Palmarumycin C12
Palmarumycin C12 is a fungal metabolite that can be isolated from cultures of Sphaeropsidaes sp. F-24'707. Palmarumycin C12 exhibits antifungal activity. Palmarumycin C12 can be used for the research of fungal infections.
For research use only. We do not sell to patients.
- CAS No.: 159933-97-8
- Formula: C20H14O6
- Molecular Weight:350.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
Fungal Metabolite |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
10 μM
Compound: 17
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Cytotoxicity against human A2780 cells by MTT assay
Cytotoxicity against human A2780 cells by MTT assay
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[PMID: 25237727] |
In Vitro
Palmarumycin C12 shows antifungal activity on Ustilago violacea and Eurotium repens[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 159933-97-8
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Molecular Weight 350.32
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Formula C20H14O6
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SMILES
OC1=C2C3(OC4=CC=CC5=C4C(O3)=CC=C5)[C@@]6([H])[C@]([C@@H](C2=C(C=C1)O)O)([H])O6
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Structure Classification
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Initial Source
Berkleasmium sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Bode HB, et al. Biosynthesis of cladospirone bisepoxide, a member of the spirobisnaphthalene family. J Antibiot (Tokyo). 2000;53(2):153-157. [Content Brief]
[2]. Mou Y, et al. Enhancement of Palmarumycin C12 and C13 Production by the Endophytic Fungus Berkleasmium sp. Dzf12 in an Aqueous-Organic Solvent System. Molecules. 2015;20(11):20320-20333. Published 2015 Nov 12. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Palmarumycin C12 Related Classifications
HY-N19885 Related Classifications
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Keywords
- Palmarumycin C12
- 159933-97-8
- Palmarumycin C 12
- Palmarumycin C-12
- Endogenous Metabolite
- Fungal
- cladospirone bisepoxide
- polyketide
- deoxypreussomerin-type spirobisnaphthalene
- Sphaeropsidaes sp. strain F-24'707
- Berkleasmium sp. Dzf12
- Dioscorea zingiberensis
- fungal infections
- antifungal agent
- 13C NMR spectrum
- fungal metabolite
- Inhibitor
- inhibitor
- inhibit