Sporothriolide
Sporothriolide is a metabolite produced by Nodulisporium sp. A21. Sporothriolide has potently antifungal against R. solani and S. sclerotiorum, with EC50 values of 11.6 μM and 10.7 μM, respectively. Sporothriolide inhibits conidium germination of Magnaporthe oryzae in vitro and in vivo.
For research use only. We do not sell to patients.
- CAS No.: 154799-92-5
- Formula: C13H18O4
- Molecular Weight:238.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
7.1 μM
Compound: 1
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 29043802] |
| MCF7 | IC50 |
4 μM
Compound: 1
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 29043802] |
| PC-3 | IC50 |
6.4 μM
Compound: 1
|
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
|
[PMID: 29043802] |
Chemical Information
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CAS No. 154799-92-5
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Molecular Weight 238.28
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Formula C13H18O4
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SMILES
O=C(O[C@]1([H])[C@@]2([H])C(O[C@@H]1CCCCCC)=O)C2=C
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Structure Classification
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Initial Source
Nodulisporium sp. A21
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)