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antifungal metabolite

" in MedChemExpress (MCE) Product Catalog:

68

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3

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40

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6

Isotope-Labeled Compounds

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Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-113219
    Hydroxyphenyllactic acid
    1 Publications Verification

    		 Endogenous Metabolite Fungal Infection
    Hydroxyphenyllactic acid is an antifungal metabolite.
    Hydroxyphenyllactic acid
  • HY-100711
    Prodigiosin
    3 Publications Verification

    Prodigiosine; NSC47147

    		 Bacterial Apoptosis Wnt Fungal Parasite Infection Inflammation/Immunology Cancer
    Prodigiosin (Prodigiosine) is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin is a potent inhibitor of the Wnt/β-catenin pathway. Prodigiosin has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
    Prodigiosin
  • HY-P1939
    Cyclo(L-Leu-L-Pro)

    Cyclo(L-prolyl-L-leucyl)

    		 Fungal Bacterial Influenza Virus Infection
    Cyclo(L-Leu-L-Pro) is a cyclic dipeptide with broad-spectrum antibacterial, antiviral and antifungal activities. Its biological activity is highly dependent on the stereoconfiguration and is widely present in microbial metabolites. Cyclo(L-Leu-L-Pro) efficiently and specifically inhibits the production of aflatoxin by Aspergillus flavus. The cis configuration of Cyclo(L-Leu-L-Pro) (cis-cyclo(L-Leu-L-Pro)) has broad-spectrum antibacterial activity against multi-drug resistant bacteria and significantly inhibits the influenza A virus H3N2 .
    Cyclo(L-Leu-L-Pro)
  • HY-116637
    Tetrahydromagnolol

    Magnolignan

    		 Cannabinoid Receptor GPR55 Drug Metabolite Infection Neurological Disease Inflammation/Immunology
    Tetrahydromagnolol (Magnolignan), the main metabolite of Magnolol, is a potent and selective cannabinoidCB2 receptor agonist (EC50 =170 nM) and GPR55 antagonist. The Ki of Tetrahydromagnolol for CB2 is 416 nM, 20-fold higher than for the CB1 receptor. Magnolol shows antifungal, anti-inflammatory and analgesic effects .
    Tetrahydromagnolol
  • HY-B0277
    Vidarabine
    Maximum Cited Publications
    7 Publications Verification

    Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine

    		 Apoptosis Fungal Reactive Oxygen Species (ROS) EBV HSV Antibiotic DNA/RNA Synthesis Drug Metabolite Infection Cancer
    Vidarabine (Ara-A) is a nucleoside antibiotic isolated from Streptomyces, and a metabolite of Vidarabine phosphate (HY-B0277A). Vidarabine selectively inhibits viral DNA polymerase and cellular ribonucleotide reductase, thereby blocking viral replication. Vidarabine phosphate also exhibits antifungal activity, induces late-stage cellular apoptosis, and causes cell cycle arrest. Vidarabine phosphate can be used in research related to severe chronic active Epstein-Barr virus (EBV) infection, herpes infection, and candidiasis .
    Vidarabine
  • HY-12772
    Hydroxy Itraconazole

    R-63373

    		 Fungal Drug Metabolite Others
    Hydroxy Itraconazole (R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
    Hydroxy Itraconazole
  • HY-N0926
    Columbamine
    1 Publications Verification

    Columbamin; Dehydroisocorypalmine

    		 Cytochrome P450 Apoptosis Parasite Infection Neurological Disease Inflammation/Immunology Cancer
    Columbamine (Columbamin; Dehydroisocorypalmine) is an organic heterotetracyclic alkaloid extracted from plants. Columbamine is a metabolite of Berberine (HY-N0716). Columbamine inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 30.6 µM). Columbamine induces apoptosis in cancer cells. Columbamine can be used for antioxidant, anti-inflammatory, antitumor, antifungal, antiparasite, hepatoprotective, neuroprotective, hypolipidemic and hypoglycemic study .
    Columbamine
  • HY-12772S
    Hydroxy Itraconazole-d8

    R-63373-d8

    		 Fungal Infection
    Hydroxy Itraconazole-d8 is the deuterium labeled Hydroxy Itraconazole (HY-12772). Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
    Hydroxy Itraconazole-d8
  • HY-W010435
    Sulcatone

    6-Methyl-5-hepten-2-one

    		 Environmental Pollutants Parasite Endogenous Metabolite Adenosine Receptor Fungal Cytochrome P450 Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Sulcatone (6-Methyl-5-hepten-2-one) is a plant-derived volatile organic compound with activities such as insecticidal, antifungal, and blood pressure-lowering effects. Sulcatone also serves as an insect pheromone and an endogenous metabolite, which can be found in feces. Changes in Sulcatone levels can be used for the auxiliary diagnosis of ulcerative colitis .
    Sulcatone
  • HY-N6027
    Cyclosporin C

    		Fungal Bacterial Infection
    Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal, antiviral, and immunosuppressant properties. Cyclosporin C shows no activity against bacteria or yeasts .
    Cyclosporin C
  • HY-136767
    Cladosporin

    		Antibiotic Fungal Bacterial Parasite DNA/RNA Synthesis Infection
    Cladosporin is an antibiotic and an an antifungal metabolite that can be produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin exhibits inhibitory activity against various dermatophytes, plant pathogens, and bacteria. Cladosporin also exhibits antimalarial activity through inhibition of cytoplasmic lysine-tRNA synthetase of Plasmodium (PfKrs1) .
    Cladosporin
  • HY-113430
    5-n-Heneicosylresorcinol

    5-Heneicosylresorcinol

    		 Fungal Infection
    5-n-Heneicosylresorcinol (5-Heneicosylresorcinol) is an active n-alkyl(enyl)resorcinols (AR) occurring in cereal products from Colombia. Antifungal activity .
    5-n-Heneicosylresorcinol
  • HY-W016203
    Phenylpyruvic acid sodium

    Sodium phenylpyruvate

    		 Endogenous Metabolite PDI Infection Metabolic Disease
    Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity .
    Phenylpyruvic acid sodium
  • HY-N0926A
    Columbamine chloride
    1 Publications Verification

    Columbamin chloride; Dehydroisocorypalmine chloride

    		 Cytochrome P450 Apoptosis Parasite Infection Neurological Disease Inflammation/Immunology Cancer
    Columbamine (Columbamin; Dehydroisocorypalmine) chloride is an organic heterotetracyclic alkaloid extracted from plants. Columbamine chloride is a metabolite of Berberine (HY-N0716). Columbamine chloride inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 30.6 µM). Columbamine chloride induces apoptosis in cancer cells. Columbamine chloride can be used for antioxidant, anti-inflammatory, antitumor, antifungal, antiparasite, hepatoprotective, neuroprotective, hypolipidemic and hypoglycemic study .
    Columbamine chloride
  • HY-134090
    9-Methylstreptimidone

    Antibiotic TS 885; NSC 248958

    		 Bacterial VSV Infection
    9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs=4-20 μg/mL) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all). 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.
    9-Methylstreptimidone
  • HY-113219R
    Hydroxyphenyllactic acid (Standard)

    		Reference Standards Endogenous Metabolite Fungal Infection
    Hydroxyphenyllactic acid (Standard) is the analytical standard of Hydroxyphenyllactic acid. This product is intended for research and analytical applications. Hydroxyphenyllactic acid is an antifungal metabolite.
    Hydroxyphenyllactic acid (Standard)
  • HY-129315
    Deacylketoconazole

    N-Deacetylketoconazole; R-39519

    		 Bacterial Fungal Infection
    Deacylketoconazole (N-Deacetylketoconazole; R-39519) is an orally active metabolite of Ketoconazole (HY-B0105). Deacylketoconazole exhibits antifungal and antibacterial activity. Deacylketoconazole is cytotoxic in rats hepatocyte .
    Deacylketoconazole
  • HY-125706
    1233B

    		Fungal Infection
    1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94 .
    1233B
  • HY-100711A
    Prodigiosin hydrochloride
    3 Publications Verification

    Prodigiosine hydrochloride

    		 Bacterial Apoptosis Fungal Wnt Parasite Infection Inflammation/Immunology Cancer
    Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
    Prodigiosin hydrochloride
  • HY-W010435R
    Sulcatone (Standard)

    6-Methyl-5-hepten-2-one (Standard)

    		 Reference Standards Endogenous Metabolite Fungal Parasite Adenosine Receptor Cytochrome P450 Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Sulcatone (Standard) (6-Methyl-5-hepten-2-one (Standard)) is the analytical standard of Sulcatone (HY-W010435). This product is intended for research and analytical applications. Sulcatone (6-Methyl-5-hepten-2-one) is a plant-derived volatile organic compound with activities such as insecticidal, antifungal, and blood pressure-lowering effects. Sulcatone also serves as an insect pheromone and an endogenous metabolite, which can be found in feces. Changes in Sulcatone levels can be used for the auxiliary diagnosis of ulcerative colitis.
    Sulcatone (Standard)
  • HY-124551
    Viridiol

    		Fungal Infection
    Viridiol, a fungal metabolite from Trichodernza viride, shows antifungal activity .
    Viridiol
  • HY-167831
    Vermistatin

    		Fungal Infection
    Vermistatin is a metabolite of the fungal strain Guignardia that has cytotoxic and antifungal activity .
    Vermistatin
  • HY-122785
    Fusapyrone

    		Fungal Infection
    Fusapyrone is a broad-spectrum antifungal metabolite first isolated from Fusarium species. It has been investigated for use in the control of postharvest crop diseases such as inhibiting the growth of ochratoxin-producing strains of Aspergillus section Nigri in wine grapes.
    Fusapyrone
  • HY-172565
    Posaconazole D-glucuronide

    SCH 56592 D-glucuronide

    		 Drug Metabolite UGT Infection
    Posaconazole D-glucuronide (SCH 56592 D-glucuronide) is a glucuronide metabolite of the antifungal agent Posaconazole (HY-17373). Posaconazole D-glucuronide can be formed in human liver microsomes catalyzed by UGT1A4 .
    Posaconazole D-glucuronide
  • HY-121178
    Deoxyviolacein

    		Bacterial Fungal Infection
    Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein (HY-119809) that has anticancer, antibacterial, and antifungal properties. It inhibits proliferation of hepatocellular carcinoma cells when used at concentrations ranging from 0.1 to 1 μM. Deoxyviolacein (125 μg/mL) has antibacterial activity against Gram-positive bacteria, including S. aureus, B. subtilis, and B. megaterium. It also has antifungal activity against R. solani when used at a concentration of 2 mg/ml.
    Deoxyviolacein
  • HY-N16394
    4-Hydroxyscytalone

    		Endogenous Metabolite Cancer
    4-Hydroxyscytalone (Compound 3) is a microbial secondary metabolite. 4-Hydroxyscytalone can be isolated from the oak fungus Diplodia corticola. 4-Hydroxyscytalone has toxicity against Artemia salina with a LC50 of 90.6 μ/mL, but no significant antifungal activity. 4-Hydroxyscytalone can be used for cancer therapy research .
    4-Hydroxyscytalone
  • HY-B0277R
    Vidarabine (Standard)

    Ara-A (Standard); Adenine Arabinoside (Standard); 9-β-D-Arabinofuranosyladenine (Standard)

    		 Reference Standards Apoptosis Fungal Reactive Oxygen Species (ROS) EBV HSV Antibiotic DNA/RNA Synthesis Drug Metabolite Infection
    Vidarabine (Ara-A) (Standard) is the analytical standard of Vidarabine. This product is intended for research and analytical applications. Vidarabine is a nucleoside antibiotic isolated from Streptomyces, and a metabolite of Vidarabine phosphate (HY-B0277A). Vidarabine selectively inhibits viral DNA polymerase and cellular ribonucleotide reductase, thereby blocking viral replication. Vidarabine phosphate also exhibits antifungal activity, induces late-stage cellular apoptosis, and causes cell cycle arrest. Vidarabine phosphate can be used in research related to severe chronic active Epstein-Barr virus (EBV) infection, herpes infection, and candidiasis .
    Vidarabine (Standard)
  • HY-N10215
    Canadensolide

    		Fungal Endogenous Metabolite Infection
    Canadensolide is an antifungal metabolite of Penicillium canadense.
    Canadensolide
  • HY-N10288
    Eucalyptacid A

    		Fungal Endogenous Metabolite Infection
    Eucalyptacid A, an antifungal metabolite, exhibits antifungal activities against Alternaria solani, with MIC values from 6.25 to 50 μM .
    Eucalyptacid A
  • HY-N8499
    Sporothriolide

    		Fungal Infection
    Sporothriolide is a metabolite produced by Nodulisporium sp. A21. Sporothriolide has potently antifungal against R. solani and S. sclerotiorum, with EC50 values of 11.6 μM and 10.7 μM, respectively. Sporothriolide inhibits conidium germination of Magnaporthe oryzae in vitro and in vivo .
    Sporothriolide
  • HY-N16445
    Strevertene A

    (-)-Strevertene A

    		 Endogenous Metabolite Antibiotic Fungal Infection
    Strevertene A ((-)-Strevertene A) (Compound 1), a pentaene macrolide, is a microbial secondary metabolite. Strevertene A is an antibiotic and has a potent antifungal activity. Strevertene A significantly inhibits the mycelial growth of phytopathogenic fungi (such as Alternaria mali, Aspergillus oryzae and Cylindrocarpon destructans) with IC50s of 4-16 μg/mL. Strevertenes A can strongly prevent Fusarium wilt development on tomato plants .
    Strevertene A
  • HY-N13993
    Aranorosinol A

    		Bacterial Fungal Infection
    Aranorosinol A is a secondary metabolite with weak antibacterial and antifungal properties .
    Aranorosinol A
  • HY-N10289
    Cytosporone C

    		Fungal Infection
    Cytosporone C is an antifungal metabolite from the Melia azedarach-Associated Fungus Diaporthe eucalyptorum. Cytosporone C exhibits antifungal activities against Alternaria solani .
    Cytosporone C
  • HY-I0903
    SCH 51048

    		Fungal Others
    SCH 51048 is a compound that can produce active metabolites, and its active metabolites have antifungal activity. Through metabolic studies and activity screening of the compound, metabolites and compounds with better activity were discovered.
    SCH 51048
  • HY-P10916
    Micafungin metabolite M1

    		Drug Metabolite Fungal Infection
    Micafungin metabolite M1 is an active metabolite of Micafungin (HY-17579), which is metabolized by arylsulfatase and exhibits antifungal activity. Micafungin metabolite M1 can be used for research on deep fungal infections caused by Candida and Aspergillus species .
    Micafungin metabolite M1
  • HY-W741557
    Griseofulvic Acid

    (±)-Griseofulvic acid

    		 Fungal Infection
    Griseofulvic acid is a metabolite of the antifungal Griseofulvin (HY-17583). It induces protein aggregation and tubulin polymerization in cell-free assays.
    Griseofulvic Acid
  • HY-W540874
    1-Heptadecene

    		Fungal Bacterial Infection
    1-Heptadecene is a metabolite found in Aporosa cardiosperma. 1-Heptadecene has antifungal and antibacterial activities .
    1-Heptadecene
  • HY-165017
    Etheroleic acid

    		Fungal Infection
    Etheroleic acid has antifungal activity against the powdery mildew B. graminis on the second leaves of barley seedlings. Etheroleic acid is a metabolite of Linolenic acid .
    Etheroleic acid
  • HY-N15097
    Dihydrocompactin

    		HMG-CoA Reductase (HMGCR) Infection Inflammation/Immunology
    Dihydrocompactin, an antifungal metabolite, is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase (HMG-CoA reductase) from Penicillium citrinum .
    Dihydrocompactin
  • HY-118118
    Phlebiakauranol aldehyde

    		Fungal Infection
    Phlebiakauranol aldehyde is an antifungal and cytotoxic metabolite with strong antifungal activity. Phlebiakauranol aldehyde exhibits significant antibacterial and cytotoxic activities against a variety of plant pathogens. The aldehyde group and high number of hydroxyl groups of Phlebiakauranol aldehyde are considered to be the main reasons for its biological activity. The two acetic acid derivatives of Phlebiakauranol aldehyde only exhibit very weak antifungal and antibacterial activities and moderate cytotoxic activity .
    Phlebiakauranol aldehyde
  • HY-N12893
    Sclerodione

    		Fungal Lipase Infection
    Sclerodione is a metabolite that can be produced by the Scleroderris canker fungus, Gremmeniellaabietina. Sclerodione has antifungal activity. Sclerodione is a lipase inhibitor (IC50: 1 μM) .
    Sclerodione
  • HY-12772S3
    Hydroxy Itraconazole-d6

    R-63373-d6

    		 Isotope-Labeled Compounds Fungal Others
    Hydroxy Itraconazole-d6 (R-63373-d6) is deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
    Hydroxy Itraconazole-d6
  • HY-12772A
    rel-Hydroxy Itraconazole

    rel-R-63373

    		 Drug Isomer Infection
    rel-Hydroxy Itraconazole (rel-R-63373) is a relative stereoisomer of Hydroxy Itraconazole. Hydroxy Itraconazole is the major active metabolite of the antifungal compound Itraconazole (HY-17514) .
    rel-Hydroxy Itraconazole
  • HY-N12260
    Benanomicin A

    		HIV Bacterial Infection
    Benanomicin A is a microbial metabolite and can be isolated from Actinomycetes.Benanomicin has antifungal activitya and inhibits HIV-1 viral infection in MT-4 cells .
    Benanomicin A
  • HY-N11528
    Eugenitol

    7-Noreugenitin

    		 Others Infection
    Eugenitol (Compound 3) is an antifungal metabolite isolated and purified from Diaporthe eucalyptorum. Eugenitol has inhibitory effect on four plant pathogenic fungi (Alternaria solani, Botrytis cinerea, Fusarium solani and Gibberella saubinettii) .
    Eugenitol
  • HY-N10292
    Chaetosemin J

    		Fungal Endogenous Metabolite Infection
    Chaetosemin J, an antifungal metabolite, exhibits inhibitory activity against plant pathogenic fungi Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, with MIC values ranging from 12.5-25 μM .
    Chaetosemin J
  • HY-17011
    Croconazole

    		Fungal Metabolic Disease
    Croconazole is an antifungal agent containing imidazole rings. Croconazole has a unique structural feature of aryl vinyl at the imidazole ring N-1. Croconazole can be used for the identification and quantitative study of major metabolites in rat urine and bile .
    Croconazole
  • HY-N6780
    Ophiobolin B

    		Fungal Infection
    Ophiobolin B, a sesterterpene metabolite of Helminthosporium oryzae, inhibits proton extrusion from maize coleoptiles. Ophiobolin B inhibits fusicoccin (FC) promoted proton extrusion, potassium uptake and cell enlargement . The MIC values with the antifungal effect of Ophiobolins B on different zygomycetes is 25–50 μg/mL .
    Ophiobolin B
  • HY-N15653
    Heveadride

    		Endogenous Metabolite Fungal NF-κB Infection Cancer
    Heveadride is a fungal metabolite and an antifungal agent. Heveadride is active against various filamentous fungi and some human pathogenic yeasts. Heaveadride induces down-regulation of TNFα-induced NF-κB activity in human chronic myeloid leukemia cells with an IC50 of 82.7 μM .
    Heveadride
  • HY-121362R
    Evernic Acid (Standard)

    		Reference Standards Bacterial Endogenous Metabolite Inflammation/Immunology Cancer
    Propazine (Standard) is the analytical standard of Propazine. This product is intended for research and analytical applications. Propazine is a triazine herbicide that effectively manages broad-leaved weeds and annual grasses in sweet sorghum cultivation.
    Evernic Acid (Standard)

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