SESTD1 (Solo) Antibody (YA8248)
(Synonyms: SOLO)SESTD1 (Solo) Antibody (YA8248) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SESTD1 (Solo).
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Host:
Mouse
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Isotype:
IgG
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 |
Product Details
SESTD1 (Solo) Antibody (YA8248) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SESTD1 (Solo).
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 79.2 kDa
Full length human recombinant protein of human SESTD1 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SESTD1 may act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1
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Expression
Tissue_Specificity: Broad expression. High expression in thalamus and brain. Significantly expressed in vasculature -
Isoforms & Post-Translational Modification
Q86VW0: 696 amino acids, molecular weight 79348 Da.
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Subunit
Interacts (via the spectrin 1 repeat) with TRPC4 and TRPC5 (via CIRB domain)
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SwissProt ID
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Synonyms
SOLO
Documentation
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