Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
72 Results for "
gelatinase
" in MedChemExpress (MCE) Product Catalog:
Products (72)
72 Results for "gelatinase" in MCE Product Catalog:
29
29 Publications Verification
SB-3CT is a potent and competitive matrix metalloproteinase MMP-2 and MMP-9 inhibitor with Ki values of 13.9 and 600 nM, respectively. SB-3CT has high selectivity for gelatinases. SB-3CT shows blood-brain barrier permeability and has neuroprotective effects and anticancer activity .
9
9 Cited Publications
Cat. No.: HY-P73296
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP2; Matrix Metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa Type IV Collagenase); Prev. CLG4A; Collagenase Type IV-A; Prev. CLG4; Neutrophil gelatinase; TBE-1; 72 KDa gelatinase; MMP-2; gelatinase A; 72 KDa Type IV Collagenase; MMP-II; Matrix Metalloproteinase-2; MONA; Matrix Metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa Type IV Collagenase); Matrix Metallopeptidase 2; Matrix Metalloproteinase-II
Species:
Human
Source:
HEK293
4
4 Cited Publications
Cat. No.: HY-P73807
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MMP9; Matrix Metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa Type IV Collagenase); Prev. CLG4B; Macrophage gelatinase; Matrix Metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa Type IV Collagenase); Type V Collagenase; Matrix Metalloprot
Species:
Mouse
Source:
HEK293
4
4 Cited Publications
Cat. No.: HY-P70658A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LCN2; P25; Lipocalin 2; Migration-Stimulating Factor Inhibitor; NGAL; Lipocalin 2 (Oncogene 24p3); Neutrophil gelatinase-Associated Lipocalin; Siderocalin LCN2; Oncogene 24p3; Lipocalin-2; 24p3; MSFI; 25 KDa Alpha-2-Microglobulin-Related Subunit Of MMP-9; HNL; Siderocalin
Species:
Mouse
Source:
HEK293
3
3 Cited Publications
Cat. No.: HY-P70268
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP2; Matrix Metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa Type IV Collagenase); Prev. CLG4A; Collagenase Type IV-A; Prev. CLG4; Neutrophil gelatinase; TBE-1; 72 KDa gelatinase; MMP-2; gelatinase A; 72 KDa Type IV Collagenase; MMP-II; Matrix Metalloproteinase-2; MONA; Matrix Metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa Type IV Collagenase); Matrix Metallopeptidase 2; Matrix Metalloproteinase-II
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P73300
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MMP9; Matrix Metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa Type IV Collagenase); Prev. CLG4B; Macrophage gelatinase; Matrix Metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa Type IV Collagenase); Type V Collagenase; Matrix Metalloproteinase-9; 92 KDa gelatinase; MMP-9; gelatinase B; GELB; MANDP2; Matrix Metallopeptidase 9; 92 KDa Type IV Collagenase
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P70351A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP9; Matrix Metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa Type IV Collagenase); Prev. CLG4B; Macrophage gelatinase; Matrix Metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa Type IV Collagenase); Type V Collagenase; Matrix Metalloprot
Species:
Mouse
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P73810
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MMP2; Matrix Metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa Type IV Collagenase); Prev. CLG4A; Collagenase Type IV-A; Prev. CLG4; Neutrophil gelatinase; TBE-1; 72 KDa gelatinase; MMP-2; gelatinase A; 72 KDa Type IV Collagenase; MMP-II; Matrix M
Species:
Mouse
Source:
HEK293
2
2
2 Cited Publications
Cat. No.: HY-P72659A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAP; Prolyl Endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibroblast Activation Protein, Alpha; Integral Membrane Serine Protease; Serine Integral Membrane Protease; Post-Proline Cleaving Enzyme; FAPA; Surface-Expressed Protease
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P700573
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MMP2; Matrix Metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa Type IV Collagenase); Prev. CLG4A; Collagenase Type IV-A; Prev. CLG4; Neutrophil gelatinase; TBE-1; 72 KDa gelatinase; MMP-2; gelatinase A; 72 KDa Type IV Collagenase; MMP-II; Matrix M
Species:
Rat
Source:
P. pastoris
1
1 Cited Publications
Cat. No.: HY-P70658
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LCN2; P25; Lipocalin 2; Migration-Stimulating Factor Inhibitor; NGAL; Lipocalin 2 (Oncogene 24p3); Neutrophil gelatinase-Associated Lipocalin; Siderocalin LCN2; Oncogene 24p3; Lipocalin-2; 24p3; MSFI; 25 KDa Alpha-2-Microglobulin-Related Subunit Of MMP-9
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P77934
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: FAP; Prolyl Endopeptidase FAP; Fibroblast Activation Protein Alpha; Dipeptidyl Peptidase FAP; Seprase; FAPalpha; DPPIV; SIMP; 170 KDa Melanoma Membrane-Bound gelatinase; CDNA FLJ60298, Highly Similar To Seprase; Gelatine Degradation Protease FAP; Fibroblast Activation Protein, Alpha; Integral Membrane Serine Protease; Serine Integral Membrane Protease; Post-Proline Cleaving Enzyme; FAPA; Surface-Expressed Protease
Species:
Mouse
Source:
HEK293
Cat. No.: HY-B1451
CAS No.: 89396-94-1
Synonyms: TA-6366
Imidapril hydrochloride (TA-6366) is an orally active dual inhibitor of angiotensin-converting enzyme (ACE) and MMP-9. Imidapril hydrochloride inhibits lipopolysaccharide-induced phosphorylation of c-Jun, MKK4 and JNK in monocytes, and downregulates the production of specific inflammatory factors such as TNF-α and IP-10, thereby exerting anti-inflammatory activity. Imidapril hydrochloride also effectively ameliorates mesangial expansion and reduces urinary albumin excretion by inhibiting angiotensin AngII production, lowering glomerular pressure and oxidative stress, thus delaying disease progression. Imidapril hydrochloride can also directly bind to the active site of MMP-9 to inhibit gelatinase activity, and suppress the enlargement of cerebral aneurysms without altering systemic blood pressure. Imidapril hydrochloride is widely applicable to related studies on autoimmune glomerulonephritis, diabetic nephropathy, cerebral aneurysms and other conditions .
Cat. No.: HY-B1451A
CAS No.: 89371-37-9
Synonyms: TA-6366 free base
Research Areas:
Imidapril (TA-6366 free base) is an orally active dual inhibitor of angiotensin-converting enzyme (ACE) and MMP-9. Imidapril inhibits lipopolysaccharide-induced phosphorylation of c-Jun, MKK4 and JNK in monocytes, and downregulates the production of specific inflammatory factors such as TNF-α and IP-10, thereby exerting anti-inflammatory activity. Imidapril also effectively ameliorates mesangial expansion and reduces urinary albumin excretion by inhibiting angiotensin AngII production, lowering glomerular pressure and oxidative stress, thus delaying disease progression. Imidapril can also directly bind to the active site of MMP-9 to inhibit gelatinase activity, and suppress the enlargement of cerebral aneurysms without altering systemic blood pressure. Imidapril is widely applicable to related studies on autoimmune glomerulonephritis, diabetic nephropathy, cerebral aneurysms and other conditions .
Cat. No.: HY-P2200
CAS No.: 164802-68-0
Synonyms: BMY-29304
Target:
Research Areas:
Cat. No.: HY-P10143
CAS No.: 99828-55-4
Synonyms: Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
Target:
Research Areas:
DP-b99 is a blood-brain barrier-permeable inhibitor of CYP2C9 and MMP-9, with a Ki value of 4.655 μM against CYP2C9. DP-b99 inhibits CYP2C9 via apparent non-competitive inhibition, mainly chelates pathological Zn 2+ in the membrane environment, attenuates the elevation of intracellular Zn 2+ and Ca 2+ levels, delays seizure onset and reduces seizure severity, and also prevents MMP-9-dependent dendritic spine remodeling, β-dystroglycan cleavage and gelatinase activity. DP-b99 can be used in the research of acute ischemic stroke, epileptogenesis and stroke .
ND-322 hydrochloride is a potent and selective water-soluble gelatinase inhibitor. ND-322 hydrochloride reduces melanoma tumor growth and delays metastatic dissemination .
Cat. No.: HY-E70617
Target:
Research Areas:
Neutrophil Gelatinase Associated Lipocalin (NGAL), Human (EC 6.1.1.3) belongs to the lipocalin family and is primarily secreted by activated neutrophils. The connection of Neutrophil Gelatinase Associated Lipocalin (NGAL), Human to MMP-9 increases the activity of MMP-9 and protects against its degradation. Neutrophil Gelatinase Associated Lipocalin (NGAL), Human is known mainly as a biomarker of acute kidney injury and is released after tubular damage and during renal regeneration processes .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
