O6

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC(/C=C/C=C/C=C/C(O1)=C(C(OC)=CC1=O)C)=C\[C@]2([C@H](O)[C@]([C@H](O2)C)(O)C)C

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Citreoviridin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Citreoviridin
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HY-N6745
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