Search Result

Results for "

WA 0859 3970 0884 Anggaran Pembuatan Interior Rumah Dan Harga Berpengalaman Laweyan Solo

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (4) Antibiotic (2) Apoptosis (4) Bacterial (3) Biochemical Assay Reagents (3) Caspase (2) DNA/RNA Synthesis (2) Dopamine Receptor (7) Endothelin Receptor (1) Enterovirus (1) FABP (4) Fluorescent Dye (1) Fungal (2) HIV (2) Isotope-Labeled Compounds (1) Keap1-Nrf2 (2) Microtubule/Tubulin (2) Mitochondrial Metabolism (2) NF-κB (2) Reactive Oxygen Species (ROS) (2) Reference Standards (4) SARS-CoV (2) Topoisomerase (1) VEGFR (2)
By Research Areas:	Cancer (8) Cardiovascular Disease (10) Infection (10) Inflammation/Immunology (2) Metabolic Disease (10) Neurological Disease (9)

By Targets:

5-HT Receptor (4)

Antibiotic (2)

Apoptosis (4)

Bacterial (3)

Biochemical Assay Reagents (3)

Caspase (2)

DNA/RNA Synthesis (2)

Dopamine Receptor (7)

Endothelin Receptor (1)

Enterovirus (1)

FABP (4)

Fluorescent Dye (1)

Fungal (2)

HIV (2)

Isotope-Labeled Compounds (1)

Keap1-Nrf2 (2)

Microtubule/Tubulin (2)

Mitochondrial Metabolism (2)

NF-κB (2)

Reactive Oxygen Species (ROS) (2)

Reference Standards (4)

SARS-CoV (2)

Topoisomerase (1)

VEGFR (2)

By Research Areas:

Cancer (8)

Cardiovascular Disease (10)

Infection (10)

Inflammation/Immunology (2)

Metabolic Disease (10)

Neurological Disease (9)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Dan family

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-N0135

Tanshinone IIA Maximum Cited Publications 36 Publications Verification Dan Shen ketone	VEGFR	Cardiovascular Disease Cancer
Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.

HY-101903

BMS-309403 20+ Cited Publications	FABP	Cardiovascular Disease Metabolic Disease
BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with K_is of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

HY-N1913

Danshensu 5+ Cited Publications Dan shen suan A; Salvianic acid A	Keap1-Nrf2 NF-κB Reactive Oxygen Species (ROS) SARS-CoV Apoptosis	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Danshensu (Dan shen suan A), an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu displays a potent antiviral activity against SARS-CoV-2 with EC₅₀ of 0.97 μM. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .

HY-101903A

BMS-309403 sodium 20+ Cited Publications	FABP	Cardiovascular Disease Metabolic Disease
BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with K_is of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

HY-130412

FlAsH-EDT2 2 Publications Verification	Fluorescent Dye	Others
FlAsH-EDT2 is a protein labeling reagent. FlAsH-EDT2 binds to Cys4 with high affinity and emits fluorescence. FlAsH-EDT2 can cross the cell membrane and enter the interior of the cell. FlAsH-EDT2 can only be used for labeling proteins with high concentration .

HY-14545

Amisulpride 2 Publications Verification (Rac)-Aramisulpride; (Rac)-Esamisulpride; Dan 2163	Dopamine Receptor 5-HT Receptor	Neurological Disease
Amisulpride ((Rac)-Aramisulpride) is a racemic (50:50) mixture of the R-Amisulpride (HY-109167) and S-Amisulpride (HY-126068). Amisulpride is a dopamine D₂/D₃ receptor antagonist with K_i values of 2.8 and 3.2 nM for human dopamine b>D₂ and b>D₃, respectively. Amisulpride is a 5-HT₇ receptor antagonist with a K_i of 44 nM. Amisulpride can be used in psychiatric research .

HY-N7543

Schisantherin D	HIV Endothelin Receptor	Infection Metabolic Disease
Schisantherin D is a lignan. Schisantherin D can be isolated from Kadsura interior. Schisantherin D downregulates the expression of ETBR and inhibits the secretion of ECM and ET-1. Schisantherin D alleviates EtOH + ET-1-induced hepatocyte cytotoxicity. Schisantherin D potently inhibits HIV replication in cells .

HY-126068

Esamisulpride (S)-Amisulpride; (S)-Aramisulpride; (S)-Dan 2163	Dopamine Receptor 5-HT Receptor	Neurological Disease
Esamisulpride ((S)-Amisulpride) is the S-isomer of Amisulpride (HY-14545). Esamisulpride is a potent dopamine D₂/D₃ receptor antagonist with K_i values of 4.43 nM for D₂R and 0.72 nM for D₃R. Esamisulpride is a 5-HT₇ receptor antagonist with a K_i of 900 nM. Esamisulpride can be used in the research of schizophrenia and depression .

HY-N1913A

Danshensu sodium 5+ Cited Publications Dan shen suan A sodium; Salvianic acid A sodium	Keap1-Nrf2 NF-κB Reactive Oxygen Species (ROS) SARS-CoV Apoptosis	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Danshensu (Dan shen suan A) sodium, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu sodium reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu sodium displays a potent antiviral activity against SARS-CoV-2 with EC₅₀ of 0.97 μM. Danshensu sodium has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .

HY-14545A

Amisulpride hydrochloride 2 Publications Verification (Rac)-Aramisulpride hydrochloride; (Rac)-Esamisulpride hydrochloride; (Rac)-Dan 2163 hydrochloride	Dopamine Receptor	Neurological Disease
Amisulpride hydrochloride is a dopamine D₂/D₃ receptor antagonist with K_is of 2.8 and 3.2 nM for human dopamine D₂ and D₃, respectively.

HY-109167

Aramisulpride (R)-Amisulpride; (R)-Esamisulpride; (R)-Dan 2163	Dopamine Receptor 5-HT Receptor	Neurological Disease
Aramisulpride (R-(+)-Amisulpride) is the R-isomer of Amisulpride (HY-14545). Aramisulpride is a 5-HT₇ receptor antagonist with a K_i value of 22 nM. Aramisulpride is a D₂/D₃ receptor antagonist with a K_i value of 140 nM for D₂R and a K_i value of 13.9 nM for D₃R. Aramisulpride can be used in psychiatric research .

HY-P5345

KLA peptide	Apoptosis Antibiotic Caspase Mitochondrial Metabolism	Cardiovascular Disease Infection Neurological Disease Metabolic Disease
KLA peptide is a naturally occurring Antibiotic peptide that is nontoxic outside of cells but is toxic when it enters into the interior of targeted cells. KLA peptide can induce cell Apoptosis by disrupting mitochondrial membranes and activating Caspase. MG1-KLA, formed by the coupling of KLA peptide with MG1, can selectively induce apoptosis in pro-inflammatory microglia. KLA peptide can be used for the research of liver fibrosis. KLA peptide can be used for the research of neonatal hypoxic-ischemic encephalopathy.

HY-14545S

Amisulpride-d5 (Rac)-Aramisulpride-d₅; (Rac)-Esamisulpride-d₅; Dan 2163-d₅	Dopamine Receptor	Neurological Disease Cancer
Amisulpride-d₅ is the deuterium labeled Amisulpride. Amisulpride is a dopamine D2/D3 receptor antagonist with K_is of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively .

HY-143498

ERCC1-XPF-IN-1	DNA/RNA Synthesis	Cancer
ERCC1-XPF-IN-1 is a potent and high-affinity ERCC1-XPF inhibitor with IC₅₀ value of 0.49 μM. ERCC1-XPF-IN-1 has the capacity to potentiate the cytotoxicity effect of UV radiation and inhibiting DAN repair, by the inhibition of removal of CPDs, and cyclophosphamide toxicity to colorectal cancer cells .

HY-107492

Ethaboxam Intego Solo	Microtubule/Tubulin Fungal	Infection
Ethaboxam is a β-tubulin inhibitor that can be used as anti-oomycete fungicide .

HY-111233

Disoxaril WIN-51711	Enterovirus	Infection
Disoxaril (WIN-51711) is an antivirus agent with activity against poliovirus types 1 and 2. Disoxaril inserts into the hydrophobic interior of virus capsid protein VP1 to stabilize virion conformation, inhibits poliovirus uncoating, and prevents viral RNA release and synthesis. Disoxaril can be used for the research of poliovirus infection .

HY-23206

DAN-1 EE hydrochloride	Biochemical Assay Reagents	Others
DAN-1 EE hydrochloride is a fluorescent indicator, which can be used for the detection of nitrite content in vitro and biological process .

HY-N0135R

Tanshinone IIA (Standard) Dan Shen ketone (Standard)	Reference Standards VEGFR	Cardiovascular Disease Cancer
Tanshinone IIA (Standard) is the analytical standard of Tanshinone IIA. This product is intended for research and analytical applications. Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.

HY-122307

Sulisatin Dan-603	Bacterial	Metabolic Disease
Sulisatin (DAN-603) is an anionic laxative that is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon during oral administration .

HY-122307A

Sulisatin disodium Dan-603 disodium	Bacterial	Metabolic Disease
Sulisatin (DAN-603) disodium is an anionic diarrhea-promoting compound. During oral administration, Sulisatin disodium is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon .

HY-W705792

Ethaboxam-d5 Intego Solo-d₅	Isotope-Labeled Compounds Microtubule/Tubulin Fungal	Infection
Ethaboxam-d₅ (Intego solo-d₅) is the deuterium labeled Ethaboxam (HY-107492). Ethaboxam is a β-tubulin inhibitor that can be used as anti-oomycete fungicide .

HY-N12379

Interiotherin D	Others	Others
Interiotherin D is a lignan that can be isolated from Kadsura interior .

HY-109167A

Aramisulpride hydrochloride (R)-Amisulpride hydrochloride; (R)-Esamisulpride hydrochloride; (R)-Dan 2163 hydrochloride	Dopamine Receptor 5-HT Receptor	Neurological Disease
Aramisulpride hydrochloride is a 5-HT₇ receptor antagonist with a K_i value of 22 nM. Aramisulpride hydrochloride is a D₂/D₃ receptor antagonist with a K_i value of 140 nM for D₂R and a K_i value of 13.9 nM for D₃R. Aramisulpride hydrochloride can be used in psychiatric research .

HY-14545R

Amisulpride (Standard) (Rac)-Aramisulpride (Standard); (Rac)-Esamisulpride (Standard); Dan 2163 (Standard)	Reference Standards Dopamine Receptor	Neurological Disease Cancer
Amisulpride (Standard) is the analytical standard of Amisulpride. This product is intended for research and analytical applications. Amisulpride is a dopamine D₂/D₃ receptor antagonist with K_is of 2.8 and 3.2 nM for human dopamine D₂ and D₃, respectively.

HY-N6849

InteriotherinA	HIV	Infection Metabolic Disease
Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent .

HY-134924

Succinyl-β-cycloaltrin	Biochemical Assay Reagents	Others
Succinyl-β-cycloaltrin is a modified cyclodextrin with unique chemical properties that make it an effective solubilizer and stabilizer for various compounds, especially in the pharmaceutical industry. Succinyl-β-cycloaltrin has a hydrophobic interior and a hydrophilic exterior, enabling it to form stable clathrates with hydrophobic molecules such as drugs and nutrients. This increases their solubility and bioavailability, making them more effective for recreational or nutritional purposes.

HY-101903R

BMS-309403 (Standard)	Reference Standards FABP	Cardiovascular Disease Metabolic Disease
BMS-309403 (Standard) is the analytical standard of BMS-309403. This product is intended for research and analytical applications. BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

HY-101903AR

BMS-309403 sodium (Standard)	Reference Standards FABP	Cardiovascular Disease Metabolic Disease
BMS-309403 (sodium) (Standard) is the analytical standard of BMS-309403 (sodium). This product is intended for research and analytical applications. BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .

HY-N6914

Nortanshinone	Others	Cancer
Nortanshinone is a pigment isolated from Dan-Shen .

HY-N17848

Ethyl lithospermate	Others	Others
Ethyl lithospermate is a phenolic compound found in the dried root of Radix Salvia miltiorrhizae (Dan-shen) .

HY-182816

Topoisomerase I-IN-22	Topoisomerase DNA/RNA Synthesis Bacterial	Infection
Topoisomerase I-IN-22 is an inhibitor of MRSA DNA Topoisomerase I with an IC₅₀ of 0.85 μg/mL. Topoisomerase I-IN-22 can specifically disrupt the cell membrane structure of MRSA, enter the interior of bacteria and inhibit the activity of DNA Topoisomerase I, thereby interfering with the processes of DNA replication and transcription. Topoisomerase I-IN-22 can be used for the research of MRSA infection .

HY-170466

16:0-12 Doxyl PC 1-Palmitoyl-2-stearoyl-(12-doxyl)-sn-glycero-3-phosphocholine	Biochemical Assay Reagents	Others
16:0-12 Doxyl PC (1-Palmitoyl-2-stearoyl-(12-doxyl)-sn-glycero-3-phosphocholine) is a fluorescence quencher, and its nitrogen oxide is located downstream of the sn-2 chain. 16:0-12 Doxyl PC has a better fluorescence quenching effect onthe fluorophore is buried within the hydrocarbon interior of the bilayer .

HY-P5345A

KLA peptide acetate	Apoptosis Antibiotic Caspase Mitochondrial Metabolism	Cardiovascular Disease Infection Neurological Disease Metabolic Disease
KLA peptide acetate is a naturally occurring Antibiotic peptide that is nontoxic outside of cells but is toxic when it enters into the interior of targeted cells. KLA peptide acetate can induce cell Apoptosis by disrupting mitochondrial membranes and activating Caspase. MG1-KLA acetate, formed by the coupling of KLA peptide acetate with MG1, can selectively induce apoptosis in pro-inflammatory microglia. KLA peptide acetate can be used for the research of liver fibrosis. KLA peptide acetate can be used for the research of neonatal hypoxic-ischemic encephalopathy .

Cat. No.	상품명

HY-L920

CNS MPO Lead-like Library	24,816 compounds
With the aging population and increasing competitive pressures, neurodegenerative diseases of the central nervous system (CNS) have become a serious medical challenge in modern society, including Parkinson's disease, Alzheimer's disease, brain tumors, and multiple sclerosis. The CNS MPO (Multi-Parameter Optimization) score is a widely recognized algorithm in medicinal chemistry. Developed by Pfizer, this method is based on an analysis of approved CNS drugs and their interior CNS drug candidates, establishing the CNS MPO rules. It incorporates six key physicochemical properties (ClogP, ClogD, MW, TPSA, HBD, and pKa) to prospectively optimize CNS drug attributes—such as high blood-brain barrier (BBB) permeability, low P-gp efflux liability, low metabolic clearance, and high safety—thereby improving the clinical success rate of CNS drug candidates. The CNS MPO compound library is a collection of compounds with CNS MPO scores greater than 5, specifically designed for CNS drug discovery.

CNS MPO Lead-like Library

24,816 compounds

HY-L211

Human Hormone Compound Library	87 compounds
Hormones are a class of biologically active substances secreted by endocrine gland cells, which are transported through the circulatory system to various parts of the body, and precisely act on specific target organs or cells, playing a crucial role in regulating the growth, development, metabolism, and reproduction of organisms. The mechanisms of hormone action are diverse and complex. Some hormones (such as corticosteroids, vitamin D, and thyroid hormones) can enter the cell interior and interact with receptors in the nucleus, thereby regulating gene expression and affecting cell function. Other hormones (such as growth hormone and thyrotropin-releasing hormone) bind directly to receptors on the cell surface, exerting their effects by regulating enzyme activity or influencing the state of ion channels. Additionally, hormones play a key role in the study of endocrine and metabolic diseases, and are closely related to the development of diseases such as diabetes and thyroid diseases. MCE has included 87 human hormone compounds, which is of great significance for the study of human metabolic pathways, and can also be used to build a metabonomics database.

Human Hormone Compound Library

87 compounds

Hormones are a class of biologically active substances secreted by endocrine gland cells, which are transported through the circulatory system to various parts of the body, and precisely act on specific target organs or cells, playing a crucial role in regulating the growth, development, metabolism, and reproduction of organisms. The mechanisms of hormone action are diverse and complex. Some hormones (such as corticosteroids, vitamin D, and thyroid hormones) can enter the cell interior and interact with receptors in the nucleus, thereby regulating gene expression and affecting cell function. Other hormones (such as growth hormone and thyrotropin-releasing hormone) bind directly to receptors on the cell surface, exerting their effects by regulating enzyme activity or influencing the state of ion channels. Additionally, hormones play a key role in the study of endocrine and metabolic diseases, and are closely related to the development of diseases such as diabetes and thyroid diseases.

MCE has included 87 human hormone compounds, which is of great significance for the study of human metabolic pathways, and can also be used to build a metabonomics database.

HY-L919

MCE CNS BBB Lead-like Library	27,503 compounds
With the aging population and increasing competitive pressures, neurodegenerative diseases of the central nervous system (CNS) have become a serious medical challenge in modern society, including Parkinson's disease, Alzheimer's disease, brain tumors, and multiple sclerosis. However, the success rate of CNS drug development remains remarkably low, primarily due to the blood-brain barrier (BBB). The blood-brain barrier (BBB) is a semipermeable barrier structure that surrounds the microvasculature of the CNS. In capillaries, the wedged endothelial cells are tightly packed and wedge-shaped, lining the interior of the vessels to form extensive tight junctions. Along with a range of receptors, transporters, efflux pumps, and other cellular components, this barrier regulates the entry and exit of molecules between the bloodstream and the brain. The intact BBB blocks the passage of most blood-borne substances into the brain, preventing nearly 100% of large-molecule drugs and over 98% of small-molecule drugs from entering. Compared to non-CNS drugs, physicochemical properties such as hydrogen bonds, lipophilicity, and molecular weight significantly influence a compound's ability to cross the BBB. Using artificial intelligence (AI) algorithms to predict BBB permeability, a predicted value greater than 0.75 indicates that the compound has strong potential to cross the BBB, providing a promising starting point for CNS drug discovery.

MCE CNS BBB Lead-like Library

27,503 compounds

With the aging population and increasing competitive pressures, neurodegenerative diseases of the central nervous system (CNS) have become a serious medical challenge in modern society, including Parkinson's disease, Alzheimer's disease, brain tumors, and multiple sclerosis. However, the success rate of CNS drug development remains remarkably low, primarily due to the blood-brain barrier (BBB). The blood-brain barrier (BBB) is a semipermeable barrier structure that surrounds the microvasculature of the CNS. In capillaries, the wedged endothelial cells are tightly packed and wedge-shaped, lining the interior of the vessels to form extensive tight junctions. Along with a range of receptors, transporters, efflux pumps, and other cellular components, this barrier regulates the entry and exit of molecules between the bloodstream and the brain. The intact BBB blocks the passage of most blood-borne substances into the brain, preventing nearly 100% of large-molecule drugs and over 98% of small-molecule drugs from entering. Compared to non-CNS drugs, physicochemical properties such as hydrogen bonds, lipophilicity, and molecular weight significantly influence a compound's ability to cross the BBB. Using artificial intelligence (AI) algorithms to predict BBB permeability, a predicted value greater than 0.75 indicates that the compound has strong potential to cross the BBB, providing a promising starting point for CNS drug discovery.

Cat. No.	상품명	Type

HY-134924

Succinyl-β-cycloaltrin	Biochemical Assay Reagents
Succinyl-β-cycloaltrin is a modified cyclodextrin with unique chemical properties that make it an effective solubilizer and stabilizer for various compounds, especially in the pharmaceutical industry. Succinyl-β-cycloaltrin has a hydrophobic interior and a hydrophilic exterior, enabling it to form stable clathrates with hydrophobic molecules such as drugs and nutrients. This increases their solubility and bioavailability, making them more effective for recreational or nutritional purposes.

Succinyl-β-cycloaltrin

Biochemical Assay Reagents

Succinyl-β-cycloaltrin is a modified cyclodextrin with unique chemical properties that make it an effective solubilizer and stabilizer for various compounds, especially in the pharmaceutical industry. Succinyl-β-cycloaltrin has a hydrophobic interior and a hydrophilic exterior, enabling it to form stable clathrates with hydrophobic molecules such as drugs and nutrients. This increases their solubility and bioavailability, making them more effective for recreational or nutritional purposes.

HY-170466

16:0-12 Doxyl PC 1-Palmitoyl-2-stearoyl-(12-doxyl)-sn-glycero-3-phosphocholine	Biochemical Assay Reagents
16:0-12 Doxyl PC (1-Palmitoyl-2-stearoyl-(12-doxyl)-sn-glycero-3-phosphocholine) is a fluorescence quencher, and its nitrogen oxide is located downstream of the sn-2 chain. 16:0-12 Doxyl PC has a better fluorescence quenching effect onthe fluorophore is buried within the hydrocarbon interior of the bilayer .

Cat. No.	상품명	Target	Research Area

HY-P5345

KLA peptide	Apoptosis Antibiotic Caspase Mitochondrial Metabolism	Cardiovascular Disease Infection Neurological Disease Metabolic Disease
KLA peptide is a naturally occurring Antibiotic peptide that is nontoxic outside of cells but is toxic when it enters into the interior of targeted cells. KLA peptide can induce cell Apoptosis by disrupting mitochondrial membranes and activating Caspase. MG1-KLA, formed by the coupling of KLA peptide with MG1, can selectively induce apoptosis in pro-inflammatory microglia. KLA peptide can be used for the research of liver fibrosis. KLA peptide can be used for the research of neonatal hypoxic-ischemic encephalopathy.

HY-P5345A

KLA peptide acetate	Apoptosis Antibiotic Caspase Mitochondrial Metabolism	Cardiovascular Disease Infection Neurological Disease Metabolic Disease
KLA peptide acetate is a naturally occurring Antibiotic peptide that is nontoxic outside of cells but is toxic when it enters into the interior of targeted cells. KLA peptide acetate can induce cell Apoptosis by disrupting mitochondrial membranes and activating Caspase. MG1-KLA acetate, formed by the coupling of KLA peptide acetate with MG1, can selectively induce apoptosis in pro-inflammatory microglia. KLA peptide acetate can be used for the research of liver fibrosis. KLA peptide acetate can be used for the research of neonatal hypoxic-ischemic encephalopathy .

Cat. No.	상품명	Category	Target	Chemical Structure

HY-N0135

Tanshinone IIA Maximum Cited Publications 36 Publications Verification Dan Shen ketone	Quinones Classification of Application Fields Terpenoids Labiatae Samanea saman (Jacq.) Merr. Diterpenoids Plants Naphthalene Quinones Disease Research Fields Source Classification Cancer	VEGFR
Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.

HY-N1913

Danshensu 5+ Cited Publications Dan shen suan A; Salvianic acid A	Classification of Application Fields Simple Phenylpropanols Labiatae Samanea saman (Jacq.) Merr. Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Source Classification Cancer	Keap1-Nrf2 NF-κB Reactive Oxygen Species (ROS) SARS-CoV Apoptosis
Danshensu (Dan shen suan A), an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu displays a potent antiviral activity against SARS-CoV-2 with EC₅₀ of 0.97 μM. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .

HY-N7543

Schisantherin D	Schisandra sphenanthera Rehd. et Wils Infection Structural Classification Classification of Application Fields Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Source Classification	HIV Endothelin Receptor
Schisantherin D is a lignan. Schisantherin D can be isolated from Kadsura interior. Schisantherin D downregulates the expression of ETBR and inhibits the secretion of ECM and ET-1. Schisantherin D alleviates EtOH + ET-1-induced hepatocyte cytotoxicity. Schisantherin D potently inhibits HIV replication in cells .

HY-N1913A

Danshensu sodium 5+ Cited Publications Dan shen suan A sodium; Salvianic acid A sodium	Simple Phenylpropanols Labiatae Samanea saman (Jacq.) Merr. Phenols Polyphenols Phenylpropanoids Plants Source Classification	Keap1-Nrf2 NF-κB Reactive Oxygen Species (ROS) SARS-CoV Apoptosis
Danshensu (Dan shen suan A) sodium, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu sodium reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu sodium displays a potent antiviral activity against SARS-CoV-2 with EC₅₀ of 0.97 μM. Danshensu sodium has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .

HY-N0135R

Tanshinone IIA (Standard) Dan Shen ketone (Standard)	Quinones Structural Classification Terpenoids Labiatae Samanea saman (Jacq.) Merr. Diterpenoids Plants Naphthalene Quinones Source Classification	Reference Standards VEGFR
Tanshinone IIA (Standard) is the analytical standard of Tanshinone IIA. This product is intended for research and analytical applications. Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.

HY-N12379

Interiotherin D	Kadsura heteroclita (Roxb.) Craib Lignans Phenylpropanoids Plants Schisandraceae Source Classification	Others
Interiotherin D is a lignan that can be isolated from Kadsura interior .

HY-N6849

InteriotherinA	Classification of Application Fields Lignans Metabolic Disease Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields Source Classification	HIV
Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent .

HY-N6914

Nortanshinone	Quinones Classification of Application Fields Labiatae Samanea saman (Jacq.) Merr. Pigments Plants Naphthalene Quinones Disease Research Fields Cancer Food Research Source Classification	Others
Nortanshinone is a pigment isolated from Dan-Shen .

HY-N17848

Ethyl lithospermate	Structural Classification Labiatae Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Source Classification	Others
Ethyl lithospermate is a phenolic compound found in the dried root of Radix Salvia miltiorrhizae (Dan-shen) .

Species:	Human (4) Mouse (2)
Tag:	His (4) Tag Free (1) Fc (1)
Source:	HEK293 (4) Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	상품명	Species	Source	Image

HY-P79104

	PRDC/GREM2 Protein, Mouse Gremlin-2; Grem2; Cysteine knot superfamily 1, BMP antagonist 2; Protein related to Dan and cerberus; PRDC; Cktsf1b2; Protein Related to Dan and Cerberus/Gremlin-2	Mouse	E. coli
	PRDC, encoded by the GREM2 gene, has multiple functions, including BMP and protein binding, which are critical for dorsal identity determination, embryoid body morphogenesis, and signal transduction regulation. PRDC is found extracellularly and is expressed in structures such as the cartilaginous skull, integument, intestinal smooth muscle annulus, lung, and neural tube. PRDC/GREM2 Protein, Mouse is the recombinant mouse-derived PRDC/GREM2 protein, expressed by E. coli , with tag free.

HY-P75350

	Cerberus 1/CER1 Protein, Human (sf9, His) Cerberus; Dan domain family member 4; CER1; DanD4	Human	Sf9 insect cells
	The Cerberus 1/CER1 protein emerges as a cytokine that may be involved in preneural induction and somite formation during embryogenesis, in part through its inhibitory effect on BMP signaling. Its regulatory role extends into gastrulation, where it can influence nodal signaling and contribute to primitive streak formation and patterning. Cerberus 1/CER1 Protein, Human (sf9, His) is the recombinant human-derived Cerberus 1/CER1 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P74736

	NBL1 Protein, Human (HEK293, His) Neuroblastoma suppressor of tumorigenicity 1; Protein N03; NBL1; Dan; DanD1	Human	HEK293
	NBL1 protein, identified as a potential tumor suppressor gene in neuroblastoma, plays a crucial role in inhibiting cells from progressing into the critical G1/S stage of the transformation process. Functioning as a homodimer, NBL1 underscores its involvement in regulatory mechanisms governing cellular transformation and emphasizes its potential contributions to maintaining normal cellular growth control. NBL1 Protein, Human (HEK293, His) is the recombinant human-derived NBL1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74737

	NBL1 Protein, Human (HEK293, Fc) Neuroblastoma suppressor of tumorigenicity 1; Protein N03; NBL1; Dan; DanD1	Human	HEK293
	NBL1 protein, identified as a potential tumor suppressor gene in neuroblastoma, plays a crucial role in inhibiting cells from progressing into the critical G1/S stage of the transformation process. Functioning as a homodimer, NBL1 underscores its involvement in regulatory mechanisms governing cellular transformation and emphasizes its potential contributions to maintaining normal cellular growth control. NBL1 Protein, Human (HEK293, Fc) is the recombinant human-derived NBL1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P7822

	Cerberus 1/CER1 Protein, Human (HEK293, His) 1 Publications Verification rHuCerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)/CER1, His; Cerberus; Cerberus-Related Protein; Dan Domain Family Member 4; CER1; DanD4	Human	HEK293
	The CER1 protein, a DAN family BMP antagonist, coordinates growth-promoting ureteric bud signaling by inducing BMP inhibition. CER1 also regulates embryogenesis and carcinogenesis by inhibiting NODAL signaling to SMAD2 or SMAD3 through ALK4/ALK7. Cerberus 1/CER1 Protein, Human (HEK293, His) is the recombinant human-derived Cerberus 1/CER1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70076

	NBL1 Protein, Mouse (HEK293, His) rMuNeuroblastoma suppressor of tumorigenicity 1/DanD1, His; DanD1; NBL1; Dan domain family member 1; neuroblastoma suppressor of tumorigenicity 1; Protein N03; suppression of tumorigenicity 1	Mouse	HEK293
	DAND1 protein, identified as a potential tumor suppressor gene in neuroblastoma, plays a pivotal role in inhibiting cells from progressing into the crucial G1/S stage of the transformation process.As a homodimer, DAND1 underscores its involvement in regulatory mechanisms governing cellular transformation and contributing to the maintenance of normal cellular growth control.NBL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DAND1 protein, expressed by HEK293 , with C-6*His labeled tag.

Compare Products


Products	해외재고보유 - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

Cat. No.	상품명	Chemical Structure

HY-14545S

Amisulpride-d5
Amisulpride-d₅ is the deuterium labeled Amisulpride. Amisulpride is a dopamine D2/D3 receptor antagonist with K_is of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively .

HY-W705792

Ethaboxam-d5
Ethaboxam-d₅ (Intego solo-d₅) is the deuterium labeled Ethaboxam (HY-107492). Ethaboxam is a β-tubulin inhibitor that can be used as anti-oomycete fungicide .

Host:	Mouse (6)
Reactivity:	Human (5) Rat (5) Mouse (5)
Application:	IHC-P (5) ICC/IF (3) WB (2) ELISA (1)
Isotype:	IgG1 (3) IgG2a (2)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	상품명	Application	Reactivity	Image

HY-P88564

	*SESTD1 (Solo) Antibody (YA8248)* Solo	IHC-P, ICC/IF	Human, Mouse, Rat
	SESTD1 (Solo) Antibody (YA8248) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SESTD1 (Solo).

HY-P88564A

	*SESTD1 (Solo) Antibody (YA8248)(PBS only)* Solo	IHC-P, ICC/IF	Human, Mouse, Rat
	SESTD1 (Solo) Antibody (YA8248) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SESTD1 (Solo).

HY-P88123

	PARN Antibody (YA7807) Dan	IHC-P	Human, Mouse, Rat
	PARN Antibody (YA7807) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PARN.

HY-P88123A

	PARN Antibody (YA7807)(PBS only) Dan	IHC-P	Human, Mouse, Rat
	PARN Antibody (YA7807) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PARN.

HY-P85099

	Cerberus Antibody (YA4791) CER1; DanD4; Cerberus; Cerberus-related protein; Dan domain family member 4	WB, IHC-P, ICC/IF, ELISA	Human
	Cerberus Antibody (YA4791) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cerberus.

HY-P86948

	LRP4 Antibody (YA6641) KIAA0816 antibody; LDLR Dan antibody; Low density lipoprotein receptor related protein 4 antibody; Low-density lipoprotein receptor-related protein 4 antibody; LRP-4 antibody; LRP10 antibody; Lrp4 antibody; LRP4_HUMAN antibody; MEGF7 antibody; Multiple epidermal growth factor like domains 7 antibody; KIAA0816 antibody; LDLR Dan antibody; Low density lipoprotein receptor related protein 4 antibody; Low-density lipoprotein receptor-related protein 4 antibody; LRP-4 antibody; LRP10 antibody; Lrp4 antibody; LRP4_HUMAN antibody; MEGF7 antibody; Multiple epidermal growth factor like domains 7 antibody; Multiple epidermal growth factor-like domains 7 antibody;	WB	Mouse, Rat
	LRP4 Antibody (YA6641) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LRP4.

Compare Products


Products	해외재고보유 - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

온라인 문의

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
호칭			Country or Region *
고객명 *			회사명 *
Department *
메일주소 *			상품명 *
Cat. No.			Requested quantity *
전화번호 *
비고

온라인 문의

Inquiry Information

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

WA 0859 3970 0884 Anggaran Pembuatan Interior Rumah Dan Harga Berpengalaman Laweyan Solo

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Natural
Products